Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   A6J31_RS08685 Genome accession   NZ_CP020431
Coordinates   1687877..1688818 (-) Length   313 a.a.
NCBI ID   WP_080610975.1    Uniprot ID   A0A1V0GFB0
Organism   Streptococcus sp. FDAARGOS_192     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1682877..1693818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS08645 (A6J31_08580) - 1682952..1684145 (-) 1194 WP_002885831.1 acetate kinase -
  A6J31_RS08650 (A6J31_08585) comYH 1684202..1685158 (-) 957 WP_080610972.1 class I SAM-dependent methyltransferase Machinery gene
  A6J31_RS08655 (A6J31_08590) comGG 1685203..1685520 (-) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  A6J31_RS08660 (A6J31_08595) comYF 1685498..1685935 (-) 438 WP_002887014.1 competence type IV pilus minor pilin ComGF Machinery gene
  A6J31_RS08665 (A6J31_08600) comGE 1685922..1686152 (-) 231 WP_002887015.1 competence type IV pilus minor pilin ComGE -
  A6J31_RS08670 (A6J31_08605) comYD 1686184..1686612 (-) 429 WP_263970040.1 competence type IV pilus minor pilin ComGD Machinery gene
  A6J31_RS08675 (A6J31_08610) comYC 1686572..1686886 (-) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  A6J31_RS08680 (A6J31_08615) comYB 1686895..1687995 (-) 1101 WP_142390728.1 competence type IV pilus assembly protein ComGB Machinery gene
  A6J31_RS08685 (A6J31_08620) comYA 1687877..1688818 (-) 942 WP_080610975.1 competence type IV pilus ATPase ComGA Machinery gene
  A6J31_RS08690 (A6J31_08625) - 1688898..1689260 (-) 363 WP_002887019.1 DUF1033 family protein -
  A6J31_RS08695 (A6J31_08630) rpoC 1689423..1693061 (-) 3639 WP_002887020.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35282.37 Da        Isoelectric Point: 5.7041

>NTDB_id=222898 A6J31_RS08685 WP_080610975.1 1687877..1688818(-) (comYA) [Streptococcus sp. FDAARGOS_192]
MVTEFAKEMIKNADSCGAQDIYVIPRQDTYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSISWNQQLEGLVKQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=222898 A6J31_RS08685 WP_080610975.1 1687877..1688818(-) (comYA) [Streptococcus sp. FDAARGOS_192]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATACTTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTGTCTACCGTTGGGGATTATCGTGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTAGTGTACTGGAATCAAGGAATCCAGCCTATTATGGATGCTTTGGATTATCGTGGCT
TATATCTCTTTGCAGGTCCCGTTGGTTCTGGAAAGACTACGCTTATGCATGAGTTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCGATTGAGGACCCTGTGGAAATTAAACAGGATAATGTTTTGCAACTCCAGGTGAATCAAGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCATTACGTCACCGCCCGGATGTTTTGATTATTGGAGAGATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACGGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCCCTTCAAGGGATTGCCTACATGCGTCTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAATCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTAAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V0GFB0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.63

99.361

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.63

99.361

0.642
  comYA Streptococcus gordonii str. Challis substr. CH1

62.62

100

0.626
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361

Multiple sequence alignment