Detailed information NTG0240576

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: CG712_RS05265
• Genome accession: NZ_CP022547
• Coordinates: 1012792..1013118 (-)
• Length: 108 a.a.
• NCBI ID: WP_002946126.1
• Uniprot ID: A0A0E2Q1B3
• Organism: Streptococcus thermophilus strain B59671
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1007792..1018118

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CG712_RS10305 (CG712_05260)	-	1008059..1008484 (-)	426	WP_096811681.1	CPBP family intramembrane glutamic endopeptidase	-
CG712_RS05230 (CG712_05265)	-	1008727..1008924 (-)	198	WP_002885716.1	helix-turn-helix transcriptional regulator	-
CG712_RS05235 (CG712_05270)	-	1009173..1010366 (-)	1194	WP_096811682.1	acetate kinase	-
CG712_RS05240 (CG712_05275)	comYH	1010422..1011378 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
CG712_RS05245 (CG712_05280)	comGG	1011423..1011740 (-)	318	WP_096811683.1	competence type IV pilus minor pilin ComGG	-
CG712_RS05250 (CG712_05285)	comYF	1011718..1012155 (-)	438	WP_022096897.1	competence type IV pilus minor pilin ComGF	Machinery gene
CG712_RS05255 (CG712_05290)	comGE	1012172..1012432 (-)	261	WP_096811684.1	competence type IV pilus minor pilin ComGE	-
CG712_RS05260 (CG712_05295)	comYD	1012404..1012832 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
CG712_RS05265 (CG712_05300)	comYC	1012792..1013118 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
CG712_RS05270 (CG712_05305)	comYB	1013115..1014215 (-)	1101	WP_157769911.1	competence type IV pilus assembly protein ComGB	Machinery gene
CG712_RS05275 (CG712_05310)	comGA/cglA/cilD	1014097..1015038 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
CG712_RS05280 (CG712_05315)	-	1015119..1015481 (-)	363	WP_014608746.1	DUF1033 family protein	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11914.00 Da
• Isoelectric Point: 9.9219

>NTDB_id=240576 CG712_RS05265 WP_002946126.1 1012792..1013118(-) (comYC) [Streptococcus thermophilus strain B59671]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGGESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=240576 CG712_RS05265 WP_002946126.1 1012792..1013118(-) (comYC) [Streptococcus thermophilus strain B59671]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

3D structure

• AlphaFold DB: A0A0E2Q1B3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	69.231	96.296	0.667
comYC	Streptococcus mutans UA159	69.231	96.296	0.667
comYC	Streptococcus gordonii str. Challis substr. CH1	63.81	97.222	0.62
comGC/cglC	Streptococcus mitis SK321	62.264	98.148	0.611
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae R6	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae Rx1	58.491	98.148	0.574
comGC/cglC	Streptococcus pneumoniae TIGR4	58.491	98.148	0.574
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361