Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQL23_RS03045 Genome accession   NZ_LS483341
Coordinates   643613..644647 (+) Length   344 a.a.
NCBI ID   WP_060553795.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC7865     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 638613..649647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL23_RS03035 (NCTC7865_00605) - 642270..642629 (+) 360 WP_008810065.1 DUF1033 family protein -
  DQL23_RS03040 (NCTC7865_00606) comYA 642742..643680 (+) 939 WP_046164736.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL23_RS03045 (NCTC7865_00607) comYB 643613..644647 (+) 1035 WP_060553795.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL23_RS03050 (NCTC7865_00608) comYC 644644..644961 (+) 318 WP_045634162.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL23_RS03055 (NCTC7865_00609) comYD 644921..645349 (+) 429 WP_060553796.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL23_RS03060 (NCTC7865_00610) comGE/cglE 645321..645614 (+) 294 WP_060553797.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL23_RS03065 (NCTC7865_00611) comGF/cglF 645598..646035 (+) 438 WP_060553798.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL23_RS03070 (NCTC7865_00612) comGG 646016..646447 (+) 432 WP_223358700.1 competence type IV pilus minor pilin ComGG -
  DQL23_RS03075 (NCTC7865_00613) comYH 646478..647431 (+) 954 WP_060553799.1 class I SAM-dependent methyltransferase Machinery gene
  DQL23_RS03080 (NCTC7865_00614) - 647481..648671 (+) 1191 WP_060553800.1 acetate kinase -
  DQL23_RS03085 (NCTC7865_00615) - 648720..649385 (+) 666 WP_060553801.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 344 a.a.        Molecular weight: 39114.19 Da        Isoelectric Point: 9.1979

>NTDB_id=1137463 DQL23_RS03045 WP_060553795.1 643613..644647(+) (comYB) [Streptococcus gordonii strain NCTC7865]
MISFLQQDISILSKQRQKKLGTSKQKQVIELFNNLFSSGFHLAETVDFLGRSALLEQNYVQQMRRGLANGQAFSEIMTGL
GFSDAVVTQLSLAELHGNLSLALLKIEEYLDNLAKVKKKLIEVATYPMMLLGFLVLIMMGLRNYLLPQLSSQNFATQLIG
HLPTIFLLSVLMLLGLTGAIYLIFKGQKRIPVYSFLARLPFVGSFVKIYLTAYYAREWGNMIGQGLELSQIFQIMQEQRS
VLFQEIGQDLGQALQNGQEFSDKIASYPFFKKELSLIIEYGEVKSKLGSELEIYALKTWEEFFGRVNRTMNLIQPLVFVF
VALMIVLLYAAMLLPLYQNMEVHL

Nucleotide


Download         Length: 1035 bp        

>NTDB_id=1137463 DQL23_RS03045 WP_060553795.1 643613..644647(+) (comYB) [Streptococcus gordonii strain NCTC7865]
TTGATCAGCTTCTTGCAGCAGGACATATCCATCCTGAGCAAGCAGAGGCAGAAAAAATTAGGAACTAGCAAGCAAAAACA
GGTCATTGAACTGTTTAATAATTTATTCTCTAGTGGTTTTCATTTGGCTGAGACTGTGGATTTTTTAGGACGAAGTGCTC
TTTTGGAGCAGAACTATGTTCAGCAAATGCGTCGTGGCTTAGCTAATGGACAAGCATTTTCAGAGATTATGACTGGACTT
GGTTTTTCTGACGCGGTAGTAACCCAGCTGTCATTGGCTGAGCTACATGGGAATTTATCGCTTGCCTTGCTAAAAATAGA
GGAATATCTGGATAATCTTGCGAAGGTAAAAAAGAAGTTAATTGAAGTAGCGACCTATCCCATGATGCTTCTTGGCTTTT
TGGTATTGATTATGATGGGCTTGAGAAATTACCTATTACCCCAACTCAGCAGTCAAAATTTTGCAACTCAACTCATTGGT
CATTTGCCGACTATTTTTCTACTATCTGTCTTAATGTTACTTGGATTAACAGGAGCGATTTATCTGATTTTCAAAGGCCA
GAAACGGATCCCTGTATACTCTTTCTTAGCTCGCCTGCCTTTTGTTGGATCCTTTGTAAAGATTTACCTAACCGCCTATT
ATGCGCGTGAATGGGGCAATATGATTGGGCAAGGCTTGGAGCTCAGTCAGATTTTTCAGATTATGCAAGAGCAACGCTCG
GTTTTATTTCAGGAAATTGGTCAAGATTTAGGTCAAGCTTTACAAAACGGTCAAGAATTTTCAGATAAAATTGCTTCGTA
TCCTTTTTTCAAAAAGGAATTGTCTCTAATCATCGAATACGGGGAAGTCAAATCTAAGCTGGGAAGCGAACTAGAAATCT
ATGCTCTTAAGACTTGGGAAGAATTTTTTGGTAGGGTCAATCGGACCATGAATCTGATTCAGCCCCTAGTCTTTGTCTTT
GTAGCCTTGATGATTGTCTTATTGTATGCGGCAATGCTATTGCCCCTTTATCAAAATATGGAGGTTCATCTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(215-335)

Type II secretion system (T2SS), protein F (T2SSF)

(30-147)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

97.384

100

0.974
  comGB/cglB Streptococcus mitis NCTC 12261

71.848

99.128

0.712
  comGB/cglB Streptococcus mitis SK321

71.726

97.674

0.701
  comGB/cglB Streptococcus pneumoniae TIGR4

70.833

97.674

0.692
  comGB/cglB Streptococcus pneumoniae R6

70.833

97.674

0.692
  comGB/cglB Streptococcus pneumoniae Rx1

70.833

97.674

0.692
  comGB/cglB Streptococcus pneumoniae D39

70.833

97.674

0.692
  comYB Streptococcus mutans UA140

59.475

99.709

0.593
  comYB Streptococcus mutans UA159

59.184

99.709

0.59
  comGB Lactococcus lactis subsp. cremoris KW2

50.742

97.965

0.497

Multiple sequence alignment