Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   CKV83_RS11060 Genome accession   NZ_LT906439
Coordinates   2356570..2357604 (+) Length   344 a.a.
NCBI ID   WP_018374187.1    Uniprot ID   -
Organism   Streptococcus merionis strain NCTC13788     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2351570..2362604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV83_RS11035 (SAMEA4412692_02205) - 2352691..2353332 (+) 642 WP_018374182.1 amino acid ABC transporter permease -
  CKV83_RS11040 (SAMEA4412692_02206) - 2353342..2353974 (+) 633 WP_018374183.1 amino acid ABC transporter ATP-binding protein -
  CKV83_RS11045 (SAMEA4412692_02207) - 2354059..2354892 (+) 834 WP_018374184.1 amino acid ABC transporter substrate-binding protein -
  CKV83_RS11050 (SAMEA4412692_02208) - 2355221..2355577 (+) 357 WP_018374185.1 DUF1033 family protein -
  CKV83_RS11055 (SAMEA4412692_02209) comYA 2355699..2356640 (+) 942 WP_018374186.1 competence type IV pilus ATPase ComGA Machinery gene
  CKV83_RS11060 (SAMEA4412692_02210) comYB 2356570..2357604 (+) 1035 WP_018374187.1 competence type IV pilus assembly protein ComGB Machinery gene
  CKV83_RS11065 (SAMEA4412692_02211) comGC/cglC 2357604..2357906 (+) 303 WP_018374188.1 competence type IV pilus major pilin ComGC Machinery gene
  CKV83_RS11070 (SAMEA4412692_02212) comGD 2357866..2358312 (+) 447 WP_331711864.1 competence type IV pilus minor pilin ComGD -
  CKV83_RS11075 (SAMEA4412692_02213) comGE 2358305..2358577 (+) 273 WP_018374190.1 competence type IV pilus minor pilin ComGE -
  CKV83_RS11080 (SAMEA4412692_02214) comGF 2358555..2358998 (+) 444 WP_018374191.1 competence type IV pilus minor pilin ComGF -
  CKV83_RS11085 (SAMEA4412692_02215) comGG 2358976..2359503 (+) 528 WP_018374192.1 competence type IV pilus minor pilin ComGG -
  CKV83_RS11090 (SAMEA4412692_02216) comYH 2359523..2360476 (+) 954 WP_026217003.1 class I SAM-dependent methyltransferase Machinery gene
  CKV83_RS11095 (SAMEA4412692_02217) - 2360533..2361723 (+) 1191 WP_018374194.1 acetate kinase -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 38866.27 Da        Isoelectric Point: 9.0826

>NTDB_id=1147164 CKV83_RS11060 WP_018374187.1 2356570..2357604(+) (comYB) [Streptococcus merionis strain NCTC13788]
MISFLQQDISLSANGKAKKLKLLRQKKVIALFNNLFSSGFNLTEIIDFLKRSQLLSDPYTDVMQEGLVAGQPFSAIMQRL
GFSDQVVTQLSLAELHGNLSLCLEKIEAYLSQVLVVRKKLIEVATYPVILLGFLVLLMLGLKNYLLPQLSDGNLATVLIG
HFPTIFLGSFVLLLVAILGLKLWLKQTAHLPVVRFLAKLPGIGRLVRLYLTGYYAREWGNLIGQGLEMTQILNIMVQQPS
RLFAEIGQDMLKSLSNGQAFHDKVKDYSFFEKELSLMIEYGEAKSKLGQELDIYAQDCWDRFFTKVNQLMQLIQPLIFIF
VALIIVLIYAAMLLPIYNNMEVPI

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=1147164 CKV83_RS11060 WP_018374187.1 2356570..2357604(+) (comYB) [Streptococcus merionis strain NCTC13788]
TTGATCAGCTTTTTGCAGCAGGACATCTCTCTGAGCGCCAATGGCAAAGCGAAAAAATTAAAACTGCTTAGGCAGAAGAA
AGTCATTGCGCTTTTTAACAATCTTTTCAGCTCAGGTTTTAATCTGACAGAGATTATTGATTTTCTAAAGCGAAGTCAAT
TGCTGAGCGATCCGTATACAGATGTTATGCAAGAAGGTCTTGTAGCTGGTCAACCTTTCTCGGCCATTATGCAAAGGCTG
GGCTTTTCAGATCAAGTGGTGACCCAACTCAGTTTGGCCGAACTTCATGGCAATCTTTCTCTATGTTTGGAGAAAATAGA
GGCGTATCTGAGTCAGGTTCTGGTGGTTCGAAAAAAACTGATTGAGGTGGCCACTTATCCAGTAATCCTCCTAGGATTTT
TAGTGTTACTGATGCTAGGGTTGAAAAATTACCTTTTACCCCAATTGTCCGATGGCAACCTTGCGACGGTGTTGATTGGT
CACTTTCCGACAATCTTTTTAGGCAGTTTTGTTTTACTGTTAGTCGCAATTCTTGGATTAAAACTTTGGCTAAAACAGAC
TGCTCATCTACCAGTGGTGCGCTTTTTAGCGAAACTCCCTGGAATTGGTCGCCTAGTCCGCCTCTATCTGACCGGCTACT
ATGCTAGAGAATGGGGAAATTTGATTGGTCAGGGACTTGAGATGACCCAAATCTTAAATATCATGGTCCAGCAGCCGTCC
CGATTGTTTGCGGAAATTGGTCAGGACATGCTCAAGAGCCTATCCAATGGTCAGGCTTTTCACGATAAGGTCAAGGACTA
TTCTTTCTTTGAAAAGGAGTTGTCTCTCATGATTGAATACGGTGAAGCCAAGTCTAAGTTAGGTCAAGAATTGGACATCT
ATGCTCAGGATTGCTGGGATCGTTTCTTTACCAAGGTCAATCAACTTATGCAGCTGATTCAGCCGCTTATCTTTATTTTT
GTTGCTTTGATTATTGTGCTCATTTACGCAGCCATGCTCTTACCGATTTATAATAATATGGAGGTTCCTATATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(31-147)

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

64.327

99.419

0.64
  comYB Streptococcus mutans UA159

60.641

99.709

0.605
  comYB Streptococcus mutans UA140

60.641

99.709

0.605
  comGB/cglB Streptococcus mitis NCTC 12261

58.806

97.384

0.573
  comGB/cglB Streptococcus pneumoniae TIGR4

57.91

97.384

0.564
  comGB/cglB Streptococcus pneumoniae Rx1

57.91

97.384

0.564
  comGB/cglB Streptococcus mitis SK321

57.91

97.384

0.564
  comGB/cglB Streptococcus pneumoniae D39

57.91

97.384

0.564
  comGB/cglB Streptococcus pneumoniae R6

57.91

97.384

0.564
  comGB Lactococcus lactis subsp. cremoris KW2

51.917

98.547

0.512

Multiple sequence alignment