Detailed information NTG1137467

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: DQL23_RS03065
• Genome accession: NZ_LS483341
• Coordinates: 645598..646035 (+)
• Length: 145 a.a.
• NCBI ID: WP_060553798.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain NCTC7865
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 640598..651035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL23_RS03035 (NCTC7865_00605)	-	642270..642629 (+)	360	WP_008810065.1	DUF1033 family protein	-
DQL23_RS03040 (NCTC7865_00606)	comYA	642742..643680 (+)	939	WP_046164736.1	competence type IV pilus ATPase ComGA	Machinery gene
DQL23_RS03045 (NCTC7865_00607)	comYB	643613..644647 (+)	1035	WP_060553795.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQL23_RS03050 (NCTC7865_00608)	comYC	644644..644961 (+)	318	WP_045634162.1	competence type IV pilus major pilin ComGC	Machinery gene
DQL23_RS03055 (NCTC7865_00609)	comYD	644921..645349 (+)	429	WP_060553796.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQL23_RS03060 (NCTC7865_00610)	comGE/cglE	645321..645614 (+)	294	WP_060553797.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQL23_RS03065 (NCTC7865_00611)	comGF/cglF	645598..646035 (+)	438	WP_060553798.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQL23_RS03070 (NCTC7865_00612)	comGG	646016..646447 (+)	432	WP_223358700.1	competence type IV pilus minor pilin ComGG	-
DQL23_RS03075 (NCTC7865_00613)	comYH	646478..647431 (+)	954	WP_060553799.1	class I SAM-dependent methyltransferase	Machinery gene
DQL23_RS03080 (NCTC7865_00614)	-	647481..648671 (+)	1191	WP_060553800.1	acetate kinase	-
DQL23_RS03085 (NCTC7865_00615)	-	648720..649385 (+)	666	WP_060553801.1	CPBP family intramembrane glutamic endopeptidase	-
DQL23_RS03090 (NCTC7865_00616)	folP	649462..650427 (+)	966	WP_060553802.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16678.15 Da
• Isoelectric Point: 6.4939

>NTDB_id=1137467 DQL23_RS03065 WP_060553798.1 645598..646035(+) (comGF/cglF) [Streptococcus gordonii strain NCTC7865]
MLKKGKLAAFTLLEALVALLVISGGLLVFQAMTKLLASEIQYQEQTKAKEWLLFADQLDAELSRSHFEKVEQNRLYVKQD
DKSIAFGKSKSDDFRKTDGNGRGYQPMIYGLEAAQIHKEGQIVHLLLQFRDGLEREYIYRVEEEH

Nucleotide

• Length: 438 bp

>NTDB_id=1137467 DQL23_RS03065 WP_060553798.1 645598..646035(+) (comGF/cglF) [Streptococcus gordonii strain NCTC7865]
ATGTTGAAAAAAGGTAAACTAGCAGCCTTTACCCTGCTGGAAGCCTTAGTGGCCCTCTTGGTCATCAGTGGTGGCCTCTT
GGTTTTCCAGGCAATGACCAAGCTTCTAGCTAGTGAGATTCAGTATCAAGAGCAAACTAAGGCTAAGGAATGGCTCTTGT
TTGCGGACCAGTTAGATGCAGAATTATCTCGGAGCCATTTTGAAAAAGTCGAGCAAAATAGGCTTTATGTCAAACAAGAT
GACAAGTCGATTGCATTTGGTAAGTCTAAAAGCGATGATTTTAGAAAAACAGATGGGAATGGCCGTGGTTATCAGCCCAT
GATTTATGGACTAGAAGCTGCTCAAATACATAAAGAAGGTCAGATAGTTCATTTGCTTCTGCAGTTTAGAGATGGCCTAG
AAAGAGAGTACATCTATCGTGTTGAAGAAGAACATTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	67.376	97.241	0.655
comGF/cglF	Streptococcus pneumoniae Rx1	66.197	97.931	0.648
comGF/cglF	Streptococcus pneumoniae D39	66.197	97.931	0.648
comGF/cglF	Streptococcus pneumoniae R6	66.197	97.931	0.648
comGF/cglF	Streptococcus pneumoniae TIGR4	66.197	97.931	0.648
comGF/cglF	Streptococcus mitis SK321	65.248	97.241	0.634
comYF	Streptococcus mutans UA140	47.183	97.931	0.462
comYF	Streptococcus mutans UA159	46.479	97.931	0.455
comGF	Lactococcus lactis subsp. cremoris KW2	42.857	96.552	0.414