Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   CKV83_RS11055 Genome accession   NZ_LT906439
Coordinates   2355699..2356640 (+) Length   313 a.a.
NCBI ID   WP_018374186.1    Uniprot ID   -
Organism   Streptococcus merionis strain NCTC13788     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2350699..2361640
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV83_RS11035 (SAMEA4412692_02205) - 2352691..2353332 (+) 642 WP_018374182.1 amino acid ABC transporter permease -
  CKV83_RS11040 (SAMEA4412692_02206) - 2353342..2353974 (+) 633 WP_018374183.1 amino acid ABC transporter ATP-binding protein -
  CKV83_RS11045 (SAMEA4412692_02207) - 2354059..2354892 (+) 834 WP_018374184.1 amino acid ABC transporter substrate-binding protein -
  CKV83_RS11050 (SAMEA4412692_02208) - 2355221..2355577 (+) 357 WP_018374185.1 DUF1033 family protein -
  CKV83_RS11055 (SAMEA4412692_02209) comYA 2355699..2356640 (+) 942 WP_018374186.1 competence type IV pilus ATPase ComGA Machinery gene
  CKV83_RS11060 (SAMEA4412692_02210) comYB 2356570..2357604 (+) 1035 WP_018374187.1 competence type IV pilus assembly protein ComGB Machinery gene
  CKV83_RS11065 (SAMEA4412692_02211) comGC/cglC 2357604..2357906 (+) 303 WP_018374188.1 competence type IV pilus major pilin ComGC Machinery gene
  CKV83_RS11070 (SAMEA4412692_02212) comGD 2357866..2358312 (+) 447 WP_331711864.1 competence type IV pilus minor pilin ComGD -
  CKV83_RS11075 (SAMEA4412692_02213) comGE 2358305..2358577 (+) 273 WP_018374190.1 competence type IV pilus minor pilin ComGE -
  CKV83_RS11080 (SAMEA4412692_02214) comGF 2358555..2358998 (+) 444 WP_018374191.1 competence type IV pilus minor pilin ComGF -
  CKV83_RS11085 (SAMEA4412692_02215) comGG 2358976..2359503 (+) 528 WP_018374192.1 competence type IV pilus minor pilin ComGG -
  CKV83_RS11090 (SAMEA4412692_02216) comYH 2359523..2360476 (+) 954 WP_026217003.1 class I SAM-dependent methyltransferase Machinery gene

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35822.61 Da        Isoelectric Point: 6.3990

>NTDB_id=1147163 CKV83_RS11055 WP_018374186.1 2355699..2356640(+) (comYA) [Streptococcus merionis strain NCTC13788]
MVQERARQLIADAVKERISDLYFLPKDTHFELYLRKNDERRFEGEFPYDEMQAIVGHFKFVSGMNVGEKRRSQLGSCNYD
YGEGTISLRLSTVGDYKGHESMVIRLIYDLDSDLSFWFESVRKLADDVKGRGLYLFSGPVGSGKTSLMYHLARQRFQGQQ
VITIEDPVEIKQEDMLQLQLNETIGSTYDELIKLSLRHRPDLLIIGEIRDSQTARAVMRASLTGATVFSTIHAKSISGVY
DRLIELGVSPEELKNSLQGIYYQRLLAGGGVVDFANQNFEKYQPTKWNQQIDQLFAAGHLSERQWQSEKIKTA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1147163 CKV83_RS11055 WP_018374186.1 2355699..2356640(+) (comYA) [Streptococcus merionis strain NCTC13788]
ATGGTACAAGAACGTGCAAGGCAACTAATTGCAGACGCTGTCAAAGAGCGGATTAGCGATCTTTATTTTTTACCGAAGGA
TACACACTTTGAGCTCTATTTGCGGAAAAATGATGAGCGACGGTTTGAAGGAGAATTTCCCTATGATGAAATGCAGGCGA
TTGTAGGGCATTTTAAGTTTGTCTCAGGGATGAATGTTGGAGAGAAGCGTCGCAGTCAGCTGGGTTCCTGTAATTACGAT
TATGGAGAGGGGACGATTTCTTTGCGCCTATCAACGGTAGGAGATTACAAGGGGCACGAAAGTATGGTCATTCGCCTTAT
TTATGATTTGGATTCAGACTTATCCTTCTGGTTTGAAAGTGTCCGCAAATTAGCTGATGATGTGAAAGGCAGAGGGCTAT
ACCTTTTTTCGGGTCCAGTTGGGAGTGGCAAAACCTCTCTCATGTACCATCTAGCCCGTCAACGTTTTCAAGGACAGCAA
GTCATTACGATTGAAGATCCTGTGGAAATCAAACAAGAAGATATGTTGCAGCTTCAGCTCAACGAAACGATCGGCTCGAC
CTACGATGAATTGATAAAATTATCCCTGCGTCACAGGCCAGATTTGCTCATCATTGGCGAAATTCGAGACAGTCAGACCG
CGCGTGCAGTCATGAGAGCCAGTTTGACAGGTGCAACCGTCTTTTCTACCATTCACGCCAAATCAATCAGTGGGGTTTAT
GACCGCTTGATCGAATTGGGCGTCAGCCCCGAAGAGCTCAAAAACAGCCTTCAGGGCATTTATTATCAGCGCTTATTAGC
AGGAGGAGGTGTGGTAGATTTTGCAAATCAAAACTTTGAGAAGTATCAACCGACCAAGTGGAACCAGCAAATTGATCAGC
TTTTTGCAGCAGGACATCTCTCTGAGCGCCAATGGCAAAGCGAAAAAATTAAAACTGCTTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

66.346

99.681

0.661
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.194

99.042

0.636
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.871

99.042

0.633
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.871

99.042

0.633
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.871

99.042

0.633
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.871

99.042

0.633
  comYA Streptococcus mutans UA159

62.821

99.681

0.626
  comYA Streptococcus mutans UA140

62.821

99.681

0.626
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

59.486

99.361

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

54.984

99.361

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

41.544

86.901

0.361

Multiple sequence alignment