Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   HSISS4_RS09070 Genome accession   NZ_CP013216
Coordinates   1963884..1964984 (-) Length   366 a.a.
NCBI ID   WP_144429890.1    Uniprot ID   -
Organism   Streptococcus salivarius strain HSISS4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1958884..1969984
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSISS4_RS09030 (HSISS4_01758) - 1959493..1959690 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  HSISS4_RS09035 (HSISS4_01759) - 1959941..1961134 (-) 1194 WP_002885831.1 acetate kinase -
  HSISS4_RS09040 (HSISS4_01760) comYH 1961191..1962147 (-) 957 WP_002885753.1 class I SAM-dependent methyltransferase Machinery gene
  HSISS4_RS09045 (HSISS4_01761) comGG 1962192..1962509 (-) 318 WP_021144683.1 competence type IV pilus minor pilin ComGG -
  HSISS4_RS09050 (HSISS4_01762) comYF 1962487..1962924 (-) 438 WP_021144684.1 competence type IV pilus minor pilin ComGF Machinery gene
  HSISS4_RS09055 (HSISS4_01763) comGE 1962911..1963141 (-) 231 WP_021144685.1 competence type IV pilus minor pilin ComGE -
  HSISS4_RS09060 (HSISS4_01764) comYD 1963173..1963601 (-) 429 WP_253183813.1 competence type IV pilus minor pilin ComGD Machinery gene
  HSISS4_RS09065 (HSISS4_01765) comYC 1963561..1963887 (-) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  HSISS4_RS09070 (HSISS4_01766) comYB 1963884..1964984 (-) 1101 WP_144429890.1 competence type IV pilus assembly protein ComGB Machinery gene
  HSISS4_RS09075 (HSISS4_01767) comYA 1964866..1965807 (-) 942 WP_002885658.1 competence type IV pilus ATPase ComGA Machinery gene
  HSISS4_RS09080 (HSISS4_01768) - 1965889..1966251 (-) 363 WP_021144688.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41648.61 Da        Isoelectric Point: 9.9778

>NTDB_id=160728 HSISS4_RS09070 WP_144429890.1 1963884..1964984(-) (comYB) [Streptococcus salivarius strain HSISS4]
MPVKISKAIRQPAGTNSWKAWFNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKDNWAVQLVQIFPQLFFVSLCGLLVLSLILYLWVKHQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSNLFRELGADLEEALMLGQSFPDRIATHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=160728 HSISS4_RS09070 WP_144429890.1 1963884..1964984(-) (comYB) [Streptococcus salivarius strain HSISS4]
TTGCCAGTGAAAATTTCCAAAGCCATTCGTCAACCAGCTGGAACCAACAGTTGGAAGGCTTGGTTCAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACTTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGCATGACCAAGGTTC
GCAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTCCTGGGTTTCCTGATTCTGATTATGTTAGGACTTAAAAAT
TATCTTTTACCTCAACTGTTAGAGGGTGATGGTAAGGATAATTGGGCTGTACAGTTGGTTCAAATCTTTCCCCAGCTCTT
CTTTGTGAGTTTGTGTGGACTTCTTGTATTAAGCTTAATTCTTTATCTATGGGTCAAACACCAGCCAGCCCTTGTCTTTT
ACCGACGAATGGCAAAAATCCCTTTCATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGACAAGGCATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCTAATCTCTTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTACTCACCCTTTTTTCACTAAGG
AACTATCCTTGATTATTGCTTATGGAGAGGCCAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCTATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

55.102

93.716

0.516
  comYB Streptococcus mutans UA159

55.102

93.716

0.516
  comYB Streptococcus gordonii str. Challis substr. CH1

51.02

93.716

0.478
  comGB/cglB Streptococcus mitis NCTC 12261

50.144

94.809

0.475
  comGB/cglB Streptococcus mitis SK321

49.704

92.35

0.459
  comGB/cglB Streptococcus pneumoniae Rx1

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae D39

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae R6

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae TIGR4

49.408

92.35

0.456
  comGB Lactococcus lactis subsp. cremoris KW2

45.646

90.984

0.415

Multiple sequence alignment