Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   CHF41_RS02725 Genome accession   NZ_CP022680
Coordinates   537128..537442 (+) Length   104 a.a.
NCBI ID   WP_075105262.1    Uniprot ID   A0A1Q8E642
Organism   Streptococcus respiraculi strain HTS25     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 532128..542442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CHF41_RS02710 - 534766..535119 (+) 354 WP_119875876.1 DUF1033 family protein -
  CHF41_RS02715 comYA 535227..536177 (+) 951 WP_119875877.1 competence type IV pilus ATPase ComGA Machinery gene
  CHF41_RS02720 comYB 536089..537126 (+) 1038 WP_119875878.1 competence type IV pilus assembly protein ComGB Machinery gene
  CHF41_RS02725 comGC/cglC 537128..537442 (+) 315 WP_075105262.1 competence type IV pilus major pilin ComGC Machinery gene
  CHF41_RS02730 comGD 537402..537830 (+) 429 WP_119875879.1 competence type IV pilus minor pilin ComGD -
  CHF41_RS02735 comYE 537802..538095 (+) 294 WP_119875880.1 competence type IV pilus minor pilin ComGE Machinery gene
  CHF41_RS02740 comYF 538082..538516 (+) 435 WP_119875881.1 competence type IV pilus minor pilin ComGF Machinery gene
  CHF41_RS02745 comGG 538524..538922 (+) 399 WP_162911910.1 competence type IV pilus minor pilin ComGG -
  CHF41_RS02750 comYH 538945..539898 (+) 954 WP_119875883.1 class I SAM-dependent methyltransferase Machinery gene
  CHF41_RS02755 - 539948..541138 (+) 1191 WP_119875884.1 acetate kinase -
  CHF41_RS02760 - 541578..542141 (+) 564 WP_119875885.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 104 a.a.        Molecular weight: 11579.59 Da        Isoelectric Point: 9.9218

>NTDB_id=241556 CHF41_RS02725 WP_075105262.1 537128..537442(+) (comGC/cglC) [Streptococcus respiraculi strain HTS25]
MKKLKKIKVKGFTLIEMLVVLLIISILLLLFVPNLSKQKENAKQTGNAVVVKVVEGQAELYELQNEGEASLSRLVETGAI
TEAQAQAYNEYYAKNTNQSRTVKP

Nucleotide


Download         Length: 315 bp        

>NTDB_id=241556 CHF41_RS02725 WP_075105262.1 537128..537442(+) (comGC/cglC) [Streptococcus respiraculi strain HTS25]
ATGAAAAAATTGAAGAAGATAAAAGTAAAAGGTTTTACATTAATAGAAATGCTCGTTGTCCTACTCATCATCAGTATTCT
TTTGCTCTTGTTTGTCCCAAATTTAAGCAAGCAAAAAGAGAATGCTAAGCAGACAGGAAACGCAGTGGTTGTGAAGGTTG
TTGAAGGACAAGCTGAATTATATGAATTACAAAACGAAGGAGAAGCCAGTCTGTCTCGGTTGGTGGAGACGGGAGCAATT
ACGGAAGCGCAGGCGCAAGCCTACAATGAATATTATGCAAAAAACACAAACCAGTCTCGTACAGTCAAGCCTTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(8-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1Q8E642

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

68.687

95.192

0.654
  comGC/cglC Streptococcus mitis NCTC 12261

67.677

95.192

0.644
  comYC Streptococcus gordonii str. Challis substr. CH1

64.078

99.038

0.635
  comYC Streptococcus mutans UA140

63.725

98.077

0.625
  comYC Streptococcus mutans UA159

63.725

98.077

0.625
  comGC/cglC Streptococcus pneumoniae TIGR4

62.745

98.077

0.615
  comGC/cglC Streptococcus pneumoniae D39

62.745

98.077

0.615
  comGC/cglC Streptococcus pneumoniae Rx1

62.745

98.077

0.615
  comGC/cglC Streptococcus pneumoniae R6

62.745

98.077

0.615
  comGC Lactococcus lactis subsp. cremoris KW2

56

96.154

0.538
  comYC Streptococcus suis isolate S10

63.636

84.615

0.538
  comGC Staphylococcus aureus MW2

48.718

75

0.365
  comGC Staphylococcus aureus N315

48.718

75

0.365

Multiple sequence alignment