Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX   Type   Regulator
Locus tag   H0504_RS08200 Genome accession   NZ_LR822011
Coordinates   1598226..1598723 (-) Length   165 a.a.
NCBI ID   WP_002949220.1    Uniprot ID   A0A0M4HKA9
Organism   Streptococcus thermophilus isolate STH_CIRM_23     
Function   activation of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1599477..1603752 1598226..1598723 flank 754


Gene organization within MGE regions


Location: 1598226..1603752
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0504_RS08200 (STHERMO_1839) comX 1598226..1598723 (-) 498 WP_002949220.1 sigma factor Regulator
  H0504_RS08205 - 1599015..1599119 (-) 105 Protein_1582 IS200/IS605 family transposase -
  H0504_RS09370 (STHERMO_1840) - 1599477..1599941 (+) 465 Protein_1583 transposase family protein -
  H0504_RS08215 (STHERMO_1842) - 1600202..1601392 (-) 1191 WP_002949216.1 SAM-dependent methyltransferase -
  H0504_RS08220 (STHERMO_1843) - 1601495..1601821 (-) 327 WP_014607875.1 M20/M25/M40 family metallo-hydrolase -
  H0504_RS08225 - 1602010..1602332 (+) 323 Protein_1586 transposase -
  H0504_RS08230 (STHERMO_1845) - 1602417..1602638 (-) 222 WP_002948904.1 DUF4649 family protein -
  H0504_RS08235 (STHERMO_1846) - 1602931..1603745 (+) 815 Protein_1588 ISL3 family transposase -

Sequence

Protein


Download         Length: 165 a.a.        Molecular weight: 20160.12 Da        Isoelectric Point: 5.2073

>NTDB_id=1130691 H0504_RS08200 WP_002949220.1 1598226..1598723(-) (comX) [Streptococcus thermophilus isolate STH_CIRM_23]
MEQEVFVKAYEKVRPIVLKAFRQYFIQLWDQADMEQEAMMTLYQLLKKFPDLEKDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYVEISDIAFCIPNKELDMVDRLAYDEQLNAFREQLSSEDSLKLDRLLGGECFRGRKKMIRELRFWMVDFDP
CNEED

Nucleotide


Download         Length: 498 bp        

>NTDB_id=1130691 H0504_RS08200 WP_002949220.1 1598226..1598723(-) (comX) [Streptococcus thermophilus isolate STH_CIRM_23]
ATGGAACAAGAAGTTTTTGTTAAGGCATATGAAAAGGTAAGGCCAATTGTACTTAAGGCTTTTAGGCAATACTTTATTCA
GCTTTGGGATCAAGCTGACATGGAGCAAGAGGCGATGATGACTTTGTATCAGCTTTTAAAAAAGTTTCCTGATTTAGAGA
AAGATGATGATAAGTTACGTCGTTACTTTAAAACTAAGTTTAGGAATCGACTTAATGATGAAGTGAGGCGGCAGGAGTCA
GTAAAACGTCAAGCTAATAGACAGTGCTATGTTGAAATTTCAGATATTGCCTTTTGTATTCCCAATAAGGAGCTAGATAT
GGTTGATAGACTTGCTTATGATGAACAGCTTAATGCATTTCGTGAGCAGTTATCATCGGAAGATTCTCTTAAGTTGGATC
GATTGTTGGGTGGTGAATGCTTTAGGGGAAGGAAAAAGATGATACGAGAGTTAAGATTTTGGATGGTTGACTTTGATCCA
TGTAATGAAGAAGACTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(10-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M4HKA9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.