Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   DQK99_RS00195 Genome accession   NZ_LS483448
Coordinates   32457..32693 (+) Length   78 a.a.
NCBI ID   WP_000939545.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836167     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 27457..37693
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK99_RS00165 comX/comX2 27926..28405 (+) 480 WP_000588911.1 sigma-70 family RNA polymerase sigma factor Regulator
  DQK99_RS00185 - 31086..31295 (+) 210 Protein_34 transposase -
  DQK99_RS00190 - 31330..32191 (-) 862 Protein_35 transposase -
  DQK99_RS00195 comW 32457..32693 (+) 237 WP_000939545.1 sigma(X)-activator ComW Regulator
  DQK99_RS00200 - 32924..34210 (+) 1287 WP_000205044.1 adenylosuccinate synthase -
  DQK99_RS00205 - 34452..35600 (-) 1149 WP_000876726.1 tyrosine-type recombinase/integrase -
  DQK99_RS00210 - 35774..36586 (-) 813 WP_001174228.1 HIRAN domain-containing protein -
  DQK99_RS00215 - 36624..37007 (-) 384 WP_000136461.1 ImmA/IrrE family metallo-endopeptidase -
  DQK99_RS00220 - 37020..37385 (-) 366 WP_050200267.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9658.13 Da        Isoelectric Point: 6.7051

>NTDB_id=1141799 DQK99_RS00195 WP_000939545.1 32457..32693(+) (comW) [Streptococcus pneumoniae strain 4041STDY6836167]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=1141799 DQK99_RS00195 WP_000939545.1 32457..32693(+) (comW) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAAGGATTTTA
TTGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

100

100

1
  comW Streptococcus pneumoniae D39

100

100

1
  comW Streptococcus pneumoniae R6

100

100

1
  comW Streptococcus pneumoniae TIGR4

100

100

1
  comW Streptococcus mitis SK321

75.641

100

0.756
  comW Streptococcus mitis NCTC 12261

75.325

98.718

0.744

Multiple sequence alignment