Detailed information NTG1131066

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: H0514_RS00840
• Genome accession: NZ_LR822020
• Coordinates: 149102..149428 (+)
• Length: 108 a.a.
• NCBI ID: WP_179972346.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_956
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 144102..154428

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0514_RS00825 (STHERMO_0166)	-	146739..147101 (+)	363	WP_179972348.1	DUF1033 family protein	-
H0514_RS00830 (STHERMO_0167)	comGA/cglA/cilD	147182..148123 (+)	942	WP_179972347.1	competence type IV pilus ATPase ComGA	Machinery gene
H0514_RS00835 (STHERMO_0168)	comYB	148005..149105 (+)	1101	WP_179973355.1	competence type IV pilus assembly protein ComGB	Machinery gene
H0514_RS00840 (STHERMO_0169)	comYC	149102..149428 (+)	327	WP_179972346.1	competence type IV pilus major pilin ComGC	Machinery gene
H0514_RS00845 (STHERMO_0170)	comGD	149388..149816 (+)	429	WP_269473123.1	competence type IV pilus minor pilin ComGD	-
H0514_RS00850 (STHERMO_0171)	comGE	149788..150081 (+)	294	WP_179972344.1	competence type IV pilus minor pilin ComGE	-
H0514_RS00855 (STHERMO_0172)	comYF	150065..150502 (+)	438	WP_179972343.1	competence type IV pilus minor pilin ComGF	Machinery gene
H0514_RS00860 (STHERMO_0173)	comGG	150480..150791 (+)	312	WP_179972342.1	competence type IV pilus minor pilin ComGG	-
H0514_RS00865 (STHERMO_0174)	comYH	150842..151798 (+)	957	WP_179972341.1	class I SAM-dependent methyltransferase	Machinery gene
H0514_RS00870 (STHERMO_0175)	-	151854..153047 (+)	1194	WP_179972340.1	acetate kinase	-
H0514_RS00875 (STHERMO_0176)	-	153295..153492 (+)	198	WP_179972339.1	helix-turn-helix transcriptional regulator	-
H0514_RS11190 (STHERMO_0177)	-	153504..153945 (+)	442	Protein_129	CAAX protease	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 11944.02 Da
• Isoelectric Point: 9.9219

>NTDB_id=1131066 H0514_RS00840 WP_179972346.1 149102..149428(+) (comYC) [Streptococcus thermophilus isolate STH_CIRM_956]
MKLMLKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAELYEMKNNKTASLAALVS
EGQITQKQADSYNDYYAKHGSESRSVAN

Nucleotide

• Length: 327 bp

>NTDB_id=1131066 H0514_RS00840 WP_179972346.1 149102..149428(+) (comYC) [Streptococcus thermophilus isolate STH_CIRM_956]
ATGAAATTGATGTTAAAAAAATTGAATGCCGTTAAATTACGAGCCTTTACTCTGATTGAAATGCTAGTCGTACTTCTCAT
TATCAGTATTCTCCTTTTGCTCTTTGTTCCTAACTTAAGCAAGCAGAAGGATTCCGTTAAGGAAACTGGAAATGCGGCTG
TAGTCAAGGTCGTGGATTCTCAGGCAGAACTTTATGAAATGAAGAATAACAAGACAGCTAGCTTGGCAGCTCTTGTTTCA
GAAGGTCAAATTACGCAAAAACAGGCAGATTCATACAATGATTACTATGCGAAACATGGTAGTGAAAGCCGCTCAGTGGC
CAATTAG

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (14-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus mutans UA140	70.192	96.296	0.676
comYC	Streptococcus mutans UA159	70.192	96.296	0.676
comYC	Streptococcus gordonii str. Challis substr. CH1	64.762	97.222	0.63
comGC/cglC	Streptococcus mitis SK321	61.321	98.148	0.602
comGC/cglC	Streptococcus mitis NCTC 12261	58.333	100	0.583
comGC/cglC	Streptococcus pneumoniae D39	57.547	98.148	0.565
comGC/cglC	Streptococcus pneumoniae R6	57.547	98.148	0.565
comGC/cglC	Streptococcus pneumoniae Rx1	57.547	98.148	0.565
comGC/cglC	Streptococcus pneumoniae TIGR4	57.547	98.148	0.565
comGC	Lactococcus lactis subsp. cremoris KW2	56.604	98.148	0.556
comYC	Streptococcus suis isolate S10	60.227	81.481	0.491
comGC	Staphylococcus aureus MW2	50	72.222	0.361
comGC	Staphylococcus aureus N315	50	72.222	0.361