Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGF/cglF   Type   Machinery gene
Locus tag   ATM98_RS07965 Genome accession   NZ_CP013651
Coordinates   1637358..1637810 (+) Length   150 a.a.
NCBI ID   WP_061564817.1    Uniprot ID   -
Organism   Streptococcus sp. A12     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1632358..1642810
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM98_RS07935 (ATM98_07935) - 1634019..1634396 (+) 378 WP_061564644.1 DUF1033 family protein -
  ATM98_RS07940 (ATM98_07940) comYA 1634502..1635443 (+) 942 WP_048691344.1 competence type IV pilus ATPase ComGA Machinery gene
  ATM98_RS07945 (ATM98_07945) comYB 1635385..1636407 (+) 1023 WP_061564645.1 competence type IV pilus assembly protein ComGB Machinery gene
  ATM98_RS07950 (ATM98_07950) comYC 1636404..1636721 (+) 318 WP_023022076.1 competence type IV pilus major pilin ComGC Machinery gene
  ATM98_RS07955 (ATM98_07955) comGD/cglD 1636690..1637115 (+) 426 WP_061564646.1 competence type IV pilus minor pilin ComGD Machinery gene
  ATM98_RS07960 (ATM98_07960) comGE 1637081..1637374 (+) 294 WP_061564647.1 competence type IV pilus minor pilin ComGE -
  ATM98_RS07965 (ATM98_07965) comGF/cglF 1637358..1637810 (+) 453 WP_061564817.1 competence type IV pilus minor pilin ComGF Machinery gene
  ATM98_RS07970 (ATM98_07970) comGG 1637776..1638222 (+) 447 WP_061564648.1 competence type IV pilus minor pilin ComGG -
  ATM98_RS07975 (ATM98_07975) comYH 1638254..1639207 (+) 954 WP_061564649.1 class I SAM-dependent methyltransferase Machinery gene
  ATM98_RS07980 (ATM98_07980) - 1639256..1640452 (+) 1197 WP_048789482.1 acetate kinase -
  ATM98_RS07985 (ATM98_07985) - 1640604..1641278 (+) 675 WP_223363686.1 type II CAAX endopeptidase family protein -
  ATM98_RS07990 (ATM98_07990) folP 1641438..1642394 (+) 957 WP_061564651.1 dihydropteroate synthase -

Sequence

Protein


Download         Length: 150 a.a.        Molecular weight: 17213.84 Da        Isoelectric Point: 4.8970

>NTDB_id=163426 ATM98_RS07965 WP_061564817.1 1637358..1637810(+) (comGF/cglF) [Streptococcus sp. A12]
MLKRTKLPAFTLLEVLVALLVISGGLLVFQGLTSLLRQELQYQSHIKQEEWLLFQDQLDIELSRSQFEEVRDNKLYLVQD
QKPIAIGLAKGGDIRKTDATGRGYQPLIDGVESAWIEKRGDLVSIQLRFEEGLEREVVYRVVEKDKKEAD

Nucleotide


Download         Length: 453 bp        

>NTDB_id=163426 ATM98_RS07965 WP_061564817.1 1637358..1637810(+) (comGF/cglF) [Streptococcus sp. A12]
CTGTTGAAAAGAACTAAACTGCCAGCCTTTACGTTACTGGAGGTCTTGGTTGCCCTGCTCGTCATCAGCGGTGGTTTATT
AGTGTTTCAAGGATTAACAAGCCTTTTGCGTCAAGAACTCCAGTACCAAAGTCACATCAAGCAAGAGGAGTGGCTTCTCT
TTCAGGACCAGCTGGACATTGAATTGTCTCGTAGCCAATTTGAAGAGGTCAGAGACAACAAACTCTATCTTGTTCAGGAT
CAAAAACCCATAGCCATTGGACTGGCTAAGGGGGGAGATATCCGAAAGACAGATGCGACTGGCCGTGGCTATCAACCGTT
GATAGATGGAGTTGAATCCGCCTGGATTGAAAAAAGAGGAGATCTGGTGTCTATTCAACTGCGCTTTGAAGAAGGGTTAG
AAAGGGAGGTGGTCTACCGTGTGGTGGAAAAGGATAAAAAAGAAGCAGATTGA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(38-134)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGF/cglF Streptococcus pneumoniae Rx1

56.25

96

0.54
  comGF/cglF Streptococcus pneumoniae D39

56.25

96

0.54
  comGF/cglF Streptococcus pneumoniae R6

56.25

96

0.54
  comGF/cglF Streptococcus pneumoniae TIGR4

56.25

96

0.54
  comGF/cglF Streptococcus mitis NCTC 12261

54.676

92.667

0.507
  comGF/cglF Streptococcus mitis SK321

54.676

92.667

0.507
  comYF Streptococcus mutans UA159

41.379

96.667

0.4
  comYF Streptococcus mutans UA140

41.379

96.667

0.4

Multiple sequence alignment