Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   ACLV7H_RS01060 Genome accession   NZ_OZ217340
Coordinates   185384..186400 (+) Length   338 a.a.
NCBI ID   WP_411867062.1    Uniprot ID   -
Organism   Streptococcus oralis isolate S. oralis A22     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 180384..191400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLV7H_RS01040 (SORA22_02040) - 180806..182623 (+) 1818 WP_411866132.1 acyltransferase family protein -
  ACLV7H_RS01045 (SORA22_02050) nagA 182764..183915 (+) 1152 WP_411866133.1 N-acetylglucosamine-6-phosphate deacetylase -
  ACLV7H_RS01050 (SORA22_02060) - 184067..184432 (+) 366 WP_000286396.1 DUF1033 family protein -
  ACLV7H_RS01055 (SORA22_02070) comGA/cglA/cilD 184495..185436 (+) 942 WP_042768810.1 competence type IV pilus ATPase ComGA Machinery gene
  ACLV7H_RS01060 (SORA22_02080) comGB/cglB 185384..186400 (+) 1017 WP_411867062.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACLV7H_RS01065 (SORA22_02090) comGC/cglC 186402..186725 (+) 324 WP_220107351.1 competence type IV pilus major pilin ComGC Machinery gene
  ACLV7H_RS01070 (SORA22_02100) comGD/cglD 186688..187122 (+) 435 WP_411866134.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACLV7H_RS01075 (SORA22_02110) comGE/cglE 187085..187387 (+) 303 WP_045591925.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACLV7H_RS01080 (SORA22_02120) comGF/cglF 187350..187811 (+) 462 WP_045591923.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACLV7H_RS01085 (SORA22_02130) comGG/cglG 187789..188202 (+) 414 WP_411866135.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACLV7H_RS01090 (SORA22_02140) - 188235..188825 (+) 591 WP_411866136.1 class I SAM-dependent methyltransferase -
  ACLV7H_RS01095 (SORA22_02150) comYH 188884..189837 (+) 954 WP_411866137.1 class I SAM-dependent methyltransferase Machinery gene
  ACLV7H_RS01100 (SORA22_02160) - 189888..191078 (+) 1191 WP_411866138.1 acetate kinase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38571.71 Da        Isoelectric Point: 9.6792

>NTDB_id=1169927 ACLV7H_RS01060 WP_411867062.1 185384..186400(+) (comGB/cglB) [Streptococcus oralis isolate S. oralis A22]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVTQMHQGLSQGKSFSEMMNSLGFSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQELAQALQNGREFSQTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEVFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=1169927 ACLV7H_RS01060 WP_411867062.1 185384..186400(+) (comGB/cglB) [Streptococcus oralis isolate S. oralis A22]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACCCTGTTTAA
CAACCTCTTCTCCAGTGGCTTTCATTTGGTGGAAATTATTTCTTTCTTGGGCAGAAGTGCCCTGCTGGAAAAGGACTATG
TGACCCAGATGCACCAAGGCTTATCTCAGGGGAAATCTTTCTCAGAAATGATGAACAGCTTGGGTTTTTCAAGTGCCATC
GTGACCCAATTATCCCTAGCTGAGGTTCATGGGAATCTTCATCTGAGTCTGGGGAAGATAGAAGAATATCTGGACAATCT
GGCTAAGGTCAAGAAAAAATTAATCGAAGTGGCGACTTATCCCCTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG
GGTTGAGAAACTATTTGCTGCCTCAACTGGACAGTAGCAATATCGCCACTCAAATCATCGGCAATCTGCCACAAATTTTT
CTGGGGCTAGTGTTGGTTTGCTCTCTGTCTCTACTTTTAGCCCTCACTTTCTACAAAAGAAGTTCCAAGATGCGGGTCTT
CTCGATGTTGGCACGGATTCCCTTTCTGGGAATCTTTGTCCAGACTTATCTGACGGCCTATTACGCGCGTGAATGGGGCA
ATATGATTTCACAGGGGATGGAGCTGACGCAGATTTTTCAGATCATGCAGGAACAGGGTTCTCAGCTCTTTAAAGAAATC
GGTCAAGAACTGGCTCAAGCCCTGCAAAATGGCCGCGAATTTTCTCAAACCATAGCGACCTATCCTTTCTTTAAAAAGGA
GTTGAGTCTCATCATCGAGTATGGAGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGTCTTTTTTACCCGAGTCAACCGCACCATGAACTTAGTACAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTTATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

93.787

100

0.938
  comGB/cglB Streptococcus mitis NCTC 12261

92.899

100

0.929
  comGB/cglB Streptococcus pneumoniae Rx1

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae D39

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae R6

91.124

100

0.911
  comGB/cglB Streptococcus pneumoniae TIGR4

91.124

100

0.911
  comYB Streptococcus gordonii str. Challis substr. CH1

73.512

99.408

0.731
  comYB Streptococcus mutans UA140

58.934

94.379

0.556
  comYB Streptococcus mutans UA159

58.934

94.379

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

52.071

100

0.521

Multiple sequence alignment