Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQM73_RS11175 Genome accession   NZ_LS483346
Coordinates   2249584..2250618 (-) Length   344 a.a.
NCBI ID   WP_260469178.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC11085     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2244584..2255618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM73_RS11135 (NCTC11085_02189) - 2244659..2245408 (-) 750 WP_002927096.1 CPBP family intramembrane glutamic endopeptidase -
  DQM73_RS11140 (NCTC11085_02190) - 2245543..2246736 (-) 1194 WP_002927099.1 acetate kinase -
  DQM73_RS11145 (NCTC11085_02191) comYH 2246773..2247738 (-) 966 WP_002927105.1 class I SAM-dependent methyltransferase Machinery gene
  DQM73_RS11150 (NCTC11085_02192) comGG 2247820..2248212 (-) 393 WP_002927107.1 competence type IV pilus minor pilin ComGG -
  DQM73_RS11155 (NCTC11085_02193) comGF/cglF 2248193..2248630 (-) 438 WP_002927109.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM73_RS11160 (NCTC11085_02194) comGE/cglE 2248614..2248907 (-) 294 WP_002911065.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQM73_RS11165 (NCTC11085_02195) comYD 2248873..2249307 (-) 435 WP_002934686.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM73_RS11170 (NCTC11085_02196) comYC 2249267..2249584 (-) 318 WP_002927120.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM73_RS11175 (NCTC11085_02197) comYB 2249584..2250618 (-) 1035 WP_260469178.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM73_RS11180 (NCTC11085_02198) comYA 2250548..2251489 (-) 942 WP_002927124.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM73_RS11185 (NCTC11085_02199) - 2251619..2251999 (-) 381 WP_002927126.1 DUF1033 family protein -
  DQM73_RS12370 (NCTC11085_02200) - 2252025..2252252 (-) 228 WP_002927128.1 hypothetical protein -
  DQM73_RS11195 (NCTC11085_02201) - 2252419..2253525 (-) 1107 WP_002927130.1 glycosyl hydrolase family 8 -
  DQM73_RS11200 (NCTC11085_02202) - 2253534..2254844 (-) 1311 WP_002901729.1 glycosyltransferase -
  DQM73_RS11205 (NCTC11085_02203) - 2254837..2254980 (-) 144 WP_002896778.1 hypothetical protein -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39055.93 Da        Isoelectric Point: 9.1581

>NTDB_id=1137726 DQM73_RS11175 WP_260469178.1 2249584..2250618(-) (comYB) [Streptococcus sanguinis strain NCTC11085]
MISFLQKDISVLSKGRQKKLSTPKQKKIIELFHNLFSSGFHLAEIVDFLRRSALLEEVYVAEMRAGLSAGQSFSEIVSRL
GFSDSVVTQLSLSELHGNLTLSLGKIEAYLENLSKVKKKLIEVGTYPLMLLGFLVLIMLGLRNYLLPQLDSQNLATQLIN
HLPQIFLWSSLAWAALVSVALFYYRKSSKIRFFSKLAALPFFGHLVQAYLTAYYAREWGNMIGQGLELSQIFAIMQEQPS
QLFKEIGEDMSAALQGGQGYADKVASYPFFKKELSLMIEYGEVKSKLGSELEVYAEKTWEEFFLRINRAMNFIQPLVFIF
VALVIVLLYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=1137726 DQM73_RS11175 WP_260469178.1 2249584..2250618(-) (comYB) [Streptococcus sanguinis strain NCTC11085]
TTGATCAGCTTTTTGCAGAAGGACATATCAGTGCTGAGCAAAGGCAGACAGAAAAAATTGTCTACGCCTAAGCAGAAAAA
GATTATTGAGCTCTTTCATAATCTCTTTAGCAGCGGTTTTCACTTAGCAGAGATTGTAGACTTTCTGAGACGAAGTGCCT
TGTTGGAGGAAGTGTATGTCGCAGAAATGCGGGCAGGCTTGTCAGCTGGTCAGTCCTTTTCAGAGATTGTCAGTCGACTG
GGATTTTCCGACAGCGTTGTAACCCAGCTTTCCTTATCTGAGCTGCATGGCAATCTGACACTTAGTCTGGGCAAAATTGA
GGCCTATCTGGAAAATCTGTCCAAGGTTAAGAAAAAATTGATAGAGGTAGGGACCTATCCTCTCATGCTGCTGGGCTTTT
TGGTCCTTATCATGCTGGGATTGCGCAACTATCTTCTGCCTCAATTAGACAGCCAGAATCTAGCTACTCAGCTGATTAAT
CACCTGCCTCAGATTTTTTTGTGGAGCAGCCTTGCTTGGGCCGCCTTGGTTTCAGTGGCTCTCTTTTATTATCGAAAGTC
ATCCAAGATTCGTTTTTTCAGCAAACTAGCAGCTCTGCCCTTTTTTGGACATTTGGTACAGGCTTACTTGACCGCTTATT
ATGCTCGTGAATGGGGAAATATGATTGGTCAGGGCTTGGAACTGAGTCAGATTTTTGCGATTATGCAGGAGCAGCCTTCC
CAGCTCTTTAAAGAAATCGGAGAAGACATGTCTGCAGCTTTGCAGGGCGGTCAAGGCTATGCGGACAAGGTGGCAAGCTA
TCCTTTCTTTAAGAAAGAATTGTCCTTAATGATCGAGTATGGTGAGGTAAAGTCCAAGTTGGGGAGTGAACTGGAAGTCT
ATGCTGAAAAGACTTGGGAGGAATTTTTCCTACGTATCAACCGAGCCATGAATTTCATTCAGCCCCTAGTATTTATTTTT
GTTGCCTTAGTGATTGTTTTACTTTATGCGGCAATGCTCTTGCCCATTTATCAGAATATGGAGGTTCATTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(29-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

73.837

100

0.738
  comGB/cglB Streptococcus mitis NCTC 12261

70.238

97.674

0.686
  comGB/cglB Streptococcus mitis SK321

69.048

97.674

0.674
  comGB/cglB Streptococcus pneumoniae TIGR4

68.155

97.674

0.666
  comGB/cglB Streptococcus pneumoniae R6

68.155

97.674

0.666
  comGB/cglB Streptococcus pneumoniae Rx1

68.155

97.674

0.666
  comGB/cglB Streptococcus pneumoniae D39

68.155

97.674

0.666
  comYB Streptococcus mutans UA140

61.224

99.709

0.61
  comYB Streptococcus mutans UA159

61.224

99.709

0.61
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.965

0.497

Multiple sequence alignment