Detailed information NTG1147165

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: CKV83_RS11065
• Genome accession: NZ_LT906439
• Coordinates: 2357604..2357906 (+)
• Length: 100 a.a.
• NCBI ID: WP_018374188.1
• Uniprot ID: A0A239T2X4
• Organism: Streptococcus merionis strain NCTC13788
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2352604..2362906

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKV83_RS11035 (SAMEA4412692_02205)	-	2352691..2353332 (+)	642	WP_018374182.1	amino acid ABC transporter permease	-
CKV83_RS11040 (SAMEA4412692_02206)	-	2353342..2353974 (+)	633	WP_018374183.1	amino acid ABC transporter ATP-binding protein	-
CKV83_RS11045 (SAMEA4412692_02207)	-	2354059..2354892 (+)	834	WP_018374184.1	amino acid ABC transporter substrate-binding protein	-
CKV83_RS11050 (SAMEA4412692_02208)	-	2355221..2355577 (+)	357	WP_018374185.1	DUF1033 family protein	-
CKV83_RS11055 (SAMEA4412692_02209)	comYA	2355699..2356640 (+)	942	WP_018374186.1	competence type IV pilus ATPase ComGA	Machinery gene
CKV83_RS11060 (SAMEA4412692_02210)	comYB	2356570..2357604 (+)	1035	WP_018374187.1	competence type IV pilus assembly protein ComGB	Machinery gene
CKV83_RS11065 (SAMEA4412692_02211)	comGC/cglC	2357604..2357906 (+)	303	WP_018374188.1	competence type IV pilus major pilin ComGC	Machinery gene
CKV83_RS11070 (SAMEA4412692_02212)	comGD	2357866..2358312 (+)	447	WP_331711864.1	competence type IV pilus minor pilin ComGD	-
CKV83_RS11075 (SAMEA4412692_02213)	comGE	2358305..2358577 (+)	273	WP_018374190.1	competence type IV pilus minor pilin ComGE	-
CKV83_RS11080 (SAMEA4412692_02214)	comGF	2358555..2358998 (+)	444	WP_018374191.1	competence type IV pilus minor pilin ComGF	-
CKV83_RS11085 (SAMEA4412692_02215)	comGG	2358976..2359503 (+)	528	WP_018374192.1	competence type IV pilus minor pilin ComGG	-
CKV83_RS11090 (SAMEA4412692_02216)	comYH	2359523..2360476 (+)	954	WP_026217003.1	class I SAM-dependent methyltransferase	Machinery gene
CKV83_RS11095 (SAMEA4412692_02217)	-	2360533..2361723 (+)	1191	WP_018374194.1	acetate kinase	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11013.96 Da
• Isoelectric Point: 9.4268

>NTDB_id=1147165 CKV83_RS11065 WP_018374188.1 2357604..2357906(+) (comGC/cglC) [Streptococcus merionis strain NCTC13788]
MKKLKEKLLKATVKGFTLVEMLIVLLIISVLLLLFVPNLTKQKDSVTKTGNQAVVKVVESQKELYAVANPTAGEPSAETL
ANEGYITNEQLETYNKHVGQ

Nucleotide

• Length: 303 bp

>NTDB_id=1147165 CKV83_RS11065 WP_018374188.1 2357604..2357906(+) (comGC/cglC) [Streptococcus merionis strain NCTC13788]
ATGAAAAAATTAAAAGAAAAACTATTGAAAGCTACTGTAAAAGGTTTCACACTTGTGGAGATGTTAATTGTCCTTCTAAT
CATCAGTGTTTTGCTCTTACTGTTTGTACCTAATTTGACCAAGCAGAAAGATAGCGTGACTAAGACAGGAAATCAGGCTG
TTGTCAAGGTTGTTGAAAGCCAGAAAGAGCTCTATGCAGTGGCCAATCCTACCGCTGGAGAGCCAAGTGCAGAGACTTTG
GCAAATGAAGGGTATATCACGAATGAGCAACTGGAAACCTATAACAAACACGTTGGTCAGTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (13-34)

3D structure

• AlphaFold DB: A0A239T2X4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis SK321	58	100	0.58
comGC/cglC	Streptococcus mitis NCTC 12261	58.763	97	0.57
comGC/cglC	Streptococcus pneumoniae TIGR4	57.732	97	0.56
comGC/cglC	Streptococcus pneumoniae Rx1	57.732	97	0.56
comGC/cglC	Streptococcus pneumoniae D39	57.732	97	0.56
comGC/cglC	Streptococcus pneumoniae R6	57.732	97	0.56
comYC	Streptococcus gordonii str. Challis substr. CH1	58.511	94	0.55
comYC	Streptococcus mutans UA140	55	100	0.55
comYC	Streptococcus mutans UA159	55	100	0.55
comYC	Streptococcus suis isolate S10	57.955	88	0.51
comGC	Lactococcus lactis subsp. cremoris KW2	51.064	94	0.48
comGC	Staphylococcus aureus MW2	48.276	87	0.42
comGC	Staphylococcus aureus N315	48.276	87	0.42