Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   FGL12_RS09810 Genome accession   NZ_LR594041
Coordinates   2029399..2029716 (-) Length   105 a.a.
NCBI ID   WP_012130940.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC9124     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2024399..2034716
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS11060 - 2024975..2025406 (-) 432 WP_231069241.1 CPBP family intramembrane glutamic endopeptidase -
  FGL12_RS09780 (NCTC9124_01971) - 2025688..2026878 (-) 1191 WP_012130934.1 acetate kinase -
  FGL12_RS09785 (NCTC9124_01972) comYH 2026928..2027881 (-) 954 WP_012130935.1 class I SAM-dependent methyltransferase Machinery gene
  FGL12_RS09790 (NCTC9124_01973) comGG 2027912..2028343 (-) 432 WP_223341947.1 competence type IV pilus minor pilin ComGG -
  FGL12_RS09795 (NCTC9124_01974) comGF/cglF 2028324..2028713 (-) 390 WP_241974402.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL12_RS09800 (NCTC9124_01975) comGE/cglE 2028740..2029039 (-) 300 WP_138101351.1 competence type IV pilus minor pilin ComGE Machinery gene
  FGL12_RS09805 (NCTC9124_01976) comYD 2029011..2029439 (-) 429 WP_012130939.1 competence type IV pilus minor pilin ComGD Machinery gene
  FGL12_RS09810 (NCTC9124_01977) comYC 2029399..2029716 (-) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL12_RS09815 (NCTC9124_01978) comYB 2029713..2030747 (-) 1035 WP_012130941.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL12_RS09820 (NCTC9124_01979) comYA 2030659..2031618 (-) 960 WP_012130942.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL12_RS09825 (NCTC9124_01980) - 2031720..2032088 (-) 369 WP_012130943.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 105 a.a.        Molecular weight: 11461.38 Da        Isoelectric Point: 9.9223

>NTDB_id=1127525 FGL12_RS09810 WP_012130940.1 2029399..2029716(-) (comYC) [Streptococcus gordonii strain NCTC9124]
MNKLKKLRVKAFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVSDTGNAAVVKVVESQAELYELKNTGDQATLSKLVAAGN
ISQKQADSYKAYYGKNNSETQAVAN

Nucleotide


Download         Length: 318 bp        

>NTDB_id=1127525 FGL12_RS09810 WP_012130940.1 2029399..2029716(-) (comYC) [Streptococcus gordonii strain NCTC9124]
ATGAACAAATTAAAAAAATTACGTGTGAAAGCTTTTACTTTAGTGGAAATGCTAGTTGTCCTTCTGATCATCAGTGTCCT
TATGCTCTTATTTGTCCCTAATTTAACCAAGCAAAAAGAGGCAGTTTCGGATACTGGAAATGCTGCGGTGGTTAAGGTAG
TTGAGAGCCAGGCTGAGCTCTATGAACTCAAAAATACAGGAGATCAAGCAACCCTCAGCAAATTAGTCGCAGCTGGGAAC
ATTAGTCAAAAGCAAGCAGACTCTTACAAGGCTTATTATGGTAAGAACAATAGTGAGACTCAGGCAGTTGCCAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(8-30)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

100

100

1
  comYC Streptococcus mutans UA140

71.429

100

0.714
  comYC Streptococcus mutans UA159

71.429

100

0.714
  comGC/cglC Streptococcus mitis NCTC 12261

69.524

100

0.695
  comGC/cglC Streptococcus mitis SK321

68.932

98.095

0.676
  comGC/cglC Streptococcus pneumoniae Rx1

67.961

98.095

0.667
  comGC/cglC Streptococcus pneumoniae D39

67.961

98.095

0.667
  comGC/cglC Streptococcus pneumoniae TIGR4

67.961

98.095

0.667
  comGC/cglC Streptococcus pneumoniae R6

67.961

98.095

0.667
  comGC Lactococcus lactis subsp. cremoris KW2

59.794

92.381

0.552
  comYC Streptococcus suis isolate S10

61.798

84.762

0.524

Multiple sequence alignment