Detailed information NTG0178225

Bioinformatically predicted

Overview

• Name: comX
• Type: Regulator
• Locus tag: NX99_RS06110
• Genome accession: NZ_CP015282
• Coordinates: 1387503..1388000 (-)
• Length: 165 a.a.
• NCBI ID: WP_002885610.1
• Uniprot ID: A0A2I1TJX9
• Organism: Streptococcus salivarius strain ATCC 27945
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1382503..1393000

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NX99_RS06090 (NX99_05985)	-	1382537..1384141 (-)	1605	WP_084915107.1	CTP synthase	-
NX99_RS06095 (NX99_05990)	rpoE	1384394..1384969 (-)	576	WP_002885605.1	DNA-directed RNA polymerase subunit delta	-
NX99_RS06100 (NX99_05995)	tig	1385127..1386410 (-)	1284	WP_002885606.1	trigger factor	-
NX99_RS06105 (NX99_06000)	-	1386553..1387395 (+)	843	WP_041826643.1	mechanosensitive ion channel family protein	-
NX99_RS06110 (NX99_06005)	comX	1387503..1388000 (-)	498	WP_002885610.1	sigma factor	Regulator

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 20008.84 Da
• Isoelectric Point: 4.9953

>NTDB_id=178225 NX99_RS06110 WP_002885610.1 1387503..1388000(-) (comX) [Streptococcus salivarius strain ATCC 27945]
MEQEVFVHAYEVVRPIVLKASRQYFIQLWDLADMEQEAMMTLYQLLEKFPELKSDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYIEISDIAFCLPNKELDAVDRLVYDEQLNAFRNQLSSEDATKLDRLLAGECFRGRKKMIRELKFWMVDFDP
YNEDD

Nucleotide

• Length: 498 bp

>NTDB_id=178225 NX99_RS06110 WP_002885610.1 1387503..1388000(-) (comX) [Streptococcus salivarius strain ATCC 27945]
ATGGAACAAGAAGTTTTTGTTCATGCATATGAAGTTGTAAGGCCGATTGTACTTAAGGCTAGTAGACAATATTTCATCCA
ACTTTGGGACCTTGCTGATATGGAGCAAGAGGCTATGATGACACTTTATCAGCTTTTAGAAAAGTTTCCTGAATTAAAGT
CTGATGATGATAAGTTACGGCGTTATTTTAAAACTAAATTTAGGAATAGACTTAATGACGAGGTTAGAAGGCAGGAGTCT
GTAAAACGTCAAGCTAATCGACAATGTTATATTGAAATTTCAGATATTGCTTTTTGTCTTCCAAATAAAGAGTTAGATGC
TGTTGATAGGCTTGTTTATGATGAGCAGCTTAATGCTTTCCGTAATCAGTTGTCTTCGGAAGATGCTACTAAGTTAGACC
GTTTGCTAGCTGGGGAGTGTTTTAGAGGTCGAAAAAAGATGATTCGAGAGTTAAAATTTTGGATGGTTGATTTTGATCCT
TACAATGAAGATGATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A2I1TJX9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX	Streptococcus salivarius SK126	100	100	1
comX/sigX	Streptococcus salivarius strain HSISS4	99.394	100	0.994
comX	Streptococcus thermophilus LMD-9	88.485	100	0.885
comX	Streptococcus thermophilus LMG 18311	88.485	100	0.885
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comX	Streptococcus sobrinus strain NIDR 6715-7	40.606	100	0.406
comX/sigX	Streptococcus mutans UA159	41.667	94.545	0.394
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	41.026	94.545	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX	Streptococcus suis D9	39.869	92.727	0.37
comX/sigX	Streptococcus suis isolate S10	39.869	92.727	0.37
comX/sigX	Streptococcus suis P1/7	39.869	92.727	0.37