Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   ACLV7H_RS01065 Genome accession   NZ_OZ217340
Coordinates   186402..186725 (+) Length   107 a.a.
NCBI ID   WP_220107351.1    Uniprot ID   -
Organism   Streptococcus oralis isolate S. oralis A22     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 181402..191725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS01045 (SORA22_02050) nagA 182764..183915 (+) 1152 WP_411866133.1 N-acetylglucosamine-6-phosphate deacetylase -
  ACLV7H_RS01050 (SORA22_02060) - 184067..184432 (+) 366 WP_000286396.1 DUF1033 family protein -
  ACLV7H_RS01055 (SORA22_02070) comGA/cglA/cilD 184495..185436 (+) 942 WP_042768810.1 competence type IV pilus ATPase ComGA Machinery gene
  ACLV7H_RS01060 (SORA22_02080) comGB/cglB 185384..186400 (+) 1017 WP_411867062.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACLV7H_RS01065 (SORA22_02090) comGC/cglC 186402..186725 (+) 324 WP_220107351.1 competence type IV pilus major pilin ComGC Machinery gene
  ACLV7H_RS01070 (SORA22_02100) comGD/cglD 186688..187122 (+) 435 WP_411866134.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACLV7H_RS01075 (SORA22_02110) comGE/cglE 187085..187387 (+) 303 WP_045591925.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACLV7H_RS01080 (SORA22_02120) comGF/cglF 187350..187811 (+) 462 WP_045591923.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACLV7H_RS01085 (SORA22_02130) comGG/cglG 187789..188202 (+) 414 WP_411866135.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACLV7H_RS01090 (SORA22_02140) - 188235..188825 (+) 591 WP_411866136.1 class I SAM-dependent methyltransferase -
  ACLV7H_RS01095 (SORA22_02150) comYH 188884..189837 (+) 954 WP_411866137.1 class I SAM-dependent methyltransferase Machinery gene
  ACLV7H_RS01100 (SORA22_02160) - 189888..191078 (+) 1191 WP_411866138.1 acetate kinase -
  ACLV7H_RS01105 (SORA22_02170) rnpA 191228..191599 (+) 372 WP_084848875.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 11884.04 Da        Isoelectric Point: 10.1648

>NTDB_id=1169928 ACLV7H_RS01065 WP_220107351.1 186402..186725(+) (comGC/cglC) [Streptococcus oralis isolate S. oralis A22]
MKKFMTKLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVDDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITAEQAKAYKDYHAKQKTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=1169928 ACLV7H_RS01065 WP_220107351.1 186402..186725(+) (comGC/cglC) [Streptococcus oralis isolate S. oralis A22]
ATGAAAAAATTCATGACAAAACTAAAAAAAGCTAAGGTTAAAGCTTTCACTTTGGTAGAAATGTTAGTGGTCTTGCTTAT
CATCAGTGTTCTTCTCTTGCTCTTTGTGCCCAATTTGACCAAGCAAAAGGATGCCGTAGATGATAAAGGAAAAGCTGCTG
TTGTCAAGGTTGTGGAAAGCCAGGCAGAGCTCTATAGTTTGGACAAGAATGAAGATGCCAGCCTCAGCAAATTACAAGCG
GACGGTCGTATTACAGCTGAGCAAGCTAAAGCTTATAAAGACTACCATGCAAAGCAAAAAACAAGTCAAACTGTTGCAGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

93.458

100

0.935

  comGC/cglC Streptococcus mitis SK321

90.909

92.523

0.841

  comGC/cglC Streptococcus pneumoniae R6

88.889

92.523

0.822

  comGC/cglC Streptococcus pneumoniae Rx1

88.889

92.523

0.822

  comGC/cglC Streptococcus pneumoniae D39

88.889

92.523

0.822

  comGC/cglC Streptococcus pneumoniae TIGR4

87.879

92.523

0.813

  comYC Streptococcus gordonii str. Challis substr. CH1

68.571

98.131

0.673

  comYC Streptococcus mutans UA140

70.103

90.654

0.636

  comYC Streptococcus mutans UA159

70.103

90.654

0.636

  comYC Streptococcus suis isolate S10

68.182

82.243

0.561

  comGC Lactococcus lactis subsp. cremoris KW2

56.863

95.327

0.542


Multiple sequence alignment