Detailed information NTG0156749

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: SanJ4206_RS01065
• Genome accession: NZ_CP012719
• Coordinates: 210540..210857 (+)
• Length: 105 a.a.
• NCBI ID: WP_003028473.1
• Uniprot ID: A0A0P0N5S2
• Organism: Streptococcus anginosus strain J4206
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 205540..215857

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4206_RS01035 (SanJ4206_0169)	-	205667..206197 (+)	531	WP_003028466.1	FUSC family protein	-
SanJ4206_RS01040 (SanJ4206_0170)	-	206274..206633 (+)	360	WP_003028467.1	MerR family transcriptional regulator	-
SanJ4206_RS01045 (SanJ4206_0171)	glnA	206672..208018 (+)	1347	WP_022525292.1	type I glutamate--ammonia ligase	-
SanJ4206_RS01050 (SanJ4206_0172)	-	208203..208568 (+)	366	WP_022525291.1	DUF1033 family protein	-
SanJ4206_RS01055 (SanJ4206_0173)	comYA	208638..209579 (+)	942	WP_003028470.1	competence type IV pilus ATPase ComGA	Machinery gene
SanJ4206_RS01060 (SanJ4206_0174)	comYB	209521..210543 (+)	1023	WP_003028472.1	competence type IV pilus assembly protein ComGB	Machinery gene
SanJ4206_RS01065 (SanJ4206_0175)	comYC	210540..210857 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
SanJ4206_RS01070 (SanJ4206_0176)	comYD	210817..211245 (+)	429	WP_037582611.1	competence type IV pilus minor pilin ComGD	Machinery gene
SanJ4206_RS01075 (SanJ4206_0177)	comGE/cglE	211217..211510 (+)	294	WP_003028475.1	competence type IV pilus minor pilin ComGE	Machinery gene
SanJ4206_RS01080 (SanJ4206_0178)	comGF/cglF	211494..211931 (+)	438	WP_003028476.1	competence type IV pilus minor pilin ComGF	Machinery gene
SanJ4206_RS01085	comGG	211912..212238 (+)	327	WP_003028477.1	competence type IV pilus minor pilin ComGG	-
SanJ4206_RS01090 (SanJ4206_0180)	comYH	212306..213259 (+)	954	WP_003028478.1	class I SAM-dependent methyltransferase	Machinery gene
SanJ4206_RS01095 (SanJ4206_0181)	-	213306..214505 (+)	1200	WP_003028479.1	acetate kinase	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11622.72 Da
• Isoelectric Point: 10.1006

>NTDB_id=156749 SanJ4206_RS01065 WP_003028473.1 210540..210857(+) (comYC) [Streptococcus anginosus strain J4206]
MKKLKSLKVKGFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVNEGT
ITDKQAASYKAYYAKHTKEARSVAD

Nucleotide

• Length: 318 bp

>NTDB_id=156749 SanJ4206_RS01065 WP_003028473.1 210540..210857(+) (comYC) [Streptococcus anginosus strain J4206]
ATGAAAAAATTAAAAAGTTTGAAGGTTAAAGGTTTTACTTTAGTAGAGATGTTAGTCGTGCTTCTTATCATCAGTGTTTT
GATGCTCTTATTTGTACCGAATTTGACCAAGCAAAAAGAAGCGGTGACGGAAAAAGGAAATGCAGCGGTGGTAAAAGTTG
TGGAAAGCCAAGCGGAGCTGTTTGAGGTCAATCACACTAATGAAAAAGCGACACTCTCAAAATTAGTCAACGAAGGTACG
ATTACAGACAAGCAAGCGGCATCTTATAAGGCTTACTATGCGAAACATACAAAAGAAGCTCGTTCCGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0P0N5S2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	73.333	100	0.733
comYC	Streptococcus mutans UA159	66.667	100	0.667
comYC	Streptococcus mutans UA140	66.667	100	0.667
comGC/cglC	Streptococcus mitis NCTC 12261	68.627	97.143	0.667
comGC/cglC	Streptococcus mitis SK321	68.627	97.143	0.667
comGC/cglC	Streptococcus pneumoniae R6	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae D39	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae Rx1	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	66.667	97.143	0.648
comYC	Streptococcus suis isolate S10	66.292	84.762	0.562
comGC	Lactococcus lactis subsp. cremoris KW2	54.808	99.048	0.543