Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   DQM73_RS11145 Genome accession   NZ_LS483346
Coordinates   2246773..2247738 (-) Length   321 a.a.
NCBI ID   WP_002927105.1    Uniprot ID   A0A2X3VAF6
Organism   Streptococcus sanguinis strain NCTC11085     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2241773..2252738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS11125 (NCTC11085_02187) folP 2242755..2243708 (-) 954 WP_002927090.1 dihydropteroate synthase -
  DQM73_RS11130 (NCTC11085_02188) - 2243903..2244541 (-) 639 WP_002927094.1 hypothetical protein -
  DQM73_RS11135 (NCTC11085_02189) - 2244659..2245408 (-) 750 WP_002927096.1 CPBP family intramembrane glutamic endopeptidase -
  DQM73_RS11140 (NCTC11085_02190) - 2245543..2246736 (-) 1194 WP_002927099.1 acetate kinase -
  DQM73_RS11145 (NCTC11085_02191) comYH 2246773..2247738 (-) 966 WP_002927105.1 class I SAM-dependent methyltransferase Machinery gene
  DQM73_RS11150 (NCTC11085_02192) comGG 2247820..2248212 (-) 393 WP_002927107.1 competence type IV pilus minor pilin ComGG -
  DQM73_RS11155 (NCTC11085_02193) comGF/cglF 2248193..2248630 (-) 438 WP_002927109.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM73_RS11160 (NCTC11085_02194) comGE/cglE 2248614..2248907 (-) 294 WP_002911065.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM73_RS11165 (NCTC11085_02195) comYD 2248873..2249307 (-) 435 WP_002934686.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM73_RS11170 (NCTC11085_02196) comYC 2249267..2249584 (-) 318 WP_002927120.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM73_RS11175 (NCTC11085_02197) comYB 2249584..2250618 (-) 1035 WP_260469178.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM73_RS11180 (NCTC11085_02198) comYA 2250548..2251489 (-) 942 WP_002927124.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM73_RS11185 (NCTC11085_02199) - 2251619..2251999 (-) 381 WP_002927126.1 DUF1033 family protein -
  DQM73_RS12370 (NCTC11085_02200) - 2252025..2252252 (-) 228 WP_002927128.1 hypothetical protein -

Sequence

Protein


Download         Length: 321 a.a.        Molecular weight: 36629.60 Da        Isoelectric Point: 4.6183

>NTDB_id=1137721 DQM73_RS11145 WP_002927105.1 2246773..2247738(-) (comYH) [Streptococcus sanguinis strain NCTC11085]
MNFEKIEQAYTLILENVQNIQNALATNFYDALIEQNGIYLDGDTDLQEVLANDEKIRALHLTKEEWRRAYQFILMKAAQT
EPMQVNHQFTPDTIGFLITFLLDQLAHGEEADVLEIGSGTGNLAETVLNHTQKKIDYLGLELDDLLIDLSASIAEVMNSK
AHFAQGDAVRPQVLKESDIIISDLPVGYYPDDSIASRYEVASPDEHTYAHHLLMEQSLKYLKPGGYAIFLAPNDLLTSAQ
APLLKKWLLAKAQFIAMITLPESIFSSSKHAKTLFVLRKQEANNIQPFIYPLRDLQDHDEMFKFRQSFQNWYKDSEIQTK
F

Nucleotide


Download         Length: 966 bp        

>NTDB_id=1137721 DQM73_RS11145 WP_002927105.1 2246773..2247738(-) (comYH) [Streptococcus sanguinis strain NCTC11085]
ATGAATTTTGAAAAGATAGAACAAGCTTATACTCTGATTCTCGAAAACGTCCAGAATATCCAAAACGCTCTGGCGACCAA
TTTTTACGATGCTCTGATTGAGCAGAATGGCATTTACCTAGATGGAGATACTGATTTACAAGAGGTTCTGGCCAACGATG
AAAAAATCCGCGCTCTGCATTTGACCAAGGAAGAGTGGCGGAGAGCCTATCAGTTTATCCTGATGAAGGCGGCCCAGACG
GAGCCCATGCAGGTCAATCATCAATTCACACCTGACACAATTGGTTTTCTGATTACTTTCTTATTGGACCAGCTAGCTCA
CGGAGAGGAAGCTGATGTATTAGAAATCGGCAGTGGGACTGGAAATTTGGCGGAGACTGTTCTCAATCATACCCAAAAGA
AGATTGACTACTTAGGTCTGGAGCTAGATGATTTATTAATTGACCTTTCTGCCAGCATTGCAGAGGTTATGAACTCTAAG
GCTCACTTTGCTCAGGGGGATGCAGTTCGACCTCAGGTTCTGAAAGAGAGTGATATCATTATCAGTGATTTACCGGTTGG
TTATTATCCAGATGACAGTATCGCCTCCCGCTATGAAGTGGCTAGTCCGGATGAGCACACTTATGCCCATCATCTCCTGA
TGGAGCAATCACTCAAATATCTGAAGCCAGGTGGTTATGCTATATTTCTGGCGCCAAATGACCTCTTGACCAGCGCTCAA
GCTCCGTTGCTAAAAAAATGGCTCCTCGCCAAGGCTCAGTTTATCGCGATGATAACCTTGCCAGAGTCTATTTTCTCAAG
CAGCAAGCATGCCAAAACTCTTTTTGTCTTGAGGAAGCAAGAAGCGAATAACATTCAGCCCTTTATCTATCCTCTTCGGG
ATTTGCAGGATCATGATGAGATGTTTAAATTCCGTCAAAGTTTTCAAAACTGGTACAAAGATAGTGAAATTCAAACAAAA
TTTTGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-290)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2X3VAF6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

58.413

98.131

0.573
  comYH Streptococcus mutans UA140

58.095

98.131

0.57

Multiple sequence alignment