Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   HSISS4_RS09075 Genome accession   NZ_CP013216
Coordinates   1964866..1965807 (-) Length   313 a.a.
NCBI ID   WP_002885658.1    Uniprot ID   -
Organism   Streptococcus salivarius strain HSISS4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1959866..1970807
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS09035 (HSISS4_01759) - 1959941..1961134 (-) 1194 WP_002885831.1 acetate kinase -
  HSISS4_RS09040 (HSISS4_01760) comYH 1961191..1962147 (-) 957 WP_002885753.1 class I SAM-dependent methyltransferase Machinery gene
  HSISS4_RS09045 (HSISS4_01761) comGG 1962192..1962509 (-) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  HSISS4_RS09050 (HSISS4_01762) comYF 1962487..1962924 (-) 438 WP_021144684.1 competence type IV pilus minor pilin ComGF Machinery gene
  HSISS4_RS09055 (HSISS4_01763) comGE 1962911..1963141 (-) 231 WP_021144685.1 competence type IV pilus minor pilin ComGE -
  HSISS4_RS09060 (HSISS4_01764) comYD 1963173..1963601 (-) 429 WP_253183813.1 competence type IV pilus minor pilin ComGD Machinery gene
  HSISS4_RS09065 (HSISS4_01765) comYC 1963561..1963887 (-) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  HSISS4_RS09070 (HSISS4_01766) comYB 1963884..1964984 (-) 1101 WP_144429890.1 competence type IV pilus assembly protein ComGB Machinery gene
  HSISS4_RS09075 (HSISS4_01767) comYA 1964866..1965807 (-) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  HSISS4_RS09080 (HSISS4_01768) - 1965889..1966251 (-) 363 WP_021144688.1 DUF1033 family protein -
  HSISS4_RS09085 (HSISS4_01769) rpoC 1966414..1970052 (-) 3639 WP_002887020.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35283.27 Da        Isoelectric Point: 5.4492

>NTDB_id=160729 HSISS4_RS09075 WP_002885658.1 1964866..1965807(-) (comYA) [Streptococcus salivarius strain HSISS4]
MVTEFAKEMIKNADSCGAQDIYVIPRQDNYELYMRVGQERRLIDVYRPDFMASLIGHFKFVAGMMVGEKRRSQLGSCDYD
CGDGQRVSLRLSTVGDYRGLESLVIRVLHSERRELVYWNQGIQPIMDALDYRGLYLFAGPVGSGKTTLMHELVQERFKGQ
QVISIEDPVEIKQDNVLQLQVNQAIDMTYDNLIKLSLRHRPDVLIIGEIRDKETARAVIRASLTGVTVLSTIHAKSVAGV
YERLLDLGVDKSELDNALQGIAYMRLIKGGGVIDFASENFQSHSSTSWNQQLEGLVQQGYLTEGDIQGEKIKD

Nucleotide


Download         Length: 942 bp        

>NTDB_id=160729 HSISS4_RS09075 WP_002885658.1 1964866..1965807(-) (comYA) [Streptococcus salivarius strain HSISS4]
ATGGTAACAGAATTTGCTAAGGAAATGATCAAAAATGCTGATAGTTGTGGGGCTCAAGACATCTATGTCATTCCACGTCA
GGATAATTACGAGCTCTATATGCGAGTTGGCCAGGAGAGGAGATTAATTGATGTATATCGGCCTGATTTCATGGCTAGTC
TTATTGGTCACTTTAAATTTGTGGCGGGAATGATGGTGGGTGAGAAGCGTAGGAGTCAACTAGGTTCCTGTGACTATGAT
TGTGGTGATGGTCAAAGGGTTTCTCTGCGTTTATCAACCGTTGGGGATTATCGCGGCTTAGAAAGTTTAGTTATTCGTGT
TCTACATTCCGAACGTCGAGAATTGGTGTATTGGAATCAAGGAATCCAGCCGATTATGGATGCTTTGGATTATCGTGGCT
TGTATCTCTTTGCAGGTCCCGTAGGTTCTGGAAAGACTACGCTTATGCATGAATTGGTTCAGGAGCGTTTTAAGGGACAG
CAGGTGATTTCGATTGAAGATCCTGTGGAAATTAAACAGGATAATGTCTTGCAACTCCAGGTAAATCAGGCAATTGACAT
GACCTATGATAATTTGATTAAGCTATCACTACGTCACCGCCCGGATGTTTTGATTATTGGAGAAATTCGAGATAAGGAGA
CTGCTCGAGCGGTTATTAGAGCTAGTCTGACAGGAGTGACTGTTCTTTCAACTATTCACGCAAAGAGTGTGGCAGGTGTT
TATGAGCGTCTTCTGGACCTTGGTGTAGATAAGTCTGAGTTGGATAATGCTCTTCAAGGGATTGCCTATATGCGTTTGAT
TAAGGGAGGAGGTGTGATTGATTTTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAG
GCTTGGTTCAACAAGGATATCTCACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

65.176

100

0.652
  comYA Streptococcus mutans UA140

65.176

100

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.309

99.361

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.309

99.361

0.639
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.897

99.681

0.607
  comGA Lactococcus lactis subsp. cremoris KW2

51.447

99.361

0.511
  comGA Latilactobacillus sakei subsp. sakei 23K

41.697

86.581

0.361

Multiple sequence alignment