Detailed information
Bioinformatically predicted
Overview
| Name | pilU | Type | Machinery gene |
| Locus tag | A8Q77_RS03325 | Genome accession | NZ_LT571436 |
| Coordinates | 739135..740268 (-) | Length | 377 a.a. |
| NCBI ID | WP_004285269.1 | Uniprot ID | - |
| Organism | Neisseria weaveri strain NCTC13585 | ||
| Function | assembly of type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 731733..803562 | 739135..740268 | within | 0 |
Gene organization within MGE regions
Location: 731733..803562
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A8Q77_RS03300 (SAMEA3174300_00657) | efp | 731787..732347 (-) | 561 | WP_004283334.1 | elongation factor P | - |
| A8Q77_RS03305 (SAMEA3174300_00658) | earP | 732396..733553 (-) | 1158 | WP_064130427.1 | elongation factor P maturation arginine rhamnosyltransferase EarP | - |
| A8Q77_RS03310 (SAMEA3174300_00659) | gyrA | 734176..736923 (+) | 2748 | WP_004283331.1 | DNA gyrase subunit A | - |
| A8Q77_RS03315 | - | 736934..737278 (+) | 345 | WP_064130428.1 | hypothetical protein | - |
| A8Q77_RS03320 (SAMEA3174300_00660) | dld | 737367..739058 (+) | 1692 | WP_004285270.1 | D-lactate dehydrogenase | - |
| A8Q77_RS03325 (SAMEA3174300_00661) | pilU | 739135..740268 (-) | 1134 | WP_004285269.1 | PilT/PilU family type 4a pilus ATPase | Machinery gene |
| A8Q77_RS03330 (SAMEA3174300_00662) | - | 740442..741161 (+) | 720 | WP_004285268.1 | 5'-methylthioadenosine/adenosylhomocysteine nucleosidase | - |
| A8Q77_RS03335 (SAMEA3174300_00663) | recD | 741217..742974 (+) | 1758 | WP_064130429.1 | exodeoxyribonuclease V subunit alpha | Machinery gene |
| A8Q77_RS03340 (SAMEA3174300_00664) | ung | 743115..743774 (+) | 660 | WP_004285265.1 | uracil-DNA glycosylase | - |
| A8Q77_RS03345 (SAMEA3174300_00665) | recB | 743924..747544 (-) | 3621 | WP_064130430.1 | exodeoxyribonuclease V subunit beta | Machinery gene |
| A8Q77_RS03350 (SAMEA3174300_00666) | - | 747895..749658 (+) | 1764 | WP_064130431.1 | ShlB/FhaC/HecB family hemolysin secretion/activation protein | - |
| A8Q77_RS03355 (SAMEA3174300_00667) | - | 749812..758379 (+) | 8568 | WP_064130432.1 | hemagglutinin repeat-containing protein | - |
| A8Q77_RS03360 (SAMEA3174300_00668) | - | 758385..758672 (+) | 288 | WP_004285342.1 | barstar family protein | - |
| A8Q77_RS10735 | - | 758734..758976 (+) | 243 | WP_197671602.1 | hypothetical protein | - |
| A8Q77_RS03365 (SAMEA3174300_00669) | - | 759207..759563 (+) | 357 | WP_064130433.1 | hypothetical protein | - |
| A8Q77_RS03370 (SAMEA3174300_00670) | - | 759864..760640 (+) | 777 | WP_156503404.1 | VENN motif pre-toxin domain-containing protein | - |
| A8Q77_RS03375 (SAMEA3174300_00671) | - | 760637..760852 (+) | 216 | WP_064130435.1 | hypothetical protein | - |
| A8Q77_RS03380 (SAMEA3174300_00672) | - | 760932..762131 (+) | 1200 | WP_172795924.1 | VENN motif pre-toxin domain-containing protein | - |
| A8Q77_RS03385 (SAMEA3174300_00673) | - | 762165..762692 (+) | 528 | WP_107726135.1 | Imm42 family immunity protein | - |
| A8Q77_RS10885 | - | 763020..763244 (+) | 225 | WP_004283050.1 | hypothetical protein | - |
| A8Q77_RS03395 (SAMEA3174300_00674) | - | 763262..763756 (+) | 495 | WP_004283048.1 | immunity 42 family protein | - |
| A8Q77_RS03400 (SAMEA3174300_00675) | - | 763993..765618 (+) | 1626 | WP_064130437.1 | VENN motif pre-toxin domain-containing protein | - |
| A8Q77_RS03405 (SAMEA3174300_00676) | - | 765639..766142 (+) | 504 | WP_040670001.1 | hypothetical protein | - |
| A8Q77_RS03410 (SAMEA3174300_00677) | - | 766265..766708 (+) | 444 | WP_004284764.1 | hypothetical protein | - |
| A8Q77_RS03415 (SAMEA3174300_00678) | - | 766708..767061 (+) | 354 | WP_082887994.1 | DUF3969 family protein | - |
| A8Q77_RS03420 (SAMEA3174300_00679) | - | 767164..768477 (+) | 1314 | WP_172795925.1 | VENN motif pre-toxin domain-containing protein | - |
| A8Q77_RS03425 (SAMEA3174300_00680) | - | 768474..768914 (+) | 441 | WP_107855378.1 | Imm42 family immunity protein | - |
| A8Q77_RS03430 (SAMEA3174300_00681) | - | 769046..769699 (-) | 654 | WP_064130439.1 | IS1595 family transposase | - |
| A8Q77_RS03435 | - | 769714..770040 (+) | 327 | WP_036494199.1 | hypothetical protein | - |
| A8Q77_RS10535 | - | 770811..771053 (+) | 243 | WP_156503406.1 | hypothetical protein | - |
| A8Q77_RS03445 (SAMEA3174300_00682) | - | 771034..771471 (+) | 438 | WP_036494200.1 | hypothetical protein | - |
| A8Q77_RS10740 (SAMEA3174300_00683) | - | 771660..773078 (+) | 1419 | WP_197671603.1 | VENN motif pre-toxin domain-containing protein | - |
| A8Q77_RS03455 (SAMEA3174300_00684) | - | 773078..773530 (+) | 453 | WP_004283042.1 | hypothetical protein | - |
| A8Q77_RS10280 | - | 773549..773752 (-) | 204 | Protein_671 | IS1595 family transposase | - |
| A8Q77_RS03460 (SAMEA3174300_00685) | - | 774117..777434 (+) | 3318 | WP_231987957.1 | hemagglutinin repeat-containing protein | - |
| A8Q77_RS03465 (SAMEA3174300_00686) | - | 777457..777915 (+) | 459 | WP_064130442.1 | hypothetical protein | - |
| A8Q77_RS10540 (SAMEA3174300_00687) | - | 777945..778649 (+) | 705 | WP_064130443.1 | S-layer family protein | - |
| A8Q77_RS10290 | - | 778615..779274 (-) | 660 | Protein_675 | transposase | - |
| A8Q77_RS03485 (SAMEA3174300_00690) | - | 779701..780438 (+) | 738 | WP_004284756.1 | pirin family protein | - |
| A8Q77_RS03490 (SAMEA3174300_00691) | - | 780530..781138 (+) | 609 | WP_004284755.1 | nitroreductase family protein | - |
| A8Q77_RS03495 (SAMEA3174300_00692) | - | 781269..781952 (+) | 684 | WP_004284753.1 | hydrolase | - |
| A8Q77_RS03500 (SAMEA3174300_00693) | - | 782039..782260 (+) | 222 | WP_004284751.1 | DUF1427 family protein | - |
| A8Q77_RS03505 (SAMEA3174300_00694) | - | 782261..784153 (+) | 1893 | WP_064130445.1 | amidohydrolase | - |
| A8Q77_RS03510 (SAMEA3174300_00695) | - | 784314..785213 (+) | 900 | WP_064130446.1 | pirin family protein | - |
| A8Q77_RS03515 (SAMEA3174300_00696) | - | 785554..787161 (+) | 1608 | Protein_682 | MFS transporter | - |
| A8Q77_RS03520 (SAMEA3174300_00697) | - | 787427..787990 (-) | 564 | WP_064130448.1 | YceI family protein | - |
| A8Q77_RS03525 (SAMEA3174300_00698) | - | 788180..789082 (-) | 903 | WP_036494230.1 | LysR family transcriptional regulator | - |
| A8Q77_RS03530 (SAMEA3174300_00699) | trmB | 789352..790053 (+) | 702 | WP_064130449.1 | tRNA (guanosine(46)-N7)-methyltransferase TrmB | - |
| A8Q77_RS03535 (SAMEA3174300_00700) | - | 790161..790967 (-) | 807 | WP_064130450.1 | IS481 family transposase | - |
| A8Q77_RS03540 (SAMEA3174300_00701) | - | 791066..791479 (+) | 414 | WP_004284735.1 | DUF596 domain-containing protein | - |
| A8Q77_RS03545 (SAMEA3174300_00702) | - | 791625..792554 (+) | 930 | WP_004284733.1 | DUF637 domain-containing protein | - |
| A8Q77_RS03550 | - | 792551..792799 (+) | 249 | WP_156503407.1 | hypothetical protein | - |
| A8Q77_RS03555 (SAMEA3174300_00703) | - | 793085..793408 (+) | 324 | WP_040669974.1 | hypothetical protein | - |
| A8Q77_RS03565 (SAMEA3174300_00704) | serS | 793887..795182 (+) | 1296 | WP_064130452.1 | serine--tRNA ligase | - |
| A8Q77_RS03570 (SAMEA3174300_00705) | - | 795266..795892 (+) | 627 | WP_064130453.1 | LysE/ArgO family amino acid transporter | - |
| A8Q77_RS03575 (SAMEA3174300_00706) | - | 795976..796395 (-) | 420 | WP_004284722.1 | hypothetical protein | - |
| A8Q77_RS03580 (SAMEA3174300_00707) | holA | 796485..797489 (-) | 1005 | WP_004284721.1 | DNA polymerase III subunit delta | - |
| A8Q77_RS03585 (SAMEA3174300_00708) | lptE | 797489..797968 (-) | 480 | WP_064130454.1 | LPS assembly lipoprotein LptE | - |
| A8Q77_RS03590 (SAMEA3174300_00709) | gatB | 798043..799470 (-) | 1428 | WP_064130455.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB | - |
| A8Q77_RS10295 (SAMEA3174300_00710) | - | 799484..800110 (-) | 627 | WP_081463204.1 | MutH/Sau3AI family endonuclease | - |
| A8Q77_RS03600 (SAMEA3174300_00711) | - | 800100..800918 (-) | 819 | WP_004284717.1 | DNA-methyltransferase | - |
| A8Q77_RS03605 (SAMEA3174300_00712) | - | 800908..801726 (-) | 819 | WP_004284716.1 | DNA adenine methylase | - |
| A8Q77_RS03610 (SAMEA3174300_00713) | - | 801732..801938 (-) | 207 | WP_064130456.1 | hypothetical protein | - |
| A8Q77_RS03615 (SAMEA3174300_00714) | gatA | 802034..803488 (-) | 1455 | WP_004284711.1 | Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA | - |
Sequence
Protein
Download Length: 377 a.a. Molecular weight: 42152.19 Da Isoelectric Point: 6.4308
>NTDB_id=1143793 A8Q77_RS03325 WP_004285269.1 739135..740268(-) (pilU) [Neisseria weaveri strain NCTC13585]
MNHPNTSLPAKEELYSWLKHLNKYKGSDLFVTAKFPPAMKLDGKITPISDTPLDAERCMEMAFSIMTPKQIEEFTQTNEC
NFAISLPNTSRFRVNAMVQRGATALVFRSITSNIPSFDTLNLPPVLKDIAMQKRGLVIFVGGTGSGKSTSLASMIDFRNE
NSHDHIITIEDPIEFVHEHKNCIVTQREIGVDTENWHAALKNTLRQAPDVILIGEIRDRETMDYAIAFAETGHLCMATLH
ANSTNQALDRIINFFPEERRVQLLTDLSLNLQAFVSQRLIPREGGRGRVAAAEILMNSPLIAELILKGDVHGIKEVMKKS
TASGMQTFDQALYNLYETGQISFQDAIKNADSAHDLRTDIQLRSRRAQTAGPDLELI
MNHPNTSLPAKEELYSWLKHLNKYKGSDLFVTAKFPPAMKLDGKITPISDTPLDAERCMEMAFSIMTPKQIEEFTQTNEC
NFAISLPNTSRFRVNAMVQRGATALVFRSITSNIPSFDTLNLPPVLKDIAMQKRGLVIFVGGTGSGKSTSLASMIDFRNE
NSHDHIITIEDPIEFVHEHKNCIVTQREIGVDTENWHAALKNTLRQAPDVILIGEIRDRETMDYAIAFAETGHLCMATLH
ANSTNQALDRIINFFPEERRVQLLTDLSLNLQAFVSQRLIPREGGRGRVAAAEILMNSPLIAELILKGDVHGIKEVMKKS
TASGMQTFDQALYNLYETGQISFQDAIKNADSAHDLRTDIQLRSRRAQTAGPDLELI
Nucleotide
Download Length: 1134 bp
>NTDB_id=1143793 A8Q77_RS03325 WP_004285269.1 739135..740268(-) (pilU) [Neisseria weaveri strain NCTC13585]
ATGAACCATCCTAATACGTCTTTACCCGCAAAAGAAGAACTCTATTCTTGGCTGAAACACCTGAATAAATACAAAGGTTC
CGATTTATTCGTGACCGCCAAATTCCCGCCCGCCATGAAGCTGGACGGCAAAATCACCCCCATCAGCGATACGCCGCTGG
ACGCGGAACGCTGCATGGAAATGGCGTTTTCCATCATGACGCCCAAACAGATCGAAGAATTCACCCAAACCAACGAATGC
AACTTCGCCATCAGCCTGCCTAATACCAGCCGCTTCCGCGTCAATGCCATGGTGCAAAGAGGCGCAACCGCTTTGGTTTT
CCGCTCAATCACGTCCAACATTCCTTCGTTCGACACGCTCAACCTGCCGCCTGTATTAAAAGACATCGCCATGCAGAAAC
GCGGCTTGGTGATTTTTGTCGGCGGCACCGGCTCGGGCAAGTCCACGTCGCTGGCTTCCATGATCGACTTCCGCAATGAA
AACAGCCACGACCACATCATCACCATCGAAGACCCGATCGAATTTGTCCACGAACACAAAAACTGTATCGTTACCCAACG
CGAAATCGGCGTAGACACCGAAAACTGGCATGCCGCATTGAAAAACACCCTGCGTCAAGCACCCGATGTGATTCTGATCG
GCGAAATCCGCGACCGCGAAACCATGGACTATGCCATTGCCTTCGCCGAAACCGGCCACTTGTGTATGGCAACGCTGCAC
GCTAACAGCACCAACCAGGCTTTGGACCGCATTATCAACTTCTTCCCCGAAGAGCGCCGCGTCCAACTGCTCACCGACCT
GTCGCTCAACCTGCAAGCCTTCGTATCCCAACGCCTGATTCCGCGCGAAGGCGGCAGAGGCCGTGTTGCCGCAGCGGAAA
TCCTGATGAATTCTCCGCTCATTGCCGAACTGATTCTGAAAGGCGACGTACACGGGATTAAAGAAGTGATGAAAAAATCC
ACCGCATCCGGTATGCAGACATTCGACCAAGCCTTATACAACCTGTATGAAACCGGTCAAATCAGCTTCCAAGATGCCAT
CAAAAACGCCGACTCCGCACATGATTTGCGCACCGACATCCAATTGCGCAGCCGCCGCGCCCAAACCGCCGGCCCGGATT
TGGAATTGATTTAA
ATGAACCATCCTAATACGTCTTTACCCGCAAAAGAAGAACTCTATTCTTGGCTGAAACACCTGAATAAATACAAAGGTTC
CGATTTATTCGTGACCGCCAAATTCCCGCCCGCCATGAAGCTGGACGGCAAAATCACCCCCATCAGCGATACGCCGCTGG
ACGCGGAACGCTGCATGGAAATGGCGTTTTCCATCATGACGCCCAAACAGATCGAAGAATTCACCCAAACCAACGAATGC
AACTTCGCCATCAGCCTGCCTAATACCAGCCGCTTCCGCGTCAATGCCATGGTGCAAAGAGGCGCAACCGCTTTGGTTTT
CCGCTCAATCACGTCCAACATTCCTTCGTTCGACACGCTCAACCTGCCGCCTGTATTAAAAGACATCGCCATGCAGAAAC
GCGGCTTGGTGATTTTTGTCGGCGGCACCGGCTCGGGCAAGTCCACGTCGCTGGCTTCCATGATCGACTTCCGCAATGAA
AACAGCCACGACCACATCATCACCATCGAAGACCCGATCGAATTTGTCCACGAACACAAAAACTGTATCGTTACCCAACG
CGAAATCGGCGTAGACACCGAAAACTGGCATGCCGCATTGAAAAACACCCTGCGTCAAGCACCCGATGTGATTCTGATCG
GCGAAATCCGCGACCGCGAAACCATGGACTATGCCATTGCCTTCGCCGAAACCGGCCACTTGTGTATGGCAACGCTGCAC
GCTAACAGCACCAACCAGGCTTTGGACCGCATTATCAACTTCTTCCCCGAAGAGCGCCGCGTCCAACTGCTCACCGACCT
GTCGCTCAACCTGCAAGCCTTCGTATCCCAACGCCTGATTCCGCGCGAAGGCGGCAGAGGCCGTGTTGCCGCAGCGGAAA
TCCTGATGAATTCTCCGCTCATTGCCGAACTGATTCTGAAAGGCGACGTACACGGGATTAAAGAAGTGATGAAAAAATCC
ACCGCATCCGGTATGCAGACATTCGACCAAGCCTTATACAACCTGTATGAAACCGGTCAAATCAGCTTCCAAGATGCCAT
CAAAAACGCCGACTCCGCACATGATTTGCGCACCGACATCCAATTGCGCAGCCGCCGCGCCCAAACCGCCGGCCCGGATT
TGGAATTGATTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilU | Pseudomonas stutzeri DSM 10701 |
59.659 |
93.369 |
0.557 |
| pilU | Acinetobacter baylyi ADP1 |
57.349 |
92.042 |
0.528 |
| pilU | Vibrio cholerae strain A1552 |
50.975 |
95.225 |
0.485 |
| pilT | Deinococcus radiodurans R1 = ATCC 13939 = DSM 20539 |
43.827 |
85.942 |
0.377 |
| pilT | Legionella pneumophila strain Lp02 |
44.062 |
84.881 |
0.374 |
| pilT | Legionella pneumophila strain ERS1305867 |
44.062 |
84.881 |
0.374 |
| pilT | Acinetobacter baylyi ADP1 |
42.378 |
87.003 |
0.369 |
| pilT | Acinetobacter baumannii strain A118 |
42.593 |
85.942 |
0.366 |
| pilT | Acinetobacter nosocomialis M2 |
42.593 |
85.942 |
0.366 |
| pilT | Acinetobacter baumannii D1279779 |
42.593 |
85.942 |
0.366 |
| pilT | Neisseria meningitidis 8013 |
40.896 |
88.859 |
0.363 |
| pilT | Pseudomonas aeruginosa PAK |
41.768 |
87.003 |
0.363 |