Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   DK182_RS00905 Genome accession   NZ_CP029491
Coordinates   148979..149272 (+) Length   97 a.a.
NCBI ID   WP_002959510.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 143979..154272
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS00880 (DK181_00880) - 145588..145956 (+) 369 WP_019781971.1 DUF1033 family protein -
  DK182_RS00885 (DK181_00885) comGA/cglA 146382..147329 (+) 948 WP_019777327.1 competence type IV pilus ATPase ComGA Machinery gene
  DK182_RS00890 (DK181_00890) comYB 147253..148296 (+) 1044 WP_275425199.1 competence type IV pilus assembly protein ComGB Machinery gene
  DK182_RS00895 (DK181_00895) comYC 148293..148619 (+) 327 WP_019777325.1 competence type IV pilus major pilin ComGC Machinery gene
  DK182_RS00900 (DK181_00900) comYD 148573..149007 (+) 435 WP_254051091.1 competence type IV pilus minor pilin ComGD Machinery gene
  DK182_RS00905 (DK181_00905) comYE 148979..149272 (+) 294 WP_002959510.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK182_RS00910 (DK181_00910) comYF 149256..149693 (+) 438 WP_002959513.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK182_RS00915 (DK181_00915) comGG 149671..150132 (+) 462 WP_002959515.1 competence type IV pilus minor pilin ComGG -
  DK182_RS00925 (DK181_00925) - 150334..150600 (+) 267 WP_002959516.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DK182_RS00930 (DK181_00930) - 150587..150862 (+) 276 WP_019777324.1 helix-turn-helix transcriptional regulator -
  DK182_RS00935 (DK181_00935) comYH 150961..151914 (+) 954 WP_019773539.1 class I SAM-dependent methyltransferase Machinery gene
  DK182_RS00940 (DK181_00940) - 151977..153173 (+) 1197 WP_109833408.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10906.87 Da        Isoelectric Point: 10.6169

>NTDB_id=293201 DK182_RS00905 WP_002959510.1 148979..149272(+) (comYE) [Streptococcus sobrinus strain 10919]
MVAIKKRKIKAYILLESLIALAVLVTIVTLILTEINRDRQELVASLHRQEVLNLAQMAVQTKQDSLSLNGVTVQVQRTST
SIRVYENGREVLHVAKN

Nucleotide


Download         Length: 294 bp        

>NTDB_id=293201 DK182_RS00905 WP_002959510.1 148979..149272(+) (comYE) [Streptococcus sobrinus strain 10919]
GTGGTCGCTATAAAAAAACGGAAAATTAAAGCCTATATTCTCTTAGAAAGCCTGATAGCTCTAGCAGTCTTGGTCACCAT
TGTCACCTTAATCTTGACGGAAATCAACCGAGATCGTCAGGAGCTGGTGGCTAGTCTTCATCGCCAGGAAGTTCTCAACC
TTGCCCAGATGGCAGTTCAGACCAAACAGGACAGTCTCAGTCTGAACGGGGTGACGGTTCAGGTTCAGCGGACTTCGACT
AGTATCAGGGTTTATGAAAATGGCAGGGAGGTTCTCCATGTGGCTAAAAACTAG

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

52.083

98.969

0.515
  comYE Streptococcus mutans UA159

52.083

98.969

0.515
  comGE/cglE Streptococcus pneumoniae D39

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae R6

42.391

94.845

0.402
  comGE/cglE Streptococcus pneumoniae Rx1

42.391

94.845

0.402
  comGE Lactococcus lactis subsp. cremoris KW2

39.362

96.907

0.381
  comGE/cglE Streptococcus mitis NCTC 12261

40.217

94.845

0.381
  comGE/cglE Streptococcus mitis SK321

40.217

94.845

0.381

Multiple sequence alignment