Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DK182_RS00890 Genome accession   NZ_CP029491
Coordinates   147253..148296 (+) Length   347 a.a.
NCBI ID   WP_275425199.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 142253..153296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS00870 (DK181_00870) - 142255..142617 (-) 363 WP_019777329.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  DK182_RS00875 (DK181_00875) - 142984..145368 (-) 2385 WP_019777328.1 HAD-IC family P-type ATPase -
  DK182_RS00880 (DK181_00880) - 145588..145956 (+) 369 WP_019781971.1 DUF1033 family protein -
  DK182_RS00885 (DK181_00885) comGA/cglA 146382..147329 (+) 948 WP_019777327.1 competence type IV pilus ATPase ComGA Machinery gene
  DK182_RS00890 (DK181_00890) comYB 147253..148296 (+) 1044 WP_275425199.1 competence type IV pilus assembly protein ComGB Machinery gene
  DK182_RS00895 (DK181_00895) comYC 148293..148619 (+) 327 WP_019777325.1 competence type IV pilus major pilin ComGC Machinery gene
  DK182_RS00900 (DK181_00900) comYD 148573..149007 (+) 435 WP_254051091.1 competence type IV pilus minor pilin ComGD Machinery gene
  DK182_RS00905 (DK181_00905) comYE 148979..149272 (+) 294 WP_002959510.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK182_RS00910 (DK181_00910) comYF 149256..149693 (+) 438 WP_002959513.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK182_RS00915 (DK181_00915) comGG 149671..150132 (+) 462 WP_002959515.1 competence type IV pilus minor pilin ComGG -
  DK182_RS00925 (DK181_00925) - 150334..150600 (+) 267 WP_002959516.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DK182_RS00930 (DK181_00930) - 150587..150862 (+) 276 WP_019777324.1 helix-turn-helix transcriptional regulator -
  DK182_RS00935 (DK181_00935) comYH 150961..151914 (+) 954 WP_019773539.1 class I SAM-dependent methyltransferase Machinery gene
  DK182_RS00940 (DK181_00940) - 151977..153173 (+) 1197 WP_109833408.1 acetate kinase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40050.65 Da        Isoelectric Point: 10.1219

>NTDB_id=293198 DK182_RS00890 WP_275425199.1 147253..148296(+) (comYB) [Streptococcus sobrinus strain 10919]
MKKLTNFLQQDISLRKRRPPKKLKTSRQRKVIQLFNNLLESGFTLTEIVDFLDRSSLLAPADTKEMRASLLAGENLAAMM
GKLGFSDDVVTQLSLAELHGNTQGSLLKIEAYLAHLMTVKRKLWEVATYPIILLTFLILIMLGLRNYLLPQLERTNLATR
IINHFPLVFLIGVLVLALVILCLIWLQRRSRKITWYSRLARLPLLGRFVQLYLTAYYAREWGNLIGQGVEMSRIVQLMQE
QRSQLFQEIGREMEAALLAGQEFHHKVLDYPFFLRELSLIIEYGQVKSKLGSELEVYAQEAWEAFFSRVNRATQLIQPLV
FILVALVIVMIYAAMLLPMYHNMEVPL

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=293198 DK182_RS00890 WP_275425199.1 147253..148296(+) (comYB) [Streptococcus sobrinus strain 10919]
ATGAAAAAATTGACCAACTTCTTGCAGCAGGACATCTCACTGAGGAAGAGGCGGCCGCCGAAAAAATTAAAGACTAGCCG
GCAGCGTAAGGTCATCCAACTCTTCAATAATCTTCTGGAGTCGGGCTTTACCCTAACCGAGATTGTGGATTTTCTGGACC
GCAGTAGCCTTCTGGCTCCGGCCGATACCAAGGAGATGCGGGCCTCCCTCTTGGCGGGGGAAAATTTGGCAGCTATGATG
GGCAAGTTAGGCTTTTCCGATGATGTGGTCACTCAGCTTTCTCTGGCAGAACTGCATGGCAATACCCAAGGCAGTCTCCT
GAAAATCGAGGCTTATCTAGCCCACCTCATGACTGTCAAAAGGAAGCTTTGGGAGGTCGCTACCTATCCCATTATTCTTC
TAACCTTTTTGATTCTGATTATGCTGGGCCTGCGAAATTATCTCTTACCCCAGTTGGAAAGGACCAACCTGGCGACCAGG
ATAATCAATCATTTTCCTCTGGTCTTTCTAATTGGAGTACTGGTTTTGGCCTTAGTCATTCTTTGCTTGATCTGGTTACA
AAGACGGTCGCGAAAAATCACCTGGTACAGCCGCCTGGCTAGACTCCCTTTGCTGGGAAGATTTGTCCAACTCTACTTGA
CTGCCTATTATGCTAGGGAGTGGGGCAATTTGATTGGTCAGGGGGTAGAAATGAGCCGGATTGTCCAACTTATGCAAGAG
CAAAGATCCCAACTCTTCCAGGAGATTGGCCGAGAGATGGAGGCGGCTCTTCTAGCTGGTCAAGAATTCCACCACAAGGT
TTTGGACTATCCCTTCTTCCTTCGGGAATTGAGCCTGATTATTGAATATGGTCAGGTCAAATCTAAATTAGGTAGTGAGC
TGGAGGTCTATGCTCAGGAGGCCTGGGAGGCCTTCTTTAGTCGGGTCAATCGAGCTACTCAGTTGATTCAGCCCTTAGTC
TTTATTCTGGTGGCCCTTGTTATCGTCATGATTTACGCAGCCATGTTGCTGCCCATGTATCACAATATGGAGGTACCTTT
ATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(32-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

65.497

98.559

0.646
  comYB Streptococcus mutans UA140

65.205

98.559

0.643
  comYB Streptococcus gordonii str. Challis substr. CH1

61.047

99.135

0.605
  comGB/cglB Streptococcus mitis NCTC 12261

60.299

96.542

0.582
  comGB/cglB Streptococcus mitis SK321

59.403

96.542

0.573
  comGB/cglB Streptococcus pneumoniae Rx1

58.806

96.542

0.568
  comGB/cglB Streptococcus pneumoniae D39

58.806

96.542

0.568
  comGB/cglB Streptococcus pneumoniae R6

58.806

96.542

0.568
  comGB/cglB Streptococcus pneumoniae TIGR4

58.806

96.542

0.568
  comGB Lactococcus lactis subsp. cremoris KW2

51.032

97.695

0.499

Multiple sequence alignment