Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SanJ4206_RS01075 Genome accession   NZ_CP012719
Coordinates   211217..211510 (+) Length   97 a.a.
NCBI ID   WP_003028475.1    Uniprot ID   -
Organism   Streptococcus anginosus strain J4206     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 206217..216510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS01040 (SanJ4206_0170) - 206274..206633 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  SanJ4206_RS01045 (SanJ4206_0171) glnA 206672..208018 (+) 1347 WP_022525292.1 type I glutamate--ammonia ligase -
  SanJ4206_RS01050 (SanJ4206_0172) - 208203..208568 (+) 366 WP_022525291.1 DUF1033 family protein -
  SanJ4206_RS01055 (SanJ4206_0173) comYA 208638..209579 (+) 942 WP_003028470.1 competence type IV pilus ATPase ComGA Machinery gene
  SanJ4206_RS01060 (SanJ4206_0174) comYB 209521..210543 (+) 1023 WP_003028472.1 competence type IV pilus assembly protein ComGB Machinery gene
  SanJ4206_RS01065 (SanJ4206_0175) comYC 210540..210857 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  SanJ4206_RS01070 (SanJ4206_0176) comYD 210817..211245 (+) 429 WP_037582611.1 competence type IV pilus minor pilin ComGD Machinery gene
  SanJ4206_RS01075 (SanJ4206_0177) comGE/cglE 211217..211510 (+) 294 WP_003028475.1 competence type IV pilus minor pilin ComGE Machinery gene
  SanJ4206_RS01080 (SanJ4206_0178) comGF/cglF 211494..211931 (+) 438 WP_003028476.1 competence type IV pilus minor pilin ComGF Machinery gene
  SanJ4206_RS01085 comGG 211912..212238 (+) 327 WP_003028477.1 competence type IV pilus minor pilin ComGG -
  SanJ4206_RS01090 (SanJ4206_0180) comYH 212306..213259 (+) 954 WP_003028478.1 class I SAM-dependent methyltransferase Machinery gene
  SanJ4206_RS01095 (SanJ4206_0181) - 213306..214505 (+) 1200 WP_003028479.1 acetate kinase -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10875.80 Da        Isoelectric Point: 9.1244

>NTDB_id=156751 SanJ4206_RS01075 WP_003028475.1 211217..211510(+) (comGE/cglE) [Streptococcus anginosus strain J4206]
MENLRKQCVRGTILLEALLALAVFATIVTLLLGQIHQSRKAENDLLREEEVLRVAKMALQTKQSHLTMNGIEVRVETSQQ
GIQIYHGKELILGVQGK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=156751 SanJ4206_RS01075 WP_003028475.1 211217..211510(+) (comGE/cglE) [Streptococcus anginosus strain J4206]
ATGGAAAATTTAAGAAAACAATGCGTTAGAGGAACAATTTTATTAGAGGCGCTGCTGGCTTTGGCTGTTTTTGCGACAAT
TGTGACCCTGTTGTTGGGACAAATTCACCAGTCTCGAAAAGCAGAAAATGACTTGCTTAGAGAAGAAGAAGTTTTAAGGG
TAGCTAAAATGGCTTTGCAGACAAAGCAAAGCCATTTGACAATGAATGGTATTGAAGTGCGTGTTGAAACAAGTCAACAA
GGTATTCAAATTTATCATGGGAAGGAGCTGATTCTCGGTGTTCAAGGCAAATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae D39

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae R6

55.435

94.845

0.526
  comGE/cglE Streptococcus pneumoniae TIGR4

55.435

94.845

0.526
  comGE/cglE Streptococcus mitis NCTC 12261

54.348

94.845

0.515
  comGE/cglE Streptococcus mitis SK321

54.348

94.845

0.515
  comYE Streptococcus mutans UA140

43.434

100

0.443
  comYE Streptococcus mutans UA159

43.434

100

0.443

Multiple sequence alignment