Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   DK182_RS00895 Genome accession   NZ_CP029491
Coordinates   148293..148619 (+) Length   108 a.a.
NCBI ID   WP_019777325.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 143293..153619
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS00880 (DK181_00880) - 145588..145956 (+) 369 WP_019781971.1 DUF1033 family protein -
  DK182_RS00885 (DK181_00885) comGA/cglA 146382..147329 (+) 948 WP_019777327.1 competence type IV pilus ATPase ComGA Machinery gene
  DK182_RS00890 (DK181_00890) comYB 147253..148296 (+) 1044 WP_275425199.1 competence type IV pilus assembly protein ComGB Machinery gene
  DK182_RS00895 (DK181_00895) comYC 148293..148619 (+) 327 WP_019777325.1 competence type IV pilus major pilin ComGC Machinery gene
  DK182_RS00900 (DK181_00900) comYD 148573..149007 (+) 435 WP_254051091.1 competence type IV pilus minor pilin ComGD Machinery gene
  DK182_RS00905 (DK181_00905) comYE 148979..149272 (+) 294 WP_002959510.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK182_RS00910 (DK181_00910) comYF 149256..149693 (+) 438 WP_002959513.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK182_RS00915 (DK181_00915) comGG 149671..150132 (+) 462 WP_002959515.1 competence type IV pilus minor pilin ComGG -
  DK182_RS00925 (DK181_00925) - 150334..150600 (+) 267 WP_002959516.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DK182_RS00930 (DK181_00930) - 150587..150862 (+) 276 WP_019777324.1 helix-turn-helix transcriptional regulator -
  DK182_RS00935 (DK181_00935) comYH 150961..151914 (+) 954 WP_019773539.1 class I SAM-dependent methyltransferase Machinery gene
  DK182_RS00940 (DK181_00940) - 151977..153173 (+) 1197 WP_109833408.1 acetate kinase -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12182.25 Da        Isoelectric Point: 10.0056

>NTDB_id=293199 DK182_RS00895 WP_019777325.1 148293..148619(+) (comYC) [Streptococcus sobrinus strain 10919]
MMKKFLKRLKGKKVNAFTLIEMLVVLLIISVLLLLFVPNLAKQKDKVKDTGGSAVVKVVESQAELYELNHSDDATVSKLV
SDGDITQKQADSYNDYYKKHKESRNVPN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=293199 DK182_RS00895 WP_019777325.1 148293..148619(+) (comYC) [Streptococcus sobrinus strain 10919]
ATGATGAAAAAATTTCTCAAACGCCTAAAAGGCAAGAAGGTCAATGCCTTCACCCTGATTGAAATGCTGGTCGTGCTACT
GATTATCAGCGTTTTGCTCCTGCTCTTTGTCCCCAATTTGGCCAAGCAAAAGGATAAGGTCAAGGATACTGGCGGTTCAG
CCGTTGTCAAGGTGGTGGAAAGTCAGGCGGAACTCTATGAACTCAATCATAGCGATGATGCCACGGTATCAAAACTAGTT
TCTGATGGTGACATCACCCAAAAACAGGCGGATTCTTACAATGATTATTACAAGAAACATAAGGAAAGTCGCAACGTTCC
GAACTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus mutans UA140

75.962

96.296

0.731

  comYC Streptococcus mutans UA159

75.962

96.296

0.731

  comYC Streptococcus gordonii str. Challis substr. CH1

67.619

97.222

0.657

  comGC/cglC Streptococcus mitis SK321

67.677

91.667

0.62

  comGC/cglC Streptococcus mitis NCTC 12261

62.617

99.074

0.62

  comGC/cglC Streptococcus pneumoniae TIGR4

63.636

91.667

0.583

  comGC/cglC Streptococcus pneumoniae Rx1

63.636

91.667

0.583

  comGC/cglC Streptococcus pneumoniae D39

63.636

91.667

0.583

  comGC/cglC Streptococcus pneumoniae R6

63.636

91.667

0.583

  comGC Lactococcus lactis subsp. cremoris KW2

61.386

93.519

0.574

  comYC Streptococcus suis isolate S10

62.5

81.481

0.509

  comGC Staphylococcus aureus MW2

50.562

82.407

0.417

  comGC Staphylococcus aureus N315

50.562

82.407

0.417


Multiple sequence alignment