Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   SanJ4206_RS01055 Genome accession   NZ_CP012719
Coordinates   208638..209579 (+) Length   313 a.a.
NCBI ID   WP_003028470.1    Uniprot ID   -
Organism   Streptococcus anginosus strain J4206     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 203638..214579
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS01030 (SanJ4206_0168) - 204833..205516 (+) 684 WP_003028465.1 CHAP domain-containing protein -
  SanJ4206_RS01035 (SanJ4206_0169) - 205667..206197 (+) 531 WP_003028466.1 FUSC family protein -
  SanJ4206_RS01040 (SanJ4206_0170) - 206274..206633 (+) 360 WP_003028467.1 MerR family transcriptional regulator -
  SanJ4206_RS01045 (SanJ4206_0171) glnA 206672..208018 (+) 1347 WP_022525292.1 type I glutamate--ammonia ligase -
  SanJ4206_RS01050 (SanJ4206_0172) - 208203..208568 (+) 366 WP_022525291.1 DUF1033 family protein -
  SanJ4206_RS01055 (SanJ4206_0173) comYA 208638..209579 (+) 942 WP_003028470.1 competence type IV pilus ATPase ComGA Machinery gene
  SanJ4206_RS01060 (SanJ4206_0174) comYB 209521..210543 (+) 1023 WP_003028472.1 competence type IV pilus assembly protein ComGB Machinery gene
  SanJ4206_RS01065 (SanJ4206_0175) comYC 210540..210857 (+) 318 WP_003028473.1 competence type IV pilus major pilin ComGC Machinery gene
  SanJ4206_RS01070 (SanJ4206_0176) comYD 210817..211245 (+) 429 WP_037582611.1 competence type IV pilus minor pilin ComGD Machinery gene
  SanJ4206_RS01075 (SanJ4206_0177) comGE/cglE 211217..211510 (+) 294 WP_003028475.1 competence type IV pilus minor pilin ComGE Machinery gene
  SanJ4206_RS01080 (SanJ4206_0178) comGF/cglF 211494..211931 (+) 438 WP_003028476.1 competence type IV pilus minor pilin ComGF Machinery gene
  SanJ4206_RS01085 comGG 211912..212238 (+) 327 WP_003028477.1 competence type IV pilus minor pilin ComGG -
  SanJ4206_RS01090 (SanJ4206_0180) comYH 212306..213259 (+) 954 WP_003028478.1 class I SAM-dependent methyltransferase Machinery gene
  SanJ4206_RS01095 (SanJ4206_0181) - 213306..214505 (+) 1200 WP_003028479.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35806.02 Da        Isoelectric Point: 6.0555

>NTDB_id=156747 SanJ4206_RS01055 WP_003028470.1 208638..209579(+) (comYA) [Streptococcus anginosus strain J4206]
MVQNIAQAIICQAKEEQAQDIYVVPKENMYELYMRIGDERRFIQQYAFEEMAAVISHFKFTAGMNVGEKRRSQLGSCDYQ
YGDKQTSLRLSTVGDYRGYESLVIRLLHDEEAELKFWFAQIPELKERFKQRGLYLFSGPVGSGKTTLMHQLAQERFAGQQ
IMSIEDPVEIKQPSMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDGETARAVVRASLTGVTVFSTIHAKSVRGVY
ERLLELGVTEAELKIVLQGICYQRLIAKGGIVDFVSEKYQEHEPIDWNRQIDQLHAAGHINLEQAEAEKIIHS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=156747 SanJ4206_RS01055 WP_003028470.1 208638..209579(+) (comYA) [Streptococcus anginosus strain J4206]
ATGGTTCAAAATATTGCACAGGCTATTATTTGCCAAGCTAAGGAAGAACAGGCTCAGGATATTTACGTTGTTCCAAAAGA
AAATATGTATGAGCTATACATGCGAATTGGCGATGAACGGCGTTTCATCCAACAGTATGCATTTGAAGAGATGGCAGCAG
TAATTAGTCATTTCAAGTTTACCGCTGGAATGAATGTCGGCGAAAAACGTAGAAGCCAGTTAGGATCTTGTGATTATCAA
TATGGTGACAAGCAAACGTCACTACGACTGTCAACAGTAGGGGATTATCGTGGATATGAAAGTCTGGTGATTCGTTTATT
ACATGATGAAGAGGCAGAGTTGAAGTTTTGGTTTGCTCAAATCCCAGAGTTAAAAGAACGCTTCAAACAGCGAGGGCTTT
ATCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACAACTCTCATGCACCAACTCGCCCAAGAGCGTTTTGCTGGTCAGCAA
ATCATGTCCATTGAAGACCCTGTTGAAATCAAGCAGCCTAGCATGTTACAGTTGCAATTAAATGAAGCGATTGGTTTGAC
TTATGAAAATTTGATTAAACTTTCTCTACGGCACCGACCGGATTTGCTAATCATCGGAGAAATTCGAGATGGGGAGACAG
CACGGGCTGTTGTCCGAGCTAGCTTGACAGGAGTGACTGTCTTTTCAACCATTCATGCTAAAAGCGTACGAGGTGTCTAT
GAACGGTTGTTGGAATTGGGAGTGACAGAAGCCGAGCTGAAAATTGTCTTGCAAGGGATTTGTTACCAACGTTTAATTGC
AAAAGGAGGAATAGTGGATTTTGTCAGTGAAAAGTATCAAGAACACGAGCCAATCGACTGGAATAGGCAGATTGATCAGC
TTCATGCAGCAGGACATATCAATCTTGAACAAGCAGAAGCGGAAAAAATTATCCACAGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

83.226

99.042

0.824
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

75.719

100

0.757
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae D39

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae R6

75.399

100

0.754
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

75.399

100

0.754
  comYA Streptococcus mutans UA159

64.952

99.361

0.645
  comYA Streptococcus mutans UA140

64.952

99.361

0.645
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.581

99.042

0.62
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54
  comGA Latilactobacillus sakei subsp. sakei 23K

42.857

84.984

0.364

Multiple sequence alignment