Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   FGL12_RS09785 Genome accession   NZ_LR594041
Coordinates   2026928..2027881 (-) Length   317 a.a.
NCBI ID   WP_012130935.1    Uniprot ID   A8AZH3
Organism   Streptococcus gordonii strain NCTC9124     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2021928..2032881
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS09765 (NCTC9124_01968) - 2022596..2023927 (-) 1332 WP_041789910.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  FGL12_RS09770 (NCTC9124_01969) folP 2023932..2024897 (-) 966 WP_012130932.1 dihydropteroate synthase -
  FGL12_RS11060 - 2024975..2025406 (-) 432 WP_231069241.1 CPBP family intramembrane glutamic endopeptidase -
  FGL12_RS09780 (NCTC9124_01971) - 2025688..2026878 (-) 1191 WP_012130934.1 acetate kinase -
  FGL12_RS09785 (NCTC9124_01972) comYH 2026928..2027881 (-) 954 WP_012130935.1 class I SAM-dependent methyltransferase Machinery gene
  FGL12_RS09790 (NCTC9124_01973) comGG 2027912..2028343 (-) 432 WP_223341947.1 competence type IV pilus minor pilin ComGG -
  FGL12_RS09795 (NCTC9124_01974) comGF/cglF 2028324..2028713 (-) 390 WP_241974402.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL12_RS09800 (NCTC9124_01975) comGE/cglE 2028740..2029039 (-) 300 WP_138101351.1 competence type IV pilus minor pilin ComGE Machinery gene
  FGL12_RS09805 (NCTC9124_01976) comYD 2029011..2029439 (-) 429 WP_012130939.1 competence type IV pilus minor pilin ComGD Machinery gene
  FGL12_RS09810 (NCTC9124_01977) comYC 2029399..2029716 (-) 318 WP_012130940.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL12_RS09815 (NCTC9124_01978) comYB 2029713..2030747 (-) 1035 WP_012130941.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL12_RS09820 (NCTC9124_01979) comYA 2030659..2031618 (-) 960 WP_012130942.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL12_RS09825 (NCTC9124_01980) - 2031720..2032088 (-) 369 WP_012130943.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36000.10 Da        Isoelectric Point: 4.8695

>NTDB_id=1127521 FGL12_RS09785 WP_012130935.1 2026928..2027881(-) (comYH) [Streptococcus gordonii strain NCTC9124]
MNFEKIEEAYTLLLENVQVIQNKLSTNFYDALIEQNGIYLDGQTDLEIVKKNHQTLKSLKLSREEWRRAYQFILMKAAQT
EPLQANHQFTPDAIGFLLIFIIDQLMVASDITLLEMGSGTGNLAETILNNSQKEIDYLGLEIDDLLIDLSASIAEVMGSK
AHFAQGDAVRPQVLKESDLIISDLPVGYYPDDQIASRYQVASQTEHTYAHHLLMEQALKYLKADGYAIFLAPNHLLTSPQ
SDLLKSWLKDNASLVAMIALPEKLFASVSQAKTVFVLQKQKNIKTEPFAYALTDLQNHDEITRFRESFQKWRKVSEN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=1127521 FGL12_RS09785 WP_012130935.1 2026928..2027881(-) (comYH) [Streptococcus gordonii strain NCTC9124]
ATGAATTTTGAAAAAATCGAAGAAGCCTATACGCTCCTTTTAGAAAATGTCCAAGTCATTCAAAACAAGCTTTCAACTAA
TTTTTATGATGCCTTAATCGAGCAAAACGGTATCTATTTGGATGGACAAACGGACTTAGAAATCGTTAAAAAGAATCATC
AGACCTTGAAGAGCTTAAAGCTAAGCAGAGAAGAATGGCGCAGAGCCTATCAGTTCATTCTGATGAAGGCTGCTCAGACA
GAGCCTTTGCAAGCCAATCATCAGTTTACACCAGATGCCATTGGTTTTCTGCTGATTTTCATCATCGACCAGCTGATGGT
AGCATCAGATATTACTCTTCTTGAGATGGGGAGCGGAACCGGAAATCTTGCAGAGACAATCCTGAACAATAGTCAGAAAG
AGATTGATTATCTAGGATTAGAGATTGATGATTTACTGATTGACCTATCTGCCAGTATTGCAGAAGTGATGGGTTCAAAG
GCACATTTTGCCCAGGGAGATGCTGTGCGCCCTCAAGTTCTAAAAGAGAGCGACTTGATTATTAGTGATCTGCCTGTCGG
TTACTATCCGGATGATCAGATTGCCAGTCGCTACCAGGTAGCCAGTCAGACGGAGCACACCTATGCTCATCATCTATTGA
TGGAGCAGGCTTTAAAGTATTTGAAGGCCGATGGCTATGCAATCTTCTTAGCTCCTAATCACCTCTTAACCAGCCCGCAG
AGCGACTTACTTAAATCCTGGCTCAAAGACAATGCCAGCTTGGTTGCGATGATTGCTTTGCCAGAAAAACTCTTTGCATC
AGTTTCTCAGGCTAAGACGGTTTTTGTTTTGCAAAAACAAAAAAATATAAAAACGGAACCTTTTGCCTATGCATTGACAG
ATCTACAAAATCATGATGAAATTACTCGCTTTCGCGAAAGTTTTCAAAAATGGCGCAAAGTTAGTGAAAACTGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AZH3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

58.786

98.738

0.58
  comYH Streptococcus mutans UA140

58.786

98.738

0.58

Multiple sequence alignment