Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX   Type   Regulator
Locus tag   H0503_RS00805 Genome accession   NZ_LR822009
Coordinates   143764..144261 (+) Length   165 a.a.
NCBI ID   WP_002949220.1    Uniprot ID   A0A0M4HKA9
Organism   Streptococcus thermophilus isolate STH_CIRM_19     
Function   activation of late competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 134713..143010 143764..144261 flank 754


Gene organization within MGE regions


Location: 134713..144261
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0503_RS00760 (STHERMO_0136) - 134713..135969 (-) 1257 WP_179967061.1 ISL3-like element ISSth1 family transposase -
  H0503_RS09635 - 136225..136479 (-) 255 Protein_111 ISL3 family transposase -
  H0503_RS00765 (STHERMO_0138) amiA 136752..138719 (+) 1968 WP_014607872.1 peptide ABC transporter substrate-binding protein Regulator
  H0503_RS00770 (STHERMO_0139) - 138764..139578 (-) 815 Protein_113 ISL3 family transposase -
  H0503_RS00775 (STHERMO_0140) - 139871..140092 (+) 222 WP_002948904.1 DUF4649 family protein -
  H0503_RS00780 - 140177..140499 (-) 323 Protein_115 transposase -
  H0503_RS00785 (STHERMO_0142) - 140688..141014 (+) 327 WP_014607875.1 M20/M25/M40 family metallo-hydrolase -
  H0503_RS00790 (STHERMO_0143) - 141096..142286 (+) 1191 WP_179971453.1 SAM-dependent methyltransferase -
  H0503_RS00795 (STHERMO_0144) - 142546..143010 (-) 465 Protein_118 transposase family protein -
  H0503_RS00800 - 143368..143472 (+) 105 Protein_119 IS200/IS605 family transposase -
  H0503_RS00805 (STHERMO_0145) comX 143764..144261 (+) 498 WP_002949220.1 sigma factor Regulator

Sequence

Protein


Download         Length: 165 a.a.        Molecular weight: 20160.12 Da        Isoelectric Point: 5.2073

>NTDB_id=1130534 H0503_RS00805 WP_002949220.1 143764..144261(+) (comX) [Streptococcus thermophilus isolate STH_CIRM_19]
MEQEVFVKAYEKVRPIVLKAFRQYFIQLWDQADMEQEAMMTLYQLLKKFPDLEKDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYVEISDIAFCIPNKELDMVDRLAYDEQLNAFREQLSSEDSLKLDRLLGGECFRGRKKMIRELRFWMVDFDP
CNEED

Nucleotide


Download         Length: 498 bp        

>NTDB_id=1130534 H0503_RS00805 WP_002949220.1 143764..144261(+) (comX) [Streptococcus thermophilus isolate STH_CIRM_19]
ATGGAACAAGAAGTTTTTGTTAAGGCATATGAAAAGGTAAGGCCAATTGTACTTAAGGCGTTTAGGCAATACTTTATTCA
GCTTTGGGATCAAGCTGACATGGAGCAAGAGGCGATGATGACTTTGTATCAGCTTTTAAAAAAGTTTCCTGATTTAGAGA
AAGATGATGATAAGTTACGTCGTTACTTTAAAACTAAGTTTAGGAATCGACTTAATGATGAAGTGAGGCGGCAGGAGTCA
GTAAAACGTCAAGCTAATAGACAGTGTTATGTTGAAATTTCAGATATTGCCTTTTGTATTCCCAATAAGGAGCTAGATAT
GGTTGATAGACTTGCTTATGATGAACAGCTTAATGCTTTTCGTGAGCAGTTATCATCGGAAGATTCTCTTAAGTTGGATC
GATTGTTGGGTGGTGAATGCTTTAGGGGAAGGAAAAAGATGATACGAGAGTTAAGATTTTGGATGGTTGACTTTGATCCA
TGTAATGAAGAAGACTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(10-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M4HKA9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.