Detailed information NTG1170326

Bioinformatically predicted

Overview

• Name: comX/sigX/comX2/sigX2
• Type: Regulator
• Locus tag: ACLV7D_RS00070
• Genome accession: NZ_OZ217345
• Coordinates: 14256..14735 (+)
• Length: 159 a.a.
• NCBI ID: WP_112445392.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis F22
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	14833..15999	14256..14735	flank	98

Gene organization within MGE regions

Location: 14256..15999

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7D_RS00070 (SMIF22_00140)	comX/sigX/comX2/sigX2	14256..14735 (+)	480	WP_112445392.1	sigma-70 family RNA polymerase sigma factor	Regulator
ACLV7D_RS00075 (SMIF22_00150)	-	14833..15999 (-)	1167	WP_218764575.1	IS30 family transposase	-

Sequence

Protein

• Length: 159 a.a.
• Molecular weight: 20065.74 Da
• Isoelectric Point: 6.7595

>NTDB_id=1170326 ACLV7D_RS00070 WP_112445392.1 14256..14735(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis isolate S. mitis F22]
MIKELYEEVQGIVYKCRNEYYLHLWELSDWDQEGMICLHELISREEELAEDIPRLRKYFKTKFRNRILDYLRKQESHKRR
YDKELYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQTKDQQEELERILRNERFRGRQRVLRDLRIVFKEFDIRTH

Nucleotide

• Length: 480 bp

>NTDB_id=1170326 ACLV7D_RS00070 WP_112445392.1 14256..14735(+) (comX/sigX/comX2/sigX2) [Streptococcus mitis isolate S. mitis F22]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGAATTGTATACAAGTGTAGAAATGAATATTACCTTCATTTATGGGAGTT
ATCGGACTGGGATCAAGAGGGAATGATATGTCTACATGAATTGATTAGTAGAGAAGAAGAGCTGGCAGAAGATATTCCTC
GTTTACGTAAATATTTCAAAACAAAATTCCGGAATCGAATTTTAGATTATCTCCGTAAGCAAGAAAGTCACAAACGGAGA
TATGATAAAGAGCTTTATGAAGAAGTGGGTGAGATAAGTCATCGTATAAGTGAGGGCGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGGGATTATAGAAACAAACAAACTAAAGATCAACAAGAAGAACTAGAACGCATCTTAAGAA
ATGAACGATTCCGAGGTCGTCAAAGAGTATTAAGAGACTTACGTATTGTGTTTAAAGAGTTTGACATCCGTACCCATTAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	92.453	100	0.925
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	91.195	100	0.912
comX/comX2	Streptococcus pneumoniae Rx1	91.195	100	0.912
comX/comX1	Streptococcus pneumoniae Rx1	91.195	100	0.912
comX/comX2	Streptococcus pneumoniae D39	91.195	100	0.912
comX/comX1	Streptococcus pneumoniae D39	91.195	100	0.912
comX/comX1	Streptococcus pneumoniae R6	91.195	100	0.912
comX/comX2	Streptococcus pneumoniae R6	91.195	100	0.912
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	91.195	100	0.912
comX/comX1	Streptococcus pneumoniae TIGR4	90.566	100	0.906
comX/comX2	Streptococcus pneumoniae TIGR4	90.566	100	0.906
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	91.139	99.371	0.906
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	46.154	98.113	0.453
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	46.154	98.113	0.453
comX/sigX	Streptococcus mutans UA159	45.333	94.34	0.428
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42.763	95.597	0.409
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42.763	95.597	0.409
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	43.624	93.711	0.409
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	43.624	93.711	0.409
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	43.624	93.711	0.409
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	43.624	93.711	0.409
comX/sigX	Streptococcus suis D9	43.046	94.969	0.409
comX/sigX	Streptococcus suis isolate S10	43.046	94.969	0.409
comX/sigX	Streptococcus suis P1/7	43.046	94.969	0.409
comX	Streptococcus salivarius SK126	38.667	94.34	0.365