Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   AXE83_RS09340 Genome accession   NZ_CP014264
Coordinates   1996749..1997792 (-) Length   347 a.a.
NCBI ID   WP_083501012.1    Uniprot ID   -
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1991749..2002792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS09305 (AXE83_09305) - 1992218..1993924 (-) 1707 WP_060956235.1 ABC transporter ATP-binding protein -
  AXE83_RS09310 (AXE83_09310) - 1994116..1994817 (-) 702 WP_049509191.1 histidine phosphatase family protein -
  AXE83_RS09315 (AXE83_09315) comGG 1994927..1995361 (-) 435 WP_060956236.1 competence type IV pilus minor pilin ComGG -
  AXE83_RS09320 (AXE83_09320) comGF/cglF 1995339..1995800 (-) 462 WP_060956237.1 competence type IV pilus minor pilin ComGF Machinery gene
  AXE83_RS09325 (AXE83_09325) comGE/cglE 1995763..1996065 (-) 303 WP_049509188.1 competence type IV pilus minor pilin ComGE Machinery gene
  AXE83_RS09330 (AXE83_09330) comGD/cglD 1996028..1996462 (-) 435 WP_060956238.1 competence type IV pilus minor pilin ComGD Machinery gene
  AXE83_RS09335 (AXE83_09335) comGC/cglC 1996425..1996748 (-) 324 WP_060956239.1 competence type IV pilus major pilin ComGC Machinery gene
  AXE83_RS09340 (AXE83_09340) comGB/cglB 1996749..1997792 (-) 1044 WP_083501012.1 competence type IV pilus assembly protein ComGB Machinery gene
  AXE83_RS09345 (AXE83_09345) comGA/cglA/cilD 1997713..1998654 (-) 942 WP_060956241.1 competence type IV pilus ATPase ComGA Machinery gene
  AXE83_RS09350 (AXE83_09350) - 1998712..1999089 (-) 378 WP_007555701.1 DUF1033 family protein -
  AXE83_RS09355 (AXE83_09355) - 1999227..2000285 (-) 1059 WP_060956242.1 zinc-dependent alcohol dehydrogenase family protein -
  AXE83_RS09360 (AXE83_09360) nagA 2000425..2001576 (-) 1152 WP_060956243.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39751.09 Da        Isoelectric Point: 9.6362

>NTDB_id=170030 AXE83_RS09340 WP_083501012.1 1996749..1997792(-) (comGB/cglB) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MDKLTSFLKKDISLPFKLKRRKLATSKQKKIITLFNNLFSSGFHLVEIISFLDRSLLLEKEYVSQMRLGLSQGKSFSEMM
GTLGFSSSIVTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPIILLAFLLLIMLGLRNYLLPQLDSSNIATL
VISNLPQIFLGLTLALGLVSLTGLIFYRKSRKIEVFSFLARIPFLGVFVQYYLTAYYAREWGNMIGQGLELSQIFQMMQE
QGNPLFKEIGHDLSLSLQNGHEFSMVVQDYPFFRRELGLIIEYGEIKSKLGSELEIYAEKTWESFFTRVNRTMNLVQPLV
FIFVALLIVLLYAAMLLPMYQNMEVNF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=170030 AXE83_RS09340 WP_083501012.1 1996749..1997792(-) (comGB/cglB) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGGACAAATTGACCAGCTTCTTAAAGAAGGACATATCACTGCCTTTCAAGCTGAAACGGAGAAAATTAGCTACCAGTAA
GCAGAAGAAAATCATCACTCTCTTTAACAATTTGTTCTCGAGTGGTTTTCACTTGGTAGAGATCATTTCCTTTCTAGATA
GAAGTCTCTTGTTGGAAAAGGAATATGTATCGCAGATGCGTCTAGGACTCTCGCAGGGAAAATCCTTTTCGGAAATGATG
GGGACTTTAGGTTTTTCAAGTTCAATTGTCACGCAACTTTCCTTGGCTGAAGTTCATGGGAACCTTCATTTGAGTTTAGG
GAAAATTGAAGAGTATTTAGATAATCTTGCTAAGGTCAAGAAGAAGTTAATTGAAGTTGCGACCTATCCAATCATATTGT
TAGCTTTCTTACTGCTCATTATGTTGGGGTTGCGAAATTATCTCTTGCCCCAACTGGATAGTAGTAACATAGCTACCTTA
GTGATTAGTAACCTACCACAGATTTTTCTTGGACTTACTCTGGCGCTAGGTCTCGTATCTTTAACAGGACTGATATTCTA
CAGAAAATCTAGGAAGATAGAAGTCTTTTCTTTTCTAGCTAGAATTCCCTTTCTAGGTGTATTTGTTCAGTATTATCTGA
CGGCCTATTATGCTCGAGAATGGGGAAATATGATTGGACAAGGTTTAGAGTTGTCACAGATTTTCCAGATGATGCAGGAG
CAAGGCAATCCTCTTTTTAAGGAAATCGGACATGATTTATCCCTGTCCTTGCAAAATGGGCATGAATTTTCTATGGTTGT
GCAGGATTATCCTTTTTTTAGAAGAGAGTTGGGATTAATCATTGAATATGGAGAGATCAAATCCAAGTTGGGAAGCGAAT
TGGAAATCTATGCAGAAAAAACGTGGGAATCCTTCTTTACCCGAGTTAATCGTACGATGAACTTAGTTCAACCACTGGTC
TTTATTTTTGTAGCTCTGCTAATCGTTTTATTGTACGCAGCTATGTTGCTGCCTATGTATCAAAATATGGAGGTAAATTT
TTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

81.009

97.118

0.787
  comGB/cglB Streptococcus mitis NCTC 12261

80.415

97.118

0.781
  comGB/cglB Streptococcus pneumoniae Rx1

79.822

97.118

0.775
  comGB/cglB Streptococcus pneumoniae D39

79.822

97.118

0.775
  comGB/cglB Streptococcus pneumoniae R6

79.822

97.118

0.775
  comGB/cglB Streptococcus pneumoniae TIGR4

79.822

97.118

0.775
  comYB Streptococcus gordonii str. Challis substr. CH1

70.435

99.424

0.7
  comYB Streptococcus mutans UA140

58.187

98.559

0.573
  comYB Streptococcus mutans UA159

58.187

98.559

0.573
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.118

0.49

Multiple sequence alignment