Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   AXE83_RS09335 Genome accession   NZ_CP014264
Coordinates   1996425..1996748 (-) Length   107 a.a.
NCBI ID   WP_060956239.1    Uniprot ID   A0A0X8K020
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1991425..2001748
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS09305 (AXE83_09305) - 1992218..1993924 (-) 1707 WP_060956235.1 ABC transporter ATP-binding protein -
  AXE83_RS09310 (AXE83_09310) - 1994116..1994817 (-) 702 WP_049509191.1 histidine phosphatase family protein -
  AXE83_RS09315 (AXE83_09315) comGG 1994927..1995361 (-) 435 WP_060956236.1 competence type IV pilus minor pilin ComGG -
  AXE83_RS09320 (AXE83_09320) comGF/cglF 1995339..1995800 (-) 462 WP_060956237.1 competence type IV pilus minor pilin ComGF Machinery gene
  AXE83_RS09325 (AXE83_09325) comGE/cglE 1995763..1996065 (-) 303 WP_049509188.1 competence type IV pilus minor pilin ComGE Machinery gene
  AXE83_RS09330 (AXE83_09330) comGD/cglD 1996028..1996462 (-) 435 WP_060956238.1 competence type IV pilus minor pilin ComGD Machinery gene
  AXE83_RS09335 (AXE83_09335) comGC/cglC 1996425..1996748 (-) 324 WP_060956239.1 competence type IV pilus major pilin ComGC Machinery gene
  AXE83_RS09340 (AXE83_09340) comGB/cglB 1996749..1997792 (-) 1044 WP_083501012.1 competence type IV pilus assembly protein ComGB Machinery gene
  AXE83_RS09345 (AXE83_09345) comGA/cglA/cilD 1997713..1998654 (-) 942 WP_060956241.1 competence type IV pilus ATPase ComGA Machinery gene
  AXE83_RS09350 (AXE83_09350) - 1998712..1999089 (-) 378 WP_007555701.1 DUF1033 family protein -
  AXE83_RS09355 (AXE83_09355) - 1999227..2000285 (-) 1059 WP_060956242.1 zinc-dependent alcohol dehydrogenase family protein -
  AXE83_RS09360 (AXE83_09360) nagA 2000425..2001576 (-) 1152 WP_060956243.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 107 a.a.        Molecular weight: 11880.06 Da        Isoelectric Point: 10.0527

>NTDB_id=170029 AXE83_RS09335 WP_060956239.1 1996425..1996748(-) (comGC/cglC) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MEKMLMKLKKAKAKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVNDKGKAAVVKVVESQAELYTLDKNEDASLSKLQA
DGRITAEQAKAYKEYHAKQKTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=170029 AXE83_RS09335 WP_060956239.1 1996425..1996748(-) (comGC/cglC) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGGAAAAAATGTTGATGAAATTAAAGAAAGCCAAGGCAAAAGCTTTTACACTGGTAGAAATGTTGGTGGTGTTGCTCAT
CATTAGTGTTCTACTCTTACTGTTTGTGCCAAACCTAACTAAGCAAAAGGATGCAGTGAATGACAAGGGTAAAGCAGCAG
TCGTCAAGGTGGTAGAAAGCCAAGCTGAACTCTATACTCTAGATAAAAATGAGGATGCTAGTCTAAGTAAACTTCAGGCA
GATGGACGCATCACTGCTGAGCAAGCAAAAGCCTATAAGGAATACCATGCAAAACAAAAGACAAGTCAAACAGTTGCGGA
TTAG

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8K020

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

91.589

100

0.916
  comGC/cglC Streptococcus mitis SK321

88.889

92.523

0.822
  comGC/cglC Streptococcus pneumoniae Rx1

86.869

92.523

0.804
  comGC/cglC Streptococcus pneumoniae D39

86.869

92.523

0.804
  comGC/cglC Streptococcus pneumoniae R6

86.869

92.523

0.804
  comGC/cglC Streptococcus pneumoniae TIGR4

85.859

92.523

0.794
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

96.262

0.654
  comYC Streptococcus mutans UA140

67.01

90.654

0.607
  comYC Streptococcus mutans UA159

67.01

90.654

0.607
  comYC Streptococcus suis isolate S10

67.442

80.374

0.542
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

95.327

0.533
  comGC Latilactobacillus sakei subsp. sakei 23K

42.391

85.981

0.364

Multiple sequence alignment