Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   CO687_RS04160 Genome accession   NZ_CP023511
Coordinates   838047..839081 (+) Length   344 a.a.
NCBI ID   WP_061582647.1    Uniprot ID   A0AB35FVA3
Organism   Streptococcus gordonii strain FDAARGOS_371     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 833047..844081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CO687_RS04150 (CO687_04150) - 836704..837063 (+) 360 WP_008810065.1 DUF1033 family protein -
  CO687_RS04155 (CO687_04155) comYA 837176..838114 (+) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  CO687_RS04160 (CO687_04160) comYB 838047..839081 (+) 1035 WP_061582647.1 competence type IV pilus assembly protein ComGB Machinery gene
  CO687_RS04165 (CO687_04165) comYC 839078..839395 (+) 318 WP_045634162.1 competence type IV pilus major pilin ComGC Machinery gene
  CO687_RS04170 (CO687_04170) comYD 839355..839783 (+) 429 WP_096754961.1 competence type IV pilus minor pilin ComGD Machinery gene
  CO687_RS04175 (CO687_04175) comGE/cglE 839755..840048 (+) 294 WP_096754962.1 competence type IV pilus minor pilin ComGE Machinery gene
  CO687_RS04180 (CO687_04180) comGF/cglF 840032..840469 (+) 438 WP_008810059.1 competence type IV pilus minor pilin ComGF Machinery gene
  CO687_RS04185 (CO687_04185) comGG 840450..840881 (+) 432 WP_172858951.1 competence type IV pilus minor pilin ComGG -
  CO687_RS04190 (CO687_04190) comYH 840912..841865 (+) 954 WP_096754963.1 class I SAM-dependent methyltransferase Machinery gene
  CO687_RS04195 (CO687_04195) - 841915..843105 (+) 1191 WP_048777262.1 acetate kinase -
  CO687_RS04200 (CO687_04200) - 843153..843818 (+) 666 WP_048777261.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39067.17 Da        Isoelectric Point: 9.1875

>NTDB_id=247956 CO687_RS04160 WP_061582647.1 838047..839081(+) (comYB) [Streptococcus gordonii strain FDAARGOS_371]
MISFLQQDISILSKQKQKKLGTSKQKQVIELFNNLFSSGFHLAETVDFLGRSALLEKNYVQQMRHGLANGQAFSEIMASL
GFSDAVVTQLSLAELHGNLSLALLKIEEYLDNLAKVKKKLIEVATYPMMLLGFLVLIMMGLRNYLLPQLSSQNFATQLIG
HLPTIFLLSVLMLLGLTGAIYLIFKGQKRIPVYSFLARLPFVGSFVKIYLTAYYAREWGNMIGQGLELSQIFQIMQEQRS
VLFQEIGQDLGQALQNGQEFSDKIASYPFFKKELSLIIEYGEVKSKLGSELEIYALKTWEEFFGRVNRTMNLIQPLVFVF
VALMIVLLYAAMLLPLYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=247956 CO687_RS04160 WP_061582647.1 838047..839081(+) (comYB) [Streptococcus gordonii strain FDAARGOS_371]
TTGATCAGCTTCTTGCAGCAGGACATATCCATCCTGAGCAAGCAGAAGCAGAAAAAATTAGGAACTAGCAAGCAAAAGCA
GGTCATTGAACTGTTTAATAATTTATTCTCTAGCGGTTTTCACTTGGCTGAGACTGTGGACTTTTTAGGTCGAAGCGCTC
TTTTGGAGAAGAACTATGTTCAGCAAATGCGTCATGGCCTAGCTAATGGGCAAGCATTTTCAGAGATTATGGCTAGTCTA
GGTTTTTCTGATGCGGTAGTAACCCAGCTGTCATTGGCTGAGTTACATGGGAATTTATCGCTTGCCTTGCTAAAAATAGA
GGAATATCTGGATAATCTTGCGAAGGTAAAAAAGAAGTTAATTGAAGTAGCGACCTATCCCATGATGCTTCTCGGCTTTT
TGGTATTGATTATGATGGGCTTGAGAAATTATTTATTACCCCAACTCAGCAGTCAAAATTTTGCAACGCAACTCATTGGT
CATTTGCCGACTATTTTTCTACTATCTGTCTTAATGTTACTTGGATTAACAGGAGCGATTTATCTGATTTTCAAAGGCCA
GAAACGGATCCCTGTATACTCTTTCTTAGCTCGCCTGCCTTTTGTTGGATCCTTTGTAAAGATTTACCTAACCGCCTATT
ATGCGCGTGAATGGGGCAATATGATTGGACAAGGTTTGGAGCTCAGTCAGATTTTTCAGATTATGCAAGAGCAACGCTCG
GTTTTATTTCAGGAAATTGGTCAGGATTTGGGTCAAGCCTTACAAAACGGTCAAGAATTTTCAGATAAAATTGCTTCGTA
TCCTTTTTTCAAAAAAGAATTGTCTCTAATCATCGAATACGGGGAAGTCAAATCTAAGCTGGGAAGCGAACTAGAAATCT
ATGCTCTTAAGACTTGGGAAGAATTTTTTGGTAGGGTCAATCGGACCATGAATCTGATTCAGCCCCTAGTCTTTGTCTTT
GTAGCCTTGATGATTGTCTTATTGTATGCGGCAATGCTATTGCCCCTTTATCAAAATATGGAGGTTCATCTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(30-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

98.547

100

0.985
  comGB/cglB Streptococcus mitis NCTC 12261

72.727

99.128

0.721
  comGB/cglB Streptococcus mitis SK321

72.619

97.674

0.709
  comGB/cglB Streptococcus pneumoniae TIGR4

71.131

97.674

0.695
  comGB/cglB Streptococcus pneumoniae R6

71.131

97.674

0.695
  comGB/cglB Streptococcus pneumoniae Rx1

71.131

97.674

0.695
  comGB/cglB Streptococcus pneumoniae D39

71.131

97.674

0.695
  comYB Streptococcus mutans UA140

60.058

99.709

0.599
  comYB Streptococcus mutans UA159

59.767

99.709

0.596
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

97.965

0.506

Multiple sequence alignment