Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   BFM96_RS04205 Genome accession   NZ_CP016953
Coordinates   872406..873449 (+) Length   347 a.a.
NCBI ID   WP_068994164.1    Uniprot ID   A0A917A912
Organism   Streptococcus himalayensis strain HTS2     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 867406..878449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFM96_RS04190 - 868547..870916 (-) 2370 WP_083201742.1 bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase -
  BFM96_RS04195 - 871117..871482 (+) 366 WP_068990721.1 DUF1033 family protein -
  BFM96_RS04200 comGA/cglA/cilD 871544..872485 (+) 942 WP_068990723.1 competence type IV pilus ATPase ComGA Machinery gene
  BFM96_RS04205 comYB 872406..873449 (+) 1044 WP_068994164.1 competence type IV pilus assembly protein ComGB Machinery gene
  BFM96_RS04210 comGC/cglC 873461..873781 (+) 321 WP_068994166.1 competence type IV pilus major pilin ComGC Machinery gene
  BFM96_RS04215 comYD 873792..874169 (+) 378 WP_068990726.1 competence type IV pilus minor pilin ComGD Machinery gene
  BFM96_RS04220 comGE/cglE 874141..874431 (+) 291 WP_068990728.1 competence type IV pilus minor pilin ComGE Machinery gene
  BFM96_RS04225 comGF/cglF 874397..874855 (+) 459 WP_145939743.1 competence type IV pilus minor pilin ComGF Machinery gene
  BFM96_RS04230 comGG 874827..875291 (+) 465 WP_068990735.1 competence type IV pilus minor pilin ComGG -
  BFM96_RS04235 comYH 875335..876282 (+) 948 WP_068990737.1 class I SAM-dependent methyltransferase Machinery gene
  BFM96_RS04240 - 876341..877531 (+) 1191 WP_068990741.1 acetate kinase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39532.82 Da        Isoelectric Point: 9.2167

>NTDB_id=194011 BFM96_RS04205 WP_068994164.1 872406..873449(+) (comYB) [Streptococcus himalayensis strain HTS2]
MRKLISFLQQDISVLNKRKAKKLSINKQKKVIELFNNLFSSGFHLAETVNFLGRSALLESVYVDTMRDGLSTGQPFSKIM
GCLGFSDAIVTQLSLAEFHGNVTLSMVKIEEYLENLSKVRKKLIEVATYPLLLLGFLVLIMLGLRNYLLPQMDSSNLATQ
IISHLPQIFLGIVLFLSLSVLAFLVYVRKTAKLKLFSFLANIPILGPYISIYLTAYYAREWGNMIGQGLELGQIFQMMQE
QPSKLFQEIGGDLELALQNGQGFSQKVQDYPFFKKELGLIIEYGEVKSRLGRELEVYAEKTWEEFFTRVNRAMNLVQPLV
FVFVALMIVMLYAAMLLPIYENMEVQI

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=194011 BFM96_RS04205 WP_068994164.1 872406..873449(+) (comYB) [Streptococcus himalayensis strain HTS2]
ATGCGCAAATTGATCAGCTTTTTGCAGCAGGACATATCAGTTTTGAACAAGCGGAAAGCGAAAAAATTATCCATCAATAA
GCAGAAAAAGGTCATTGAACTGTTTAATAATCTCTTTTCAAGTGGTTTTCATTTGGCAGAGACGGTAAATTTTCTAGGTA
GAAGTGCGTTGTTAGAGTCTGTCTATGTGGATACGATGAGAGATGGCTTATCCACAGGTCAACCTTTTTCAAAAATTATG
GGGTGTTTAGGGTTTTCAGATGCTATTGTGACCCAGCTATCCTTGGCTGAGTTTCATGGAAATGTAACGCTGAGTATGGT
CAAGATTGAAGAGTATCTGGAAAATCTTTCTAAGGTTAGAAAGAAACTGATTGAAGTGGCCACCTATCCTCTTTTGCTTT
TGGGATTTTTAGTCTTGATTATGCTGGGGTTGCGGAATTATCTTTTGCCCCAGATGGACAGTAGTAATCTAGCAACTCAG
ATCATCAGTCATTTGCCCCAGATTTTTCTAGGGATTGTACTGTTCCTATCGCTAAGCGTACTAGCCTTTCTCGTGTATGT
CCGCAAAACAGCTAAACTCAAGCTCTTTTCTTTCCTGGCTAACATTCCCATTTTGGGGCCGTACATTAGCATTTATCTAA
CAGCCTACTACGCTAGAGAATGGGGAAATATGATTGGACAGGGCTTGGAGCTCGGTCAGATTTTCCAGATGATGCAGGAG
CAGCCCTCTAAGCTTTTTCAAGAAATTGGAGGAGATTTGGAATTGGCTCTGCAAAATGGACAGGGATTCTCTCAAAAAGT
GCAGGATTATCCCTTTTTCAAAAAGGAATTAGGCCTTATTATCGAATACGGAGAAGTAAAATCCCGCTTAGGGAGAGAGT
TAGAGGTCTATGCTGAAAAGACGTGGGAGGAATTTTTCACGCGGGTCAATCGAGCGATGAATTTGGTTCAGCCCTTGGTC
TTTGTCTTTGTTGCCCTTATGATTGTTATGCTCTATGCAGCGATGTTATTACCAATTTATGAAAATATGGAGGTTCAAAT
CTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

72.093

99.135

0.715
  comGB/cglB Streptococcus mitis NCTC 12261

70.746

96.542

0.683
  comGB/cglB Streptococcus mitis SK321

69.552

96.542

0.671
  comGB/cglB Streptococcus pneumoniae TIGR4

68.06

96.542

0.657
  comGB/cglB Streptococcus pneumoniae R6

68.06

96.542

0.657
  comGB/cglB Streptococcus pneumoniae Rx1

68.06

96.542

0.657
  comGB/cglB Streptococcus pneumoniae D39

68.06

96.542

0.657
  comYB Streptococcus mutans UA140

59.475

98.847

0.588
  comYB Streptococcus mutans UA159

59.475

98.847

0.588
  comGB Lactococcus lactis subsp. cremoris KW2

50.733

98.271

0.499

Multiple sequence alignment