Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   AXE83_RS09320 Genome accession   NZ_CP014264
Coordinates   1995339..1995800 (-) Length   153 a.a.
NCBI ID   WP_060956237.1    Uniprot ID   A0A0X8JZI8
Organism   Streptococcus sp. oral taxon 431 strain F0610 (5-114)     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1990339..2000800
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AXE83_RS11505 (AXE83_09300) - 1990450..1992216 (-) 1767 WP_060956234.1 ABC transporter ATP-binding protein -
  AXE83_RS09305 (AXE83_09305) - 1992218..1993924 (-) 1707 WP_060956235.1 ABC transporter ATP-binding protein -
  AXE83_RS09310 (AXE83_09310) - 1994116..1994817 (-) 702 WP_049509191.1 histidine phosphatase family protein -
  AXE83_RS09315 (AXE83_09315) comGG 1994927..1995361 (-) 435 WP_060956236.1 competence type IV pilus minor pilin ComGG -
  AXE83_RS09320 (AXE83_09320) comGF/cglF 1995339..1995800 (-) 462 WP_060956237.1 competence type IV pilus minor pilin ComGF Machinery gene
  AXE83_RS09325 (AXE83_09325) comGE/cglE 1995763..1996065 (-) 303 WP_049509188.1 competence type IV pilus minor pilin ComGE Machinery gene
  AXE83_RS09330 (AXE83_09330) comGD/cglD 1996028..1996462 (-) 435 WP_060956238.1 competence type IV pilus minor pilin ComGD Machinery gene
  AXE83_RS09335 (AXE83_09335) comGC/cglC 1996425..1996748 (-) 324 WP_060956239.1 competence type IV pilus major pilin ComGC Machinery gene
  AXE83_RS09340 (AXE83_09340) comGB/cglB 1996749..1997792 (-) 1044 WP_083501012.1 competence type IV pilus assembly protein ComGB Machinery gene
  AXE83_RS09345 (AXE83_09345) comGA/cglA/cilD 1997713..1998654 (-) 942 WP_060956241.1 competence type IV pilus ATPase ComGA Machinery gene
  AXE83_RS09350 (AXE83_09350) - 1998712..1999089 (-) 378 WP_007555701.1 DUF1033 family protein -
  AXE83_RS09355 (AXE83_09355) - 1999227..2000285 (-) 1059 WP_060956242.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 153 a.a.        Molecular weight: 18084.74 Da        Isoelectric Point: 9.8576

>NTDB_id=170026 AXE83_RS09320 WP_060956237.1 1995339..1995800(-) (comGF/cglF) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
MELKNYWRFKISRVRAFTLLESLVALIVISGSLLLFQSMSQLLVSEVRYQQKSEQKEWLLFVDQLEAELNRAQFEKVEND
RLYLKQDGKPISMGKSKSNDFRKTDASGRGYQPMVYGLKSAHIYQNGQNVHFNFQFEKGLEREFIYRVEKEKS

Nucleotide


Download         Length: 462 bp        

>NTDB_id=170026 AXE83_RS09320 WP_060956237.1 1995339..1995800(-) (comGF/cglF) [Streptococcus sp. oral taxon 431 strain F0610 (5-114)]
ATGGAACTGAAAAATTACTGGCGATTCAAGATAAGTAGAGTCAGAGCGTTTACTCTTTTAGAATCCCTGGTTGCTCTTAT
TGTGATTAGTGGGAGTTTGCTTCTTTTTCAATCTATGAGCCAACTCTTGGTTTCAGAAGTTCGCTACCAGCAGAAAAGTG
AGCAAAAAGAATGGCTTTTATTTGTGGATCAGCTGGAAGCAGAGCTGAATCGAGCCCAATTTGAAAAAGTAGAGAATGAT
AGACTTTACCTCAAACAGGATGGGAAACCTATTTCCATGGGAAAATCAAAGTCAAATGATTTTCGAAAAACAGATGCCAG
TGGACGTGGTTACCAGCCGATGGTTTACGGTCTGAAATCAGCTCATATTTACCAAAACGGGCAAAATGTTCATTTTAATT
TTCAGTTTGAAAAGGGACTAGAGAGGGAGTTTATCTATCGTGTGGAAAAAGAAAAAAGTTAG

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(46-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0X8JZI8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus mitis NCTC 12261

78.523

97.386

0.765
  comGF/cglF Streptococcus mitis SK321

77.852

97.386

0.758
  comGF/cglF Streptococcus pneumoniae Rx1

76.51

97.386

0.745
  comGF/cglF Streptococcus pneumoniae D39

76.51

97.386

0.745
  comGF/cglF Streptococcus pneumoniae R6

76.51

97.386

0.745
  comGF/cglF Streptococcus pneumoniae TIGR4

76.51

97.386

0.745

Multiple sequence alignment