Detailed information NTG0259487

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: CXP32_RS10180
• Genome accession: NZ_CP025256
• Coordinates: 1910022..1911032 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain Xen35
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1905022..1916032

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CXP32_RS10155 (CXP32_10155)	-	1906007..1906301 (-)	295	Protein_1890	hypothetical protein	-
CXP32_RS10160 (CXP32_10160)	-	1906463..1906915 (+)	453	WP_000079148.1	universal stress protein	-
CXP32_RS10165 (CXP32_10165)	-	1906950..1908338 (-)	1389	WP_000453137.1	Cof-type HAD-IIB family hydrolase	-
CXP32_RS10170 (CXP32_10170)	-	1908404..1909366 (+)	963	WP_001124777.1	asparaginase	-
CXP32_RS10175 (CXP32_10175)	-	1909395..1909958 (-)	564	WP_001092024.1	hypothetical protein	-
CXP32_RS10180 (CXP32_10180)	ccpA	1910022..1911032 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
CXP32_RS10185 (CXP32_10185)	-	1911457..1912056 (-)	600	WP_000866703.1	response regulator transcription factor	-
CXP32_RS10190 (CXP32_10190)	-	1912057..1913154 (-)	1098	WP_000893503.1	sensor histidine kinase	-
CXP32_RS10195 (CXP32_10195)	-	1913154..1913891 (-)	738	WP_000832915.1	ABC transporter permease	-
CXP32_RS10200 (CXP32_10200)	-	1913893..1914777 (-)	885	WP_001055978.1	ABC transporter ATP-binding protein	-
CXP32_RS10205 (CXP32_10205)	-	1914764..1914958 (-)	195	WP_000820189.1	hypothetical protein	-
CXP32_RS12465	-	1914955..1915161 (-)	207	Protein_1901	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=259487 CXP32_RS10180 WP_000990607.1 1910022..1911032(-) (ccpA) [Streptococcus pneumoniae strain Xen35]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=259487 CXP32_RS10180 WP_000990607.1 1910022..1911032(-) (ccpA) [Streptococcus pneumoniae strain Xen35]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGGTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568