Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ATM98_RS07940 Genome accession   NZ_CP013651
Coordinates   1634502..1635443 (+) Length   313 a.a.
NCBI ID   WP_048691344.1    Uniprot ID   -
Organism   Streptococcus sp. A12     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1629502..1640443
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM98_RS07930 (ATM98_07930) rpoC 1630160..1633813 (+) 3654 WP_061564643.1 DNA-directed RNA polymerase subunit beta' -
  ATM98_RS07935 (ATM98_07935) - 1634019..1634396 (+) 378 WP_061564644.1 DUF1033 family protein -
  ATM98_RS07940 (ATM98_07940) comYA 1634502..1635443 (+) 942 WP_048691344.1 competence type IV pilus ATPase ComGA Machinery gene
  ATM98_RS07945 (ATM98_07945) comYB 1635385..1636407 (+) 1023 WP_061564645.1 competence type IV pilus assembly protein ComGB Machinery gene
  ATM98_RS07950 (ATM98_07950) comYC 1636404..1636721 (+) 318 WP_023022076.1 competence type IV pilus major pilin ComGC Machinery gene
  ATM98_RS07955 (ATM98_07955) comGD/cglD 1636690..1637115 (+) 426 WP_061564646.1 competence type IV pilus minor pilin ComGD Machinery gene
  ATM98_RS07960 (ATM98_07960) comGE 1637081..1637374 (+) 294 WP_061564647.1 competence type IV pilus minor pilin ComGE -
  ATM98_RS07965 (ATM98_07965) comGF/cglF 1637358..1637810 (+) 453 WP_061564817.1 competence type IV pilus minor pilin ComGF Machinery gene
  ATM98_RS07970 (ATM98_07970) comGG 1637776..1638222 (+) 447 WP_061564648.1 competence type IV pilus minor pilin ComGG -
  ATM98_RS07975 (ATM98_07975) comYH 1638254..1639207 (+) 954 WP_061564649.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35678.77 Da        Isoelectric Point: 5.4602

>NTDB_id=163422 ATM98_RS07940 WP_048691344.1 1634502..1635443(+) (comYA) [Streptococcus sp. A12]
MVQEIAQSIIRMASNAEAQDIYFVPRSSDYQLFLRVGDERRFIETYSQEQMVAVVSHFKFMAGMNVGERRRSQLGSCDYS
LGDKVLSLRLSTVGDYRGYESLVIRLLHNEDRELRFWFDQLQELEEKVSKRGLYLFAGPVGSGKTTLMHALAKKKFSGQQ
VMSIEDPVEIKQEEMLQLQLNEAIGMTYDSLIKLSLRHRPDLLLIGEIRDTETARAVIRASLTGVTVFSTIHAKSIPGVY
ERLLELGVSEEELRIVLQGICYQRLIKGGGVTDFAIQDYQNHSSQKWNQQMDALYEAGHIELDQAQAEKIIDC

Nucleotide


Download         Length: 942 bp        

>NTDB_id=163422 ATM98_RS07940 WP_048691344.1 1634502..1635443(+) (comYA) [Streptococcus sp. A12]
ATGGTTCAAGAAATTGCACAATCCATAATTCGAATGGCATCGAATGCCGAAGCTCAGGATATTTATTTTGTTCCTCGATC
GTCAGACTATCAGCTCTTTTTAAGGGTTGGGGATGAGCGACGCTTTATCGAGACCTATTCACAAGAACAAATGGTAGCGG
TCGTCAGCCATTTTAAGTTTATGGCAGGGATGAATGTGGGGGAAAGGCGCCGGAGTCAATTGGGCTCCTGTGACTATTCT
CTAGGGGATAAGGTCTTGTCCTTACGTTTGTCTACTGTGGGAGACTATAGGGGATATGAGAGTTTGGTCATTCGCCTGCT
CCACAATGAGGACCGAGAGCTCCGTTTCTGGTTCGACCAACTTCAAGAGCTAGAAGAGAAGGTGAGTAAGCGGGGGCTCT
ACTTATTTGCAGGTCCAGTCGGATCGGGGAAGACGACACTGATGCATGCCCTGGCCAAGAAGAAATTTTCAGGGCAACAA
GTCATGTCAATTGAAGATCCCGTAGAAATTAAGCAGGAAGAGATGCTGCAACTGCAACTCAATGAAGCGATTGGCATGAC
CTATGATAGCTTGATTAAACTGTCTTTGCGTCATCGCCCAGATCTCCTCCTCATCGGAGAAATCCGTGACACGGAGACAG
CTCGCGCAGTTATTCGGGCTAGTCTGACAGGTGTGACAGTCTTTTCCACCATCCATGCCAAGAGCATTCCTGGGGTTTAT
GAACGCCTATTGGAGTTGGGGGTGAGTGAGGAGGAGTTACGGATTGTCCTTCAAGGGATATGTTACCAGCGTTTGATAAA
GGGAGGAGGTGTCACTGACTTTGCCATCCAAGATTACCAAAACCACTCCAGTCAAAAGTGGAACCAGCAAATGGACGCGC
TTTATGAAGCGGGACATATTGAGCTGGATCAGGCGCAAGCCGAAAAAATTATCGATTGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

75.806

99.042

0.751
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

72.903

99.042

0.722
  comGA/cglA/cilD Streptococcus pneumoniae D39

72.258

99.042

0.716
  comGA/cglA/cilD Streptococcus pneumoniae R6

72.258

99.042

0.716
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

72.258

99.042

0.716
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

72.258

99.042

0.716
  comYA Streptococcus mutans UA159

64.856

100

0.649
  comYA Streptococcus mutans UA140

64.856

100

0.649
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.179

99.681

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

55.949

99.361

0.556
  comGA Latilactobacillus sakei subsp. sakei 23K

41.877

88.498

0.371

Multiple sequence alignment