Detailed information NTG1169931

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: ACLV7H_RS01080
• Genome accession: NZ_OZ217340
• Coordinates: 187350..187811 (+)
• Length: 153 a.a.
• NCBI ID: WP_045591923.1
• Uniprot ID: -
• Organism: Streptococcus oralis isolate S. oralis A22
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 182350..192811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7H_RS01045 (SORA22_02050)	nagA	182764..183915 (+)	1152	WP_411866133.1	N-acetylglucosamine-6-phosphate deacetylase	-
ACLV7H_RS01050 (SORA22_02060)	-	184067..184432 (+)	366	WP_000286396.1	DUF1033 family protein	-
ACLV7H_RS01055 (SORA22_02070)	comGA/cglA/cilD	184495..185436 (+)	942	WP_042768810.1	competence type IV pilus ATPase ComGA	Machinery gene
ACLV7H_RS01060 (SORA22_02080)	comGB/cglB	185384..186400 (+)	1017	WP_411867062.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACLV7H_RS01065 (SORA22_02090)	comGC/cglC	186402..186725 (+)	324	WP_220107351.1	competence type IV pilus major pilin ComGC	Machinery gene
ACLV7H_RS01070 (SORA22_02100)	comGD/cglD	186688..187122 (+)	435	WP_411866134.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACLV7H_RS01075 (SORA22_02110)	comGE/cglE	187085..187387 (+)	303	WP_045591925.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACLV7H_RS01080 (SORA22_02120)	comGF/cglF	187350..187811 (+)	462	WP_045591923.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACLV7H_RS01085 (SORA22_02130)	comGG/cglG	187789..188202 (+)	414	WP_411866135.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACLV7H_RS01090 (SORA22_02140)	-	188235..188825 (+)	591	WP_411866136.1	class I SAM-dependent methyltransferase	-
ACLV7H_RS01095 (SORA22_02150)	comYH	188884..189837 (+)	954	WP_411866137.1	class I SAM-dependent methyltransferase	Machinery gene
ACLV7H_RS01100 (SORA22_02160)	-	189888..191078 (+)	1191	WP_411866138.1	acetate kinase	-
ACLV7H_RS01105 (SORA22_02170)	rnpA	191228..191599 (+)	372	WP_084848875.1	ribonuclease P protein component	-
ACLV7H_RS01110 (SORA22_02180)	-	191574..192401 (+)	828	WP_411866139.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17821.43 Da
• Isoelectric Point: 9.7631

>NTDB_id=1169931 ACLV7H_RS01080 WP_045591923.1 187350..187811(+) (comGF/cglF) [Streptococcus oralis isolate S. oralis A22]
MVQRSYSTLKSSKVRAFTLLESLIALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELERSQFEKVEGN
RLYMKQDGKDVSIGKSKSDDFRKTDTSGRGYQPMVYGLKSAQITEENQLVRFRFQFQKGLEREFIYRVEKAKS

Nucleotide

• Length: 462 bp

>NTDB_id=1169931 ACLV7H_RS01080 WP_045591923.1 187350..187811(+) (comGF/cglF) [Streptococcus oralis isolate S. oralis A22]
ATGGTTCAGAGAAGTTACTCGACCTTAAAGAGCAGTAAGGTAAGAGCTTTCACTCTTTTAGAATCTCTGATTGCCCTTAT
CGTTATTAGCGGAGGCTTGCTCCTCTTTCAAGCCATGAGTCAGCTCCTCATTTCAGAAGTTCGTTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGATCAACTGGAGGCAGAGTTAGAGCGTTCGCAGTTTGAAAAGGTGGAAGGCAAT
CGCCTCTACATGAAACAGGATGGTAAGGATGTCTCTATAGGGAAGTCTAAATCGGATGATTTTCGAAAAACTGATACCAG
CGGACGGGGCTACCAACCCATGGTTTACGGACTCAAATCAGCTCAAATTACAGAGGAAAATCAATTGGTTCGCTTTCGTT
TCCAATTTCAAAAGGGTTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGCAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis SK321	90.196	100	0.902
comGF/cglF	Streptococcus mitis NCTC 12261	88.889	100	0.889
comGF/cglF	Streptococcus pneumoniae Rx1	86.928	100	0.869
comGF/cglF	Streptococcus pneumoniae D39	86.928	100	0.869
comGF/cglF	Streptococcus pneumoniae R6	86.928	100	0.869
comGF/cglF	Streptococcus pneumoniae TIGR4	86.928	100	0.869
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373