Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   CO687_RS04155 Genome accession   NZ_CP023511
Coordinates   837176..838114 (+) Length   312 a.a.
NCBI ID   WP_046164736.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_371     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 832176..843114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO687_RS04145 (CO687_04145) rpoC 832806..836453 (+) 3648 WP_048777268.1 DNA-directed RNA polymerase subunit beta' -
  CO687_RS04150 (CO687_04150) - 836704..837063 (+) 360 WP_008810065.1 DUF1033 family protein -
  CO687_RS04155 (CO687_04155) comYA 837176..838114 (+) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  CO687_RS04160 (CO687_04160) comYB 838047..839081 (+) 1035 WP_061582647.1 competence type IV pilus assembly protein ComGB Machinery gene
  CO687_RS04165 (CO687_04165) comYC 839078..839395 (+) 318 WP_045634162.1 competence type IV pilus major pilin ComGC Machinery gene
  CO687_RS04170 (CO687_04170) comYD 839355..839783 (+) 429 WP_096754961.1 competence type IV pilus minor pilin ComGD Machinery gene
  CO687_RS04175 (CO687_04175) comGE/cglE 839755..840048 (+) 294 WP_096754962.1 competence type IV pilus minor pilin ComGE Machinery gene
  CO687_RS04180 (CO687_04180) comGF/cglF 840032..840469 (+) 438 WP_008810059.1 competence type IV pilus minor pilin ComGF Machinery gene
  CO687_RS04185 (CO687_04185) comGG 840450..840881 (+) 432 WP_172858951.1 competence type IV pilus minor pilin ComGG -
  CO687_RS04190 (CO687_04190) comYH 840912..841865 (+) 954 WP_096754963.1 class I SAM-dependent methyltransferase Machinery gene
  CO687_RS04195 (CO687_04195) - 841915..843105 (+) 1191 WP_048777262.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35828.81 Da        Isoelectric Point: 5.4496

>NTDB_id=247955 CO687_RS04155 WP_046164736.1 837176..838114(+) (comYA) [Streptococcus gordonii strain FDAARGOS_371]
MVQKIAQAIVRQAKEECAQDIYFVPKDDCYELYMRIGDERRFIQTYDFDQLAAVISHFKFLAGMNVGEKRRSQLGSCDYR
YDDKETSIRLSTVGDYRGYESLVIRLLHDEETELKFWFTHFPEFREKFKDRGLYLFSGPVGSGKTTLMHQLAQLKFKGQQ
VMSIEDPVEIKQEDMLQLQLNETIGLTYESLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIPGVY
ERLLELGVSEEELKIVLQGICYQRLIGGGGVIDFASNNYQEHEPTVWNQQIDQLLAAGHIHPEQAEAEKIRN

Nucleotide


Download         Length: 939 bp        

>NTDB_id=247955 CO687_RS04155 WP_046164736.1 837176..838114(+) (comYA) [Streptococcus gordonii strain FDAARGOS_371]
ATGGTTCAAAAAATTGCCCAGGCGATTGTCCGGCAGGCTAAGGAAGAGTGTGCTCAGGATATTTATTTTGTACCCAAGGA
TGATTGCTATGAACTTTATATGCGGATTGGTGATGAACGACGCTTCATACAGACTTATGATTTTGACCAATTAGCCGCTG
TGATTAGTCATTTTAAATTTTTAGCTGGGATGAATGTAGGAGAAAAACGTCGCAGTCAGCTGGGATCCTGTGATTATCGT
TATGATGATAAGGAAACATCAATTCGTCTGTCAACTGTAGGTGATTATCGTGGATATGAAAGTTTGGTTATTCGACTTTT
GCACGATGAAGAGACAGAATTGAAGTTTTGGTTTACTCATTTTCCTGAGTTTAGAGAGAAGTTTAAGGATCGAGGACTGT
ATCTTTTTTCGGGACCAGTAGGGAGTGGCAAGACCACTCTCATGCATCAATTAGCTCAGCTAAAATTTAAGGGTCAGCAG
GTTATGTCCATTGAGGATCCTGTTGAAATCAAGCAAGAGGATATGCTTCAGCTACAGCTGAATGAAACGATTGGTCTGAC
CTATGAAAGTCTAATTAAGCTTTCCCTGCGTCACCGTCCGGACTTGCTGATTATTGGAGAAATTCGAGATAGTGAAACTG
CTAGAGCTGTGGTTCGAGCTAGCTTGACGGGAGCTACAGTTTTTTCAACGATTCATGCTAAAAGCATTCCTGGTGTTTAC
GAACGCTTATTGGAATTAGGTGTTAGCGAGGAGGAGTTGAAAATTGTTTTACAGGGTATTTGCTATCAACGCTTGATTGG
GGGAGGAGGTGTGATAGACTTTGCCAGCAACAACTACCAAGAACACGAGCCGACCGTCTGGAATCAGCAGATTGATCAGC
TTCTTGCAGCAGGACATATCCATCCTGAGCAAGCAGAAGCAGAAAAAATTAGGAACTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

99.359

100

0.994
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

78.065

99.359

0.776
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

77.742

99.359

0.772
  comGA/cglA/cilD Streptococcus pneumoniae D39

77.742

99.359

0.772
  comGA/cglA/cilD Streptococcus pneumoniae R6

77.742

99.359

0.772
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

77.742

99.359

0.772
  comYA Streptococcus mutans UA159

67.093

100

0.673
  comYA Streptococcus mutans UA140

67.093

100

0.673
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.064

100

0.651
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

100

0.548

Multiple sequence alignment