Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DQM73_RS11160 Genome accession   NZ_LS483346
Coordinates   2248614..2248907 (-) Length   97 a.a.
NCBI ID   WP_002911065.1    Uniprot ID   A0AA96NPW8
Organism   Streptococcus sanguinis strain NCTC11085     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2243614..2253907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS11130 (NCTC11085_02188) - 2243903..2244541 (-) 639 WP_002927094.1 hypothetical protein -
  DQM73_RS11135 (NCTC11085_02189) - 2244659..2245408 (-) 750 WP_002927096.1 CPBP family intramembrane glutamic endopeptidase -
  DQM73_RS11140 (NCTC11085_02190) - 2245543..2246736 (-) 1194 WP_002927099.1 acetate kinase -
  DQM73_RS11145 (NCTC11085_02191) comYH 2246773..2247738 (-) 966 WP_002927105.1 class I SAM-dependent methyltransferase Machinery gene
  DQM73_RS11150 (NCTC11085_02192) comGG 2247820..2248212 (-) 393 WP_002927107.1 competence type IV pilus minor pilin ComGG -
  DQM73_RS11155 (NCTC11085_02193) comGF/cglF 2248193..2248630 (-) 438 WP_002927109.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM73_RS11160 (NCTC11085_02194) comGE/cglE 2248614..2248907 (-) 294 WP_002911065.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM73_RS11165 (NCTC11085_02195) comYD 2248873..2249307 (-) 435 WP_002934686.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM73_RS11170 (NCTC11085_02196) comYC 2249267..2249584 (-) 318 WP_002927120.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM73_RS11175 (NCTC11085_02197) comYB 2249584..2250618 (-) 1035 WP_260469178.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM73_RS11180 (NCTC11085_02198) comYA 2250548..2251489 (-) 942 WP_002927124.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM73_RS11185 (NCTC11085_02199) - 2251619..2251999 (-) 381 WP_002927126.1 DUF1033 family protein -
  DQM73_RS12370 (NCTC11085_02200) - 2252025..2252252 (-) 228 WP_002927128.1 hypothetical protein -
  DQM73_RS11195 (NCTC11085_02201) - 2252419..2253525 (-) 1107 WP_002927130.1 glycosyl hydrolase family 8 -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10925.94 Da        Isoelectric Point: 10.6606

>NTDB_id=1137723 DQM73_RS11160 WP_002911065.1 2248614..2248907(-) (comGE/cglE) [Streptococcus sanguinis strain NCTC11085]
MASLKRRQLQASILLEALVAMAVFAAIASLLLGQISRSRKEQQILLQQEEVLRVARMALQTGQEELHINGIAVRQLKTDK
QLLVYHEGEVVIRVQKP

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1137723 DQM73_RS11160 WP_002911065.1 2248614..2248907(-) (comGE/cglE) [Streptococcus sanguinis strain NCTC11085]
ATGGCAAGTTTAAAAAGACGACAGCTTCAGGCTAGCATTCTGCTGGAAGCTCTGGTTGCCATGGCAGTTTTTGCGGCTAT
TGCTAGTCTGCTTCTGGGACAGATTAGCCGGTCTCGTAAAGAGCAGCAGATCCTTCTGCAGCAGGAAGAGGTGCTTCGGG
TAGCTCGTATGGCCCTGCAAACAGGACAAGAAGAGCTTCATATCAATGGAATTGCAGTGCGTCAGCTTAAGACAGATAAG
CAGCTGCTGGTCTATCACGAAGGGGAGGTAGTTATTCGTGTCCAAAAACCTTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae TIGR4

49.485

100

0.495
  comGE/cglE Streptococcus pneumoniae Rx1

49.485

100

0.495
  comGE/cglE Streptococcus pneumoniae D39

49.485

100

0.495
  comGE/cglE Streptococcus pneumoniae R6

49.485

100

0.495
  comGE/cglE Streptococcus mitis NCTC 12261

48.454

100

0.485
  comGE/cglE Streptococcus mitis SK321

48.454

100

0.485
  comYE Streptococcus mutans UA140

41.237

100

0.412
  comYE Streptococcus mutans UA159

41.237

100

0.412

Multiple sequence alignment