Detailed information NTG1127522

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: FGL12_RS09795
• Genome accession: NZ_LR594041
• Coordinates: 2028324..2028713 (-)
• Length: 129 a.a.
• NCBI ID: WP_241974402.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain NCTC9124
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2023324..2033713

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL12_RS09770 (NCTC9124_01969)	folP	2023932..2024897 (-)	966	WP_012130932.1	dihydropteroate synthase	-
FGL12_RS11060	-	2024975..2025406 (-)	432	WP_231069241.1	CPBP family intramembrane glutamic endopeptidase	-
FGL12_RS09780 (NCTC9124_01971)	-	2025688..2026878 (-)	1191	WP_012130934.1	acetate kinase	-
FGL12_RS09785 (NCTC9124_01972)	comYH	2026928..2027881 (-)	954	WP_012130935.1	class I SAM-dependent methyltransferase	Machinery gene
FGL12_RS09790 (NCTC9124_01973)	comGG	2027912..2028343 (-)	432	WP_223341947.1	competence type IV pilus minor pilin ComGG	-
FGL12_RS09795 (NCTC9124_01974)	comGF/cglF	2028324..2028713 (-)	390	WP_241974402.1	competence type IV pilus minor pilin ComGF	Machinery gene
FGL12_RS09800 (NCTC9124_01975)	comGE/cglE	2028740..2029039 (-)	300	WP_138101351.1	competence type IV pilus minor pilin ComGE	Machinery gene
FGL12_RS09805 (NCTC9124_01976)	comYD	2029011..2029439 (-)	429	WP_012130939.1	competence type IV pilus minor pilin ComGD	Machinery gene
FGL12_RS09810 (NCTC9124_01977)	comYC	2029399..2029716 (-)	318	WP_012130940.1	competence type IV pilus major pilin ComGC	Machinery gene
FGL12_RS09815 (NCTC9124_01978)	comYB	2029713..2030747 (-)	1035	WP_012130941.1	competence type IV pilus assembly protein ComGB	Machinery gene
FGL12_RS09820 (NCTC9124_01979)	comYA	2030659..2031618 (-)	960	WP_012130942.1	competence type IV pilus ATPase ComGA	Machinery gene
FGL12_RS09825 (NCTC9124_01980)	-	2031720..2032088 (-)	369	WP_012130943.1	DUF1033 family protein	-

Sequence

Protein

• Length: 129 a.a.
• Molecular weight: 14908.99 Da
• Isoelectric Point: 6.0990

>NTDB_id=1127522 FGL12_RS09795 WP_241974402.1 2028324..2028713(-) (comGF/cglF) [Streptococcus gordonii strain NCTC9124]
MALLVISGGLLVFQAMTKLLASEIQYQEQTKAKEWLLFADQLDAELSRSHFEKVEQNKLYVKQDGKSIAFGKSKSDDFRK
TDANGRGYQPMIYGLEAAQIHKEGQIVHLLLQFRDGLEREYIYRVEEEH

Nucleotide

• Length: 390 bp

>NTDB_id=1127522 FGL12_RS09795 WP_241974402.1 2028324..2028713(-) (comGF/cglF) [Streptococcus gordonii strain NCTC9124]
GTGGCCCTCTTGGTCATCAGTGGTGGCCTCTTGGTTTTCCAGGCCATGACCAAGCTTCTAGCCAGCGAGATTCAGTATCA
AGAGCAAACTAAGGCCAAGGAATGGCTTTTGTTTGCGGACCAGTTAGATGCAGAATTATCTCGGAGCCATTTTGAAAAAG
TCGAGCAAAATAAGCTTTATGTCAAACAAGATGGCAAGTCGATTGCATTTGGTAAGTCTAAAAGCGATGATTTTAGAAAA
ACAGATGCGAATGGCCGTGGTTATCAGCCCATGATTTATGGACTAGAAGCAGCTCAAATACATAAAGAAGGTCAGATAGT
TCATTTGCTTCTGCAGTTTAGAGATGGCCTAGAAAGAGAGTACATCTATCGTGTTGAAGAAGAACATTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (22-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	68.504	98.45	0.674
comGF/cglF	Streptococcus pneumoniae Rx1	67.188	99.225	0.667
comGF/cglF	Streptococcus pneumoniae D39	67.188	99.225	0.667
comGF/cglF	Streptococcus pneumoniae R6	67.188	99.225	0.667
comGF/cglF	Streptococcus pneumoniae TIGR4	67.188	99.225	0.667
comGF/cglF	Streptococcus mitis SK321	66.142	98.45	0.651
comYF	Streptococcus mutans UA140	44	96.899	0.426
comYF	Streptococcus mutans UA159	43.2	96.899	0.419
comGF	Lactococcus lactis subsp. cremoris KW2	39.37	98.45	0.388