Detailed information
Bioinformatically predicted
Overview
| Name | comX/comX2 | Type | Regulator |
| Locus tag | DQK99_RS00165 | Genome accession | NZ_LS483448 |
| Coordinates | 27926..28405 (+) | Length | 159 a.a. |
| NCBI ID | WP_000588911.1 | Uniprot ID | A0A2I5MSB2 |
| Organism | Streptococcus pneumoniae strain 4041STDY6836167 | ||
| Function | activate transcription of late competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 25846..100665 | 27926..28405 | within | 0 |
Gene organization within MGE regions
Location: 25846..100665
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DQK99_RS00160 | ftsH | 25846..27804 (+) | 1959 | WP_000744558.1 | ATP-dependent zinc metalloprotease FtsH | - |
| DQK99_RS00165 | comX/comX2 | 27926..28405 (+) | 480 | WP_000588911.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| DQK99_RS00185 | - | 31086..31295 (+) | 210 | Protein_34 | transposase | - |
| DQK99_RS00190 | - | 31330..32191 (-) | 862 | Protein_35 | transposase | - |
| DQK99_RS00195 | comW | 32457..32693 (+) | 237 | WP_000939545.1 | sigma(X)-activator ComW | Regulator |
| DQK99_RS00200 | - | 32924..34210 (+) | 1287 | WP_000205044.1 | adenylosuccinate synthase | - |
| DQK99_RS00205 | - | 34452..35600 (-) | 1149 | WP_000876726.1 | tyrosine-type recombinase/integrase | - |
| DQK99_RS00210 | - | 35774..36586 (-) | 813 | WP_001174228.1 | HIRAN domain-containing protein | - |
| DQK99_RS00215 | - | 36624..37007 (-) | 384 | WP_000136461.1 | ImmA/IrrE family metallo-endopeptidase | - |
| DQK99_RS00220 | - | 37020..37385 (-) | 366 | WP_050200267.1 | helix-turn-helix domain-containing protein | - |
| DQK99_RS11685 | - | 37671..37817 (+) | 147 | WP_172448391.1 | hypothetical protein | - |
| DQK99_RS00225 | - | 37810..38013 (+) | 204 | WP_050200268.1 | helix-turn-helix domain-containing protein | - |
| DQK99_RS12465 | - | 38025..38159 (+) | 135 | WP_257000724.1 | hypothetical protein | - |
| DQK99_RS00230 | - | 38156..38866 (+) | 711 | WP_069681343.1 | ORF6C domain-containing protein | - |
| DQK99_RS00235 | - | 38880..39137 (+) | 258 | WP_000370959.1 | hypothetical protein | - |
| DQK99_RS00240 | - | 39223..39543 (+) | 321 | WP_050279349.1 | hypothetical protein | - |
| DQK99_RS00245 | - | 39559..39849 (+) | 291 | WP_050254356.1 | hypothetical protein | - |
| DQK99_RS00250 | - | 39868..40692 (+) | 825 | WP_061742662.1 | phage replisome organizer N-terminal domain-containing protein | - |
| DQK99_RS00255 | - | 40707..41198 (+) | 492 | Protein_50 | ATP-binding protein | - |
| DQK99_RS12605 | - | 41213..41407 (+) | 195 | WP_000470303.1 | hypothetical protein | - |
| DQK99_RS00265 | - | 41407..41634 (+) | 228 | WP_000891969.1 | hypothetical protein | - |
| DQK99_RS00270 | - | 41761..41925 (+) | 165 | WP_000233201.1 | hypothetical protein | - |
| DQK99_RS00275 | - | 41915..42124 (+) | 210 | WP_001105098.1 | hypothetical protein | - |
| DQK99_RS00280 | - | 42096..42413 (+) | 318 | WP_000969662.1 | hypothetical protein | - |
| DQK99_RS00285 | - | 42415..42918 (+) | 504 | WP_050308165.1 | DUF1642 domain-containing protein | - |
| DQK99_RS00290 | - | 42918..43205 (+) | 288 | WP_111703758.1 | hypothetical protein | - |
| DQK99_RS00295 | - | 43205..43393 (+) | 189 | WP_001277861.1 | hypothetical protein | - |
| DQK99_RS00300 | - | 43661..44062 (+) | 402 | WP_000736391.1 | transcriptional activator | - |
| DQK99_RS00305 | - | 44251..44793 (+) | 543 | WP_000397552.1 | site-specific integrase | - |
| DQK99_RS00310 | - | 45104..45424 (+) | 321 | WP_000282427.1 | HNH endonuclease | - |
| DQK99_RS00315 | - | 45561..45953 (+) | 393 | WP_069288229.1 | P27 family phage terminase small subunit | - |
| DQK99_RS00320 | - | 45946..47676 (+) | 1731 | WP_000527305.1 | terminase large subunit | - |
| DQK99_RS00325 | - | 47684..47902 (+) | 219 | WP_001002923.1 | hypothetical protein | - |
| DQK99_RS00330 | - | 47920..49122 (+) | 1203 | WP_000510807.1 | phage portal protein | - |
| DQK99_RS00335 | - | 49106..49681 (+) | 576 | WP_001172113.1 | HK97 family phage prohead protease | - |
| DQK99_RS00340 | - | 49678..50850 (+) | 1173 | WP_001037662.1 | phage major capsid protein | - |
| DQK99_RS00345 | - | 50862..51152 (+) | 291 | WP_000120767.1 | hypothetical protein | - |
| DQK99_RS00350 | - | 51155..51436 (+) | 282 | WP_000371962.1 | phage head-tail connector protein | - |
| DQK99_RS00355 | - | 51423..51722 (+) | 300 | WP_000267061.1 | phage head closure protein | - |
| DQK99_RS00360 | - | 51719..52078 (+) | 360 | WP_000060159.1 | HK97 gp10 family phage protein | - |
| DQK99_RS00365 | - | 52075..52398 (+) | 324 | WP_000777003.1 | hypothetical protein | - |
| DQK99_RS00370 | - | 52410..52988 (+) | 579 | WP_000191277.1 | major tail protein | - |
| DQK99_RS00375 | - | 53000..53419 (+) | 420 | WP_024478843.1 | hypothetical protein | - |
| DQK99_RS00380 | - | 53697..56456 (+) | 2760 | WP_069288230.1 | phage tail tape measure protein | - |
| DQK99_RS00385 | - | 56453..57175 (+) | 723 | WP_061750696.1 | hypothetical protein | - |
| DQK99_RS00390 | - | 57176..64408 (+) | 7233 | WP_111703759.1 | phage tail spike protein | - |
| DQK99_RS12610 | - | 64405..64521 (+) | 117 | Protein_78 | dihydrodipicolinate reductase | - |
| DQK99_RS00400 | - | 64502..64705 (+) | 204 | WP_001091126.1 | hypothetical protein | - |
| DQK99_RS00405 | - | 64708..65058 (+) | 351 | WP_050198156.1 | hypothetical protein | - |
| DQK99_RS00410 | - | 65067..65483 (+) | 417 | WP_001165339.1 | phage holin family protein | - |
| DQK99_RS00415 | - | 65487..65819 (+) | 333 | WP_001186206.1 | phage holin | - |
| DQK99_RS00420 | lytA | 65823..66779 (+) | 957 | WP_111703760.1 | N-acetylmuramoyl-L-alanine amidase LytA | - |
| DQK99_RS00425 | - | 67049..67228 (-) | 180 | WP_001209433.1 | hypothetical protein | - |
| DQK99_RS11690 | - | 67370..67519 (-) | 150 | WP_001030863.1 | hypothetical protein | - |
| DQK99_RS00430 | tadA | 67800..68267 (+) | 468 | WP_000291870.1 | tRNA adenosine(34) deaminase TadA | - |
| DQK99_RS00440 | - | 68454..68897 (+) | 444 | WP_000701992.1 | dUTP diphosphatase | - |
| DQK99_RS00445 | - | 68899..69414 (+) | 516 | WP_000691236.1 | histidine phosphatase family protein | - |
| DQK99_RS00450 | radA | 69428..70789 (+) | 1362 | WP_078139281.1 | DNA repair protein RadA | Machinery gene |
| DQK99_RS00455 | - | 70862..71359 (+) | 498 | WP_172448392.1 | beta-class carbonic anhydrase | - |
| DQK99_RS00460 | - | 71384..72199 (+) | 816 | WP_000749763.1 | PrsW family intramembrane metalloprotease | - |
| DQK99_RS00465 | - | 72344..73312 (+) | 969 | WP_000010163.1 | ribose-phosphate diphosphokinase | - |
| DQK99_RS00470 | - | 73446..73727 (-) | 282 | Protein_93 | ISL3 family transposase | - |
| DQK99_RS12045 | - | 73854..74761 (-) | 908 | Protein_94 | Rpn family recombination-promoting nuclease/putative transposase | - |
| DQK99_RS00490 | polA | 75017..77650 (+) | 2634 | WP_001812977.1 | DNA polymerase I | - |
| DQK99_RS00495 | - | 77690..78946 (-) | 1257 | WP_111703762.1 | ISL3 family transposase | - |
| DQK99_RS00500 | - | 79045..80271 (-) | 1227 | WP_061816502.1 | ISL3 family transposase | - |
| DQK99_RS00505 | - | 80481..80918 (+) | 438 | WP_000076479.1 | CoA-binding protein | - |
| DQK99_RS12115 | - | 80959..81207 (+) | 249 | WP_001818074.1 | hypothetical protein | - |
| DQK99_RS00510 | - | 81236..82246 (-) | 1011 | WP_000009158.1 | YeiH family protein | - |
| DQK99_RS00515 | - | 82395..83564 (+) | 1170 | WP_000366345.1 | pyridoxal phosphate-dependent aminotransferase | - |
| DQK99_RS00520 | recO | 83561..84331 (+) | 771 | WP_000616167.1 | DNA repair protein RecO | - |
| DQK99_RS00525 | plsX | 84328..85320 (+) | 993 | WP_000717453.1 | phosphate acyltransferase PlsX | - |
| DQK99_RS00530 | - | 85326..85559 (+) | 234 | WP_000136447.1 | acyl carrier protein | - |
| DQK99_RS00535 | - | 85596..85895 (+) | 300 | Protein_105 | transposase family protein | - |
| DQK99_RS00540 | blpU | 86098..86328 (+) | 231 | WP_001093487.1 | bacteriocin-like peptide BlpU | - |
| DQK99_RS12470 | - | 86331..86456 (+) | 126 | WP_000346297.1 | PncF family bacteriocin immunity protein | - |
| DQK99_RS00545 | comA | 87045..89198 (+) | 2154 | WP_000668299.1 | peptide cleavage/export ABC transporter ComA | Regulator |
| DQK99_RS00550 | comB | 89211..90560 (+) | 1350 | WP_000801603.1 | competence pheromone export protein ComB | Regulator |
| DQK99_RS00555 | purC | 90730..91437 (+) | 708 | WP_000043304.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| DQK99_RS12615 | - | 91439..91582 (+) | 144 | WP_050167432.1 | hypothetical protein | - |
| DQK99_RS00565 | - | 91639..95364 (+) | 3726 | WP_000361163.1 | phosphoribosylformylglycinamidine synthase | - |
| DQK99_RS00570 | purF | 95457..96899 (+) | 1443 | WP_000220632.1 | amidophosphoribosyltransferase | - |
| DQK99_RS00575 | purM | 96936..97958 (+) | 1023 | WP_000182575.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| DQK99_RS00580 | purN | 97955..98500 (+) | 546 | WP_000717506.1 | phosphoribosylglycinamide formyltransferase | - |
| DQK99_RS00585 | - | 98584..99093 (+) | 510 | WP_000894018.1 | VanZ family protein | - |
| DQK99_RS00590 | purH | 99118..100665 (+) | 1548 | WP_000167085.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
Sequence
Protein
Download Length: 159 a.a. Molecular weight: 19873.52 Da Isoelectric Point: 7.3797
>NTDB_id=1141798 DQK99_RS00165 WP_000588911.1 27926..28405(+) (comX/comX2) [Streptococcus pneumoniae strain 4041STDY6836167]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGELSHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH
MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGELSHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH
Nucleotide
Download Length: 480 bp
>NTDB_id=1141798 DQK99_RS00165 WP_000588911.1 27926..28405(+) (comX/comX2) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGCTCAGTCATCGTATAAGTGAGGGAGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGACCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAAACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAGCAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGCTCAGTCATCGTATAAGTGAGGGAGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG
Domains
No domain identified.
Similar proteins
Only experimentally validated proteins are listed.