Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGE/cglE   Type   Machinery gene
Locus tag   BFM96_RS04220 Genome accession   NZ_CP016953
Coordinates   874141..874431 (+) Length   96 a.a.
NCBI ID   WP_068990728.1    Uniprot ID   -
Organism   Streptococcus himalayensis strain HTS2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 869141..879431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS04195 - 871117..871482 (+) 366 WP_068990721.1 DUF1033 family protein -
  BFM96_RS04200 comGA/cglA/cilD 871544..872485 (+) 942 WP_068990723.1 competence type IV pilus ATPase ComGA Machinery gene
  BFM96_RS04205 comYB 872406..873449 (+) 1044 WP_068994164.1 competence type IV pilus assembly protein ComGB Machinery gene
  BFM96_RS04210 comGC/cglC 873461..873781 (+) 321 WP_068994166.1 competence type IV pilus major pilin ComGC Machinery gene
  BFM96_RS04215 comYD 873792..874169 (+) 378 WP_068990726.1 competence type IV pilus minor pilin ComGD Machinery gene
  BFM96_RS04220 comGE/cglE 874141..874431 (+) 291 WP_068990728.1 competence type IV pilus minor pilin ComGE Machinery gene
  BFM96_RS04225 comGF/cglF 874397..874855 (+) 459 WP_145939743.1 competence type IV pilus minor pilin ComGF Machinery gene
  BFM96_RS04230 comGG 874827..875291 (+) 465 WP_068990735.1 competence type IV pilus minor pilin ComGG -
  BFM96_RS04235 comYH 875335..876282 (+) 948 WP_068990737.1 class I SAM-dependent methyltransferase Machinery gene
  BFM96_RS04240 - 876341..877531 (+) 1191 WP_068990741.1 acetate kinase -

Sequence


Protein


Download         Length: 96 a.a.        Molecular weight: 10799.53 Da        Isoelectric Point: 6.0821

>NTDB_id=194014 BFM96_RS04220 WP_068990728.1 874141..874431(+) (comGE/cglE) [Streptococcus himalayensis strain HTS2]
MEKLRKQAVEGSILLEALLAFSVFAFIATFLLGHIHDSRKEQAQQLAAEEVLRAAKMALQTDKSDLTVNEVDIHVEKSAQ
LLVVYHGKEEIIRVEK

Nucleotide


Download         Length: 291 bp        

>NTDB_id=194014 BFM96_RS04220 WP_068990728.1 874141..874431(+) (comGE/cglE) [Streptococcus himalayensis strain HTS2]
ATGGAAAAATTAAGAAAACAAGCAGTTGAGGGGAGCATTTTATTGGAGGCTCTCCTTGCCTTTAGTGTCTTTGCGTTTAT
TGCAACATTTTTGCTGGGGCATATCCATGATTCTAGAAAGGAACAAGCCCAGCAATTAGCAGCAGAAGAAGTCCTACGTG
CAGCAAAAATGGCCTTACAGACAGATAAAAGTGATTTGACAGTGAATGAGGTGGATATCCATGTGGAAAAATCAGCCCAG
CTTCTTGTCGTCTATCATGGAAAGGAGGAAATCATCCGTGTGGAAAAATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

50

100

0.51

  comGE/cglE Streptococcus pneumoniae D39

50

100

0.51

  comGE/cglE Streptococcus pneumoniae R6

50

100

0.51

  comGE/cglE Streptococcus pneumoniae TIGR4

50

100

0.51

  comGE/cglE Streptococcus mitis NCTC 12261

48.98

100

0.5

  comGE/cglE Streptococcus mitis SK321

48.98

100

0.5

  comYE Streptococcus mutans UA140

37.5

100

0.375

  comYE Streptococcus mutans UA159

37.5

100

0.375


Multiple sequence alignment