Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   BFM96_RS04210 Genome accession   NZ_CP016953
Coordinates   873461..873781 (+) Length   106 a.a.
NCBI ID   WP_068994166.1    Uniprot ID   -
Organism   Streptococcus himalayensis strain HTS2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 868461..878781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS04190 - 868547..870916 (-) 2370 WP_083201742.1 bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase -
  BFM96_RS04195 - 871117..871482 (+) 366 WP_068990721.1 DUF1033 family protein -
  BFM96_RS04200 comGA/cglA/cilD 871544..872485 (+) 942 WP_068990723.1 competence type IV pilus ATPase ComGA Machinery gene
  BFM96_RS04205 comYB 872406..873449 (+) 1044 WP_068994164.1 competence type IV pilus assembly protein ComGB Machinery gene
  BFM96_RS04210 comGC/cglC 873461..873781 (+) 321 WP_068994166.1 competence type IV pilus major pilin ComGC Machinery gene
  BFM96_RS04215 comYD 873792..874169 (+) 378 WP_068990726.1 competence type IV pilus minor pilin ComGD Machinery gene
  BFM96_RS04220 comGE/cglE 874141..874431 (+) 291 WP_068990728.1 competence type IV pilus minor pilin ComGE Machinery gene
  BFM96_RS04225 comGF/cglF 874397..874855 (+) 459 WP_145939743.1 competence type IV pilus minor pilin ComGF Machinery gene
  BFM96_RS04230 comGG 874827..875291 (+) 465 WP_068990735.1 competence type IV pilus minor pilin ComGG -
  BFM96_RS04235 comYH 875335..876282 (+) 948 WP_068990737.1 class I SAM-dependent methyltransferase Machinery gene
  BFM96_RS04240 - 876341..877531 (+) 1191 WP_068990741.1 acetate kinase -

Sequence

Protein


Download         Length: 106 a.a.        Molecular weight: 11666.74 Da        Isoelectric Point: 9.5174

>NTDB_id=194012 BFM96_RS04210 WP_068994166.1 873461..873781(+) (comGC/cglC) [Streptococcus himalayensis strain HTS2]
MKKMKQAQVKAFTLVEMLVVLLIISVLMLLFVPNLTQQKDLVAEKGNAAVVKVVESQAELYELNHPGETATLGKLKEQGQ
ISDNQVKSYQKVIASGKVEQGRVISD

Nucleotide


Download         Length: 321 bp        

>NTDB_id=194012 BFM96_RS04210 WP_068994166.1 873461..873781(+) (comGC/cglC) [Streptococcus himalayensis strain HTS2]
ATGAAAAAGATGAAACAAGCACAGGTAAAAGCATTTACATTGGTAGAAATGCTCGTGGTTCTTTTGATTATTAGCGTGCT
CATGCTCCTTTTTGTTCCTAATTTAACTCAGCAAAAAGACTTGGTGGCAGAAAAAGGCAATGCAGCAGTCGTTAAGGTGG
TTGAAAGTCAAGCAGAATTGTATGAGTTGAACCATCCAGGAGAAACGGCAACTCTAGGGAAATTAAAGGAACAAGGTCAA
ATATCTGACAATCAAGTCAAATCTTATCAAAAAGTGATTGCTTCCGGAAAAGTTGAACAAGGTCGTGTGATTAGTGATTA
A

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(10-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

62.5

98.113

0.613
  comYC Streptococcus gordonii str. Challis substr. CH1

71.111

84.906

0.604
  comGC/cglC Streptococcus mitis SK321

65.306

92.453

0.604
  comGC/cglC Streptococcus pneumoniae R6

67.021

88.679

0.594
  comGC/cglC Streptococcus pneumoniae D39

67.021

88.679

0.594
  comGC/cglC Streptococcus pneumoniae TIGR4

67.021

88.679

0.594
  comGC/cglC Streptococcus pneumoniae Rx1

67.021

88.679

0.594
  comYC Streptococcus mutans UA140

63.83

88.679

0.566
  comYC Streptococcus mutans UA159

63.83

88.679

0.566
  comYC Streptococcus suis isolate S10

64.045

83.962

0.538
  comGC Lactococcus lactis subsp. cremoris KW2

52.525

93.396

0.491

Multiple sequence alignment