Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   DQL23_RS03050 Genome accession   NZ_LS483341
Coordinates   644644..644961 (+) Length   105 a.a.
NCBI ID   WP_045634162.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7865     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 639644..649961
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS03035 (NCTC7865_00605) - 642270..642629 (+) 360 WP_008810065.1 DUF1033 family protein -
  DQL23_RS03040 (NCTC7865_00606) comYA 642742..643680 (+) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL23_RS03045 (NCTC7865_00607) comYB 643613..644647 (+) 1035 WP_060553795.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL23_RS03050 (NCTC7865_00608) comYC 644644..644961 (+) 318 WP_045634162.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL23_RS03055 (NCTC7865_00609) comYD 644921..645349 (+) 429 WP_060553796.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL23_RS03060 (NCTC7865_00610) comGE/cglE 645321..645614 (+) 294 WP_060553797.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL23_RS03065 (NCTC7865_00611) comGF/cglF 645598..646035 (+) 438 WP_060553798.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL23_RS03070 (NCTC7865_00612) comGG 646016..646447 (+) 432 WP_223358700.1 competence type IV pilus minor pilin ComGG -
  DQL23_RS03075 (NCTC7865_00613) comYH 646478..647431 (+) 954 WP_060553799.1 class I SAM-dependent methyltransferase Machinery gene
  DQL23_RS03080 (NCTC7865_00614) - 647481..648671 (+) 1191 WP_060553800.1 acetate kinase -
  DQL23_RS03085 (NCTC7865_00615) - 648720..649385 (+) 666 WP_060553801.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 105 a.a.        Molecular weight: 11447.31 Da        Isoelectric Point: 9.7153

>NTDB_id=1137464 DQL23_RS03050 WP_045634162.1 644644..644961(+) (comYC) [Streptococcus gordonii strain NCTC7865]
MNKLKNLRVKAFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVSDTGNAAVVKVVESQAELYELKNTGDQATLSKLVAAGN
ISQKQADSYKAYYGKNNSETQAVAN

Nucleotide


Download         Length: 318 bp        

>NTDB_id=1137464 DQL23_RS03050 WP_045634162.1 644644..644961(+) (comYC) [Streptococcus gordonii strain NCTC7865]
ATGAACAAATTAAAAAATTTACGTGTGAAAGCTTTTACTCTGGTAGAAATGCTAGTCGTCCTTCTGATCATCAGTGTCCT
TATGCTCTTGTTTGTACCTAATCTAACCAAGCAAAAAGAGGCTGTTTCGGATACTGGAAATGCTGCGGTGGTTAAGGTAG
TTGAAAGCCAGGCTGAGCTCTATGAACTCAAAAATACAGGAGATCAAGCAACCCTTAGCAAACTAGTCGCAGCTGGGAAC
ATTAGTCAAAAGCAAGCAGACTCTTACAAGGCTTATTATGGTAAGAACAATAGTGAGACTCAGGCAGTTGCAAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(8-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

99.048

100

0.99
  comYC Streptococcus mutans UA140

71.429

100

0.714
  comYC Streptococcus mutans UA159

71.429

100

0.714
  comGC/cglC Streptococcus mitis NCTC 12261

68.571

100

0.686
  comGC/cglC Streptococcus mitis SK321

67.961

98.095

0.667
  comGC/cglC Streptococcus pneumoniae Rx1

66.99

98.095

0.657
  comGC/cglC Streptococcus pneumoniae D39

66.99

98.095

0.657
  comGC/cglC Streptococcus pneumoniae TIGR4

66.99

98.095

0.657
  comGC/cglC Streptococcus pneumoniae R6

66.99

98.095

0.657
  comGC Lactococcus lactis subsp. cremoris KW2

59.794

92.381

0.552
  comYC Streptococcus suis isolate S10

61.798

84.762

0.524

Multiple sequence alignment