Detailed information NTG0206824

Bioinformatically predicted

Overview

• Name: comX/sigX
• Type: Regulator
• Locus tag: BSR19_RS00910
• Genome accession: NZ_CP018187
• Coordinates: 156442..156939 (+)
• Length: 165 a.a.
• NCBI ID: WP_060973245.1
• Uniprot ID: A0A2W1I7B4
• Organism: Streptococcus salivarius strain ICDC2
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 151442..161939

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR19_RS00910 (BSR19_00910)	comX/sigX	156442..156939 (+)	498	WP_060973245.1	sigma factor	Regulator
BSR19_RS00915 (BSR19_00915)	-	157047..157889 (-)	843	WP_060973244.1	mechanosensitive ion channel family protein	-
BSR19_RS00920 (BSR19_00920)	tig	158032..159315 (+)	1284	WP_002889721.1	trigger factor	-
BSR19_RS00925 (BSR19_00925)	rpoE	159473..160048 (+)	576	WP_002885605.1	DNA-directed RNA polymerase subunit delta	-
BSR19_RS00930 (BSR19_00930)	-	160301..161905 (+)	1605	WP_156246326.1	CTP synthase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 20039.81 Da
• Isoelectric Point: 4.9953

>NTDB_id=206824 BSR19_RS00910 WP_060973245.1 156442..156939(+) (comX/sigX) [Streptococcus salivarius strain ICDC2]
MEQEVFVHAYEVVRPIVLKASRQYFIQLWDQADMEQEAMMTLYQLLEKFPELKSDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYIEISDIAFCLPNKELDAVDRLVYDEQLNAFRNQLSSEDSTKLDRLLAGECFRGRKKMIRELKFWMVDFDP
YNEDD

Nucleotide

• Length: 498 bp

>NTDB_id=206824 BSR19_RS00910 WP_060973245.1 156442..156939(+) (comX/sigX) [Streptococcus salivarius strain ICDC2]
ATGGAACAAGAAGTTTTTGTTCATGCATATGAAGTTGTAAGGCCGATTGTACTTAAGGCTAGTAGACAATATTTCATCCA
ACTTTGGGACCAAGCTGATATGGAGCAAGAAGCTATGATGACGCTTTATCAGCTTTTAGAAAAGTTTCCTGAATTAAAGT
CTGATGATGATAAGTTACGGCGATATTTTAAAACGAAATTTAGAAATAGACTTAATGATGAGGTTAGAAGGCAGGAGTCT
GTAAAACGACAAGCTAATCGACAATGTTATATCGAAATTTCAGATATTGCTTTTTGTCTCCCAAATAAAGAGTTAGATGC
TGTTGATAGGCTTGTTTATGACGAGCAGCTTAATGCTTTCCGTAATCAGTTGTCTTCGGAAGATTCTACTAAGTTAGACC
GTTTGCTAGCTGGGGAGTGTTTTAGAGGTCGAAAAAAGATGATTCGAGAGTTAAAATTTTGGATGGTTGATTTTGATCCT
TACAATGAAGATGATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A2W1I7B4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX	Streptococcus salivarius strain HSISS4	99.394	100	0.994
comX	Streptococcus salivarius SK126	98.788	100	0.988
comX	Streptococcus thermophilus LMD-9	89.697	100	0.897
comX	Streptococcus thermophilus LMG 18311	89.697	100	0.897
comX	Streptococcus sobrinus strain NIDR 6715-7	40.606	100	0.406
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	42.581	93.939	0.4
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	42.581	93.939	0.4
comX/sigX	Streptococcus mutans UA159	41.667	94.545	0.394
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	41.026	94.545	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX	Streptococcus suis D9	39.869	92.727	0.37
comX/sigX	Streptococcus suis isolate S10	39.869	92.727	0.37
comX/sigX	Streptococcus suis P1/7	39.869	92.727	0.37