Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   AXE83_RS09345 Genome accession   NZ_CP014264
Coordinates   1997713..1998654 (-) Length   313 a.a.
NCBI ID   WP_060956241.1    Uniprot ID   A0A0X8JZJ6
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1992713..2003654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS09310 (AXE83_09310) - 1994116..1994817 (-) 702 WP_049509191.1 histidine phosphatase family protein -
  AXE83_RS09315 (AXE83_09315) comGG 1994927..1995361 (-) 435 WP_060956236.1 competence type IV pilus minor pilin ComGG -
  AXE83_RS09320 (AXE83_09320) comGF/cglF 1995339..1995800 (-) 462 WP_060956237.1 competence type IV pilus minor pilin ComGF Machinery gene
  AXE83_RS09325 (AXE83_09325) comGE/cglE 1995763..1996065 (-) 303 WP_049509188.1 competence type IV pilus minor pilin ComGE Machinery gene
  AXE83_RS09330 (AXE83_09330) comGD/cglD 1996028..1996462 (-) 435 WP_060956238.1 competence type IV pilus minor pilin ComGD Machinery gene
  AXE83_RS09335 (AXE83_09335) comGC/cglC 1996425..1996748 (-) 324 WP_060956239.1 competence type IV pilus major pilin ComGC Machinery gene
  AXE83_RS09340 (AXE83_09340) comGB/cglB 1996749..1997792 (-) 1044 WP_083501012.1 competence type IV pilus assembly protein ComGB Machinery gene
  AXE83_RS09345 (AXE83_09345) comGA/cglA/cilD 1997713..1998654 (-) 942 WP_060956241.1 competence type IV pilus ATPase ComGA Machinery gene
  AXE83_RS09350 (AXE83_09350) - 1998712..1999089 (-) 378 WP_007555701.1 DUF1033 family protein -
  AXE83_RS09355 (AXE83_09355) - 1999227..2000285 (-) 1059 WP_060956242.1 zinc-dependent alcohol dehydrogenase family protein -
  AXE83_RS09360 (AXE83_09360) nagA 2000425..2001576 (-) 1152 WP_060956243.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35532.63 Da        Isoelectric Point: 6.1330

>NTDB_id=170031 AXE83_RS09345 WP_060956241.1 1997713..1998654(-) (comGA/cglA/cilD) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MVQILAQELITLAKKQGAQDIYFVPKEKIYELHMRVGDERHLINTYDFEKLGAVISHFKFIAGMNVGEKRRSQLGSCDYQ
HGDKVSSLRLSTVGDYRGHESLVIRLLHDQEQELRFWFQDLIELEKGFRQRGLYLFAGPVGSGKTTLMHELAKSLFKGQQ
VMSIEDPVEIKQEAMLQLQLNEAIGLSYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELGVSEDELAVVLQGVCYQRLIAGGGIIDFANEDYQEHQAEKWNGQIDQLLKEGHITAFQAETEKISYQ

Nucleotide


Download         Length: 942 bp        

>NTDB_id=170031 AXE83_RS09345 WP_060956241.1 1997713..1998654(-) (comGA/cglA/cilD) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGGTACAAATACTTGCACAAGAATTGATTACACTGGCCAAAAAACAAGGAGCTCAGGACATCTATTTTGTTCCTAAAGA
AAAGATTTATGAGCTACATATGCGAGTTGGAGATGAGAGACATTTGATTAACACCTATGACTTTGAAAAGTTGGGGGCTG
TCATTAGTCATTTTAAGTTTATTGCGGGGATGAACGTTGGAGAAAAACGCCGTAGTCAGCTTGGTTCCTGTGATTATCAG
CATGGAGATAAGGTTTCTTCATTACGCTTATCGACGGTGGGAGATTATCGTGGTCATGAGAGTCTAGTAATCCGGCTTTT
GCATGATCAAGAACAAGAGTTGCGCTTCTGGTTTCAGGACCTTATAGAACTGGAAAAGGGCTTTAGGCAACGCGGGCTTT
ATCTTTTTGCAGGCCCCGTAGGAAGCGGCAAAACTACTTTGATGCATGAATTAGCCAAGTCATTGTTTAAGGGACAACAG
GTCATGTCCATTGAAGATCCGGTTGAGATTAAGCAAGAAGCAATGCTACAATTACAGCTCAATGAAGCTATCGGACTTAG
CTATGAGAACTTGATCAAACTTTCCCTACGACATCGTCCAGATCTTTTAATCATTGGAGAAATTCGAGATAGCGAAACAG
CCCGTGCCGTTGTACGAGCTAGTCTGACAGGTGCCACGGTATTCTCGACAATCCATGCCAAGAGTGTTCGTGGGGTTTAT
GAGCGCCTTTTAGAACTTGGTGTCAGTGAAGATGAACTGGCAGTAGTTTTACAAGGTGTTTGTTACCAGAGACTAATCGC
AGGAGGAGGAATTATTGATTTTGCAAACGAAGATTACCAAGAACACCAGGCAGAAAAGTGGAATGGACAAATTGACCAGC
TTCTTAAAGAAGGACATATCACTGCCTTTCAAGCTGAAACGGAGAAAATTAGCTACCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(12-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JZJ6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

85.256

99.681

0.85
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

84.936

99.681

0.847
  comGA/cglA/cilD Streptococcus pneumoniae D39

84.936

99.681

0.847
  comGA/cglA/cilD Streptococcus pneumoniae R6

84.936

99.681

0.847
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

84.936

99.681

0.847
  comYA Streptococcus gordonii str. Challis substr. CH1

76.358

100

0.764
  comYA Streptococcus mutans UA159

63.666

99.361

0.633
  comYA Streptococcus mutans UA140

63.666

99.361

0.633
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

57.508

100

0.575
  comGA Latilactobacillus sakei subsp. sakei 23K

43.885

88.818

0.39

Multiple sequence alignment