Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SanJ4206_RS01060 Genome accession   NZ_CP012719
Coordinates   209521..210543 (+) Length   340 a.a.
NCBI ID   WP_003028472.1    Uniprot ID   -
Organism   Streptococcus anginosus strain J4206     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 204521..215543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS01030 (SanJ4206_0168) - 204833..205516 (+) 684 WP_003028465.1 CHAP domain-containing protein -
  SanJ4206_RS01035 (SanJ4206_0169) - 205667..206197 (+) 531 WP_003028466.1 FUSC family protein -
  SanJ4206_RS01040 (SanJ4206_0170) - 206274..206633 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  SanJ4206_RS01045 (SanJ4206_0171) glnA 206672..208018 (+) 1347 WP_022525292.1 type I glutamate--ammonia ligase -
  SanJ4206_RS01050 (SanJ4206_0172) - 208203..208568 (+) 366 WP_022525291.1 DUF1033 family protein -
  SanJ4206_RS01055 (SanJ4206_0173) comYA 208638..209579 (+) 942 WP_003028470.1 competence type IV pilus ATPase ComGA Machinery gene
  SanJ4206_RS01060 (SanJ4206_0174) comYB 209521..210543 (+) 1023 WP_003028472.1 competence type IV pilus assembly protein ComGB Machinery gene
  SanJ4206_RS01065 (SanJ4206_0175) comYC 210540..210857 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  SanJ4206_RS01070 (SanJ4206_0176) comYD 210817..211245 (+) 429 WP_037582611.1 competence type IV pilus minor pilin ComGD Machinery gene
  SanJ4206_RS01075 (SanJ4206_0177) comGE/cglE 211217..211510 (+) 294 WP_003028475.1 competence type IV pilus minor pilin ComGE Machinery gene
  SanJ4206_RS01080 (SanJ4206_0178) comGF/cglF 211494..211931 (+) 438 WP_003028476.1 competence type IV pilus minor pilin ComGF Machinery gene
  SanJ4206_RS01085 comGG 211912..212238 (+) 327 WP_003028477.1 competence type IV pilus minor pilin ComGG -
  SanJ4206_RS01090 (SanJ4206_0180) comYH 212306..213259 (+) 954 WP_003028478.1 class I SAM-dependent methyltransferase Machinery gene
  SanJ4206_RS01095 (SanJ4206_0181) - 213306..214505 (+) 1200 WP_003028479.1 acetate kinase -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 39106.15 Da        Isoelectric Point: 9.8316

>NTDB_id=156748 SanJ4206_RS01060 WP_003028472.1 209521..210543(+) (comYB) [Streptococcus anginosus strain J4206]
MQQDISILNKQKRKKLSTVKQKKVVELLNNLFSSGFHLAEIIDFLKRSALLEEVYVDRMKEGLSTGKSFSDIMASLGFSD
NVVTQLSLAELHGNLSLSLSKIEEYLENVSKIKKKLVEVATYPFILFVFLIFIMLGLRNYLLPQLDRQNVATQIISNLPQ
LFLGSLGVVFVLLAIGFYWFQKNSKITTFGLLARLPFFGAFIQTYLTAYYAREWGNMIGQGLELSQIFQMMQGQRSAMFQ
EIGKDLEVALQNGQEFSKRVKTYPFFKKELGLMIEYGEVKSRLGRELEVYAQKTWETFFKRVHQAMNVIQPLVFVFVALM
IVLLYAAMLLPIYQNMEVQL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=156748 SanJ4206_RS01060 WP_003028472.1 209521..210543(+) (comYB) [Streptococcus anginosus strain J4206]
ATGCAGCAGGACATATCAATCTTGAACAAGCAGAAGCGGAAAAAATTATCCACAGTTAAGCAGAAAAAGGTCGTAGAGTT
ACTGAATAATCTTTTTTCTAGTGGCTTTCATTTGGCAGAAATTATCGACTTTTTGAAGCGAAGTGCCTTGTTAGAAGAAG
TCTATGTGGACAGGATGAAAGAGGGGTTGTCAACAGGAAAGTCTTTTTCGGACATCATGGCAAGCTTAGGTTTTTCAGAT
AATGTAGTAACACAACTTTCGCTGGCAGAATTACACGGAAATCTCTCACTCAGCCTGAGTAAGATTGAGGAATACTTGGA
AAATGTCTCAAAAATTAAGAAAAAGTTGGTTGAAGTGGCGACTTATCCCTTTATTTTGTTTGTCTTTTTGATATTCATTA
TGCTGGGGTTACGTAATTATTTACTCCCGCAACTCGATCGTCAAAATGTAGCAACGCAGATTATCAGTAATTTGCCGCAA
CTTTTTCTGGGTTCATTAGGAGTAGTCTTTGTTTTGTTAGCGATAGGTTTTTATTGGTTCCAAAAAAACTCAAAAATAAC
AACATTTGGCTTGTTAGCTCGCCTTCCCTTTTTTGGCGCTTTTATTCAAACGTATTTGACAGCTTATTATGCGAGAGAAT
GGGGAAATATGATTGGTCAAGGTTTAGAACTTAGTCAGATTTTTCAGATGATGCAAGGACAACGCTCTGCTATGTTTCAA
GAAATTGGGAAAGATTTAGAAGTTGCACTGCAAAATGGTCAGGAATTTTCGAAAAGGGTTAAAACATACCCATTTTTTAA
AAAGGAATTGGGCTTGATGATCGAATACGGCGAAGTGAAGTCTAGATTGGGGCGTGAATTAGAAGTTTATGCTCAAAAAA
CATGGGAGACATTTTTTAAACGTGTTCACCAAGCGATGAATGTCATCCAACCACTAGTGTTTGTCTTTGTGGCTTTAATG
ATTGTATTGTTGTATGCAGCCATGTTGCTGCCAATTTATCAAAATATGGAGGTTCAATTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

70.294

100

0.703
  comGB/cglB Streptococcus mitis NCTC 12261

67.761

98.529

0.668
  comGB/cglB Streptococcus mitis SK321

67.164

98.529

0.662
  comGB/cglB Streptococcus pneumoniae TIGR4

66.866

98.529

0.659
  comGB/cglB Streptococcus pneumoniae R6

66.866

98.529

0.659
  comGB/cglB Streptococcus pneumoniae Rx1

66.866

98.529

0.659
  comGB/cglB Streptococcus pneumoniae D39

66.866

98.529

0.659
  comYB Streptococcus mutans UA159

60.526

100

0.609
  comYB Streptococcus mutans UA140

60.234

100

0.606
  comGB Lactococcus lactis subsp. cremoris KW2

51.335

99.118

0.509

Multiple sequence alignment