Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQM73_RS11180 Genome accession   NZ_LS483346
Coordinates   2250548..2251489 (-) Length   313 a.a.
NCBI ID   WP_002927124.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11085     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2245548..2256489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS11145 (NCTC11085_02191) comYH 2246773..2247738 (-) 966 WP_002927105.1 class I SAM-dependent methyltransferase Machinery gene
  DQM73_RS11150 (NCTC11085_02192) comGG 2247820..2248212 (-) 393 WP_002927107.1 competence type IV pilus minor pilin ComGG -
  DQM73_RS11155 (NCTC11085_02193) comGF/cglF 2248193..2248630 (-) 438 WP_002927109.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM73_RS11160 (NCTC11085_02194) comGE/cglE 2248614..2248907 (-) 294 WP_002911065.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM73_RS11165 (NCTC11085_02195) comYD 2248873..2249307 (-) 435 WP_002934686.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM73_RS11170 (NCTC11085_02196) comYC 2249267..2249584 (-) 318 WP_002927120.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM73_RS11175 (NCTC11085_02197) comYB 2249584..2250618 (-) 1035 WP_260469178.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM73_RS11180 (NCTC11085_02198) comYA 2250548..2251489 (-) 942 WP_002927124.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM73_RS11185 (NCTC11085_02199) - 2251619..2251999 (-) 381 WP_002927126.1 DUF1033 family protein -
  DQM73_RS12370 (NCTC11085_02200) - 2252025..2252252 (-) 228 WP_002927128.1 hypothetical protein -
  DQM73_RS11195 (NCTC11085_02201) - 2252419..2253525 (-) 1107 WP_002927130.1 glycosyl hydrolase family 8 -
  DQM73_RS11200 (NCTC11085_02202) - 2253534..2254844 (-) 1311 WP_002901729.1 glycosyltransferase -
  DQM73_RS11205 (NCTC11085_02203) - 2254837..2254980 (-) 144 WP_002896778.1 hypothetical protein -
  DQM73_RS11210 (NCTC11085_02204) - 2254992..2255780 (-) 789 WP_002901732.1 hypothetical protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35955.20 Da        Isoelectric Point: 5.9428

>NTDB_id=1137727 DQM73_RS11180 WP_002927124.1 2250548..2251489(-) (comYA) [Streptococcus sanguinis strain NCTC11085]
MVQEIAKEMIRQARQEGAQDIYLIPKTTCYELYMRIGDERRFIKTYDFELLSAVISHFKFVAGMNVGEKRRSQLGSCDYD
CEEAKVSIRLSTVGDYRGFESLVIRLLHDEDRELRFWFEQLPELRKKIQARGLYLFSGPVGSGKTTLMYHLAQLKFSGQQ
VMSIEDPVEIKQEAMLQLQLNETIGMTYDSLIKLSLRHRPDLLIIGEIRDRETARAVVRASLTGATVFSTIHAKSVRGVY
ERLLELDVSEDELRMVLQGVCYQRLIGGGGVVDFVSQNYQEHEAAVWNQQIDQLFAEGHISAEQRQTEKIVYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1137727 DQM73_RS11180 WP_002927124.1 2250548..2251489(-) (comYA) [Streptococcus sanguinis strain NCTC11085]
ATGGTTCAAGAAATTGCAAAAGAAATGATTAGGCAGGCTCGGCAAGAGGGGGCGCAGGATATTTACCTCATTCCTAAGAC
TACTTGCTATGAGCTTTATATGAGAATCGGTGATGAACGTCGTTTTATAAAGACTTATGATTTCGAGCTTCTGTCAGCTG
TTATCAGCCACTTTAAGTTTGTCGCAGGTATGAATGTTGGAGAGAAGCGCCGCAGTCAGCTTGGGTCTTGCGATTATGAC
TGCGAGGAAGCCAAGGTTTCAATCCGGCTGTCGACAGTTGGGGATTACCGTGGTTTTGAAAGTCTGGTTATCCGACTCCT
TCATGACGAAGACAGGGAGCTGCGCTTTTGGTTTGAGCAATTGCCGGAGCTGCGCAAGAAAATTCAGGCTCGCGGCCTCT
ATCTATTCTCAGGACCAGTCGGCAGCGGCAAGACGACCTTGATGTATCATTTGGCTCAGCTCAAATTTTCTGGCCAGCAG
GTTATGTCAATTGAAGATCCGGTTGAAATTAAGCAAGAGGCTATGCTGCAGCTGCAGCTGAACGAAACCATTGGCATGAC
TTATGACAGTCTGATTAAGCTGTCTCTGCGACATCGGCCGGATCTCTTGATTATCGGGGAAATCCGTGATCGAGAGACAG
CTAGGGCAGTGGTTCGGGCAAGTTTGACCGGAGCTACGGTCTTTTCAACGATTCATGCCAAGAGTGTTCGCGGTGTCTAT
GAGCGGCTTTTGGAATTAGACGTTAGTGAGGACGAGCTAAGAATGGTGCTTCAAGGTGTTTGTTACCAGCGTTTAATTGG
GGGAGGAGGTGTCGTTGATTTTGTCAGTCAAAACTATCAAGAGCACGAAGCCGCAGTCTGGAATCAGCAGATTGATCAGC
TTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACAGAAAAAATTGTCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

80.323

99.042

0.796
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae D39

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae R6

74.76

100

0.748
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

74.76

100

0.748
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.441

100

0.744
  comYA Streptococcus mutans UA159

65.595

99.361

0.652
  comYA Streptococcus mutans UA140

65.595

99.361

0.652
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.516

99.042

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

40.647

88.818

0.361

Multiple sequence alignment