Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   NX99_RS07580 Genome accession   NZ_CP015282
Coordinates   1656142..1656456 (+) Length   104 a.a.
NCBI ID   WP_037611125.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ATCC 27945     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1651142..1661456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NX99_RS07565 (NX99_07425) - 1653768..1654130 (+) 363 WP_002887019.1 DUF1033 family protein -
  NX99_RS07570 (NX99_07430) comGA/cglA/cilD 1654210..1655151 (+) 942 WP_002887018.1 competence type IV pilus ATPase ComGA Machinery gene
  NX99_RS07575 (NX99_07435) comYB 1655033..1656133 (+) 1101 WP_148263031.1 competence type IV pilus assembly protein ComGB Machinery gene
  NX99_RS07580 (NX99_07440) comYC 1656142..1656456 (+) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  NX99_RS07585 (NX99_07445) comYD 1656416..1656844 (+) 429 WP_253183813.1 competence type IV pilus minor pilin ComGD Machinery gene
  NX99_RS07590 (NX99_07450) comGE 1656876..1657106 (+) 231 WP_021144685.1 competence type IV pilus minor pilin ComGE -
  NX99_RS07595 (NX99_07455) comYF 1657093..1657530 (+) 438 WP_021144684.1 competence type IV pilus minor pilin ComGF Machinery gene
  NX99_RS07600 (NX99_07460) comGG 1657508..1657825 (+) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  NX99_RS07605 (NX99_07465) comYH 1657870..1658826 (+) 957 WP_002885753.1 class I SAM-dependent methyltransferase Machinery gene
  NX99_RS07610 (NX99_07470) - 1658883..1660076 (+) 1194 WP_002885831.1 acetate kinase -
  NX99_RS07615 (NX99_07475) - 1660327..1660524 (+) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  NX99_RS07620 (NX99_07480) - 1660536..1661192 (+) 657 WP_084915247.1 CPBP family intramembrane glutamic endopeptidase -

Sequence


Protein


Download         Length: 104 a.a.        Molecular weight: 11428.31 Da        Isoelectric Point: 9.7150

>NTDB_id=178235 NX99_RS07580 WP_037611125.1 1656142..1656456(+) (comYC) [Streptococcus salivarius strain ATCC 27945]
MKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVSEGQI
TQKQADSYNDYYAKHGGESRSVAN

Nucleotide


Download         Length: 315 bp        

>NTDB_id=178235 NX99_RS07580 WP_037611125.1 1656142..1656456(+) (comYC) [Streptococcus salivarius strain ATCC 27945]
TTGAAAAAATTGAATGCCGTTAAATTACGTGCTTTTACGCTGATTGAAATGCTGGTCGTGCTTCTCATTATCAGTATTCT
CCTTTTGCTCTTTGTACCTAACTTGAGCAAGCAGAAGGATTCTGTTAAAGAGACTGGAAATGCGGCTGTGGTCAAGGTCG
TGGATTCTCAAGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTAGCCGCTCTTGTTTCAGAAGGTCAAATC
ACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTGGCGAAAGCCGCTCAGTGGCCAATTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus mutans UA140

70.192

100

0.702

  comYC Streptococcus mutans UA159

70.192

100

0.702

  comYC Streptococcus gordonii str. Challis substr. CH1

64.762

100

0.654

  comGC/cglC Streptococcus mitis SK321

63.636

95.192

0.606

  comGC/cglC Streptococcus mitis NCTC 12261

59.406

97.115

0.577

  comGC Lactococcus lactis subsp. cremoris KW2

58.416

97.115

0.567

  comGC/cglC Streptococcus pneumoniae R6

59.596

95.192

0.567

  comGC/cglC Streptococcus pneumoniae Rx1

59.596

95.192

0.567

  comGC/cglC Streptococcus pneumoniae TIGR4

59.596

95.192

0.567

  comGC/cglC Streptococcus pneumoniae D39

59.596

95.192

0.567

  comYC Streptococcus suis isolate S10

61.364

84.615

0.519

  comGC Staphylococcus aureus MW2

50

75

0.375

  comGC Staphylococcus aureus N315

50

75

0.375


Multiple sequence alignment